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Reference of 312959-24-3, An article , which mentions 312959-24-3, molecular formula is C48H47FeP. The compound – 1,2,3,4,5-Pentaphenyl-1′-(di-tert-butylphosphino)ferrocene played an important role in people’s production and life.

In spite of the wide application potential of 1,2,4,5-tetrazines, particularly in live-cell and in vivo imaging, a major limitation has been the lack of practical synthetic methods. Here we report the in situ synthesis of (E)-3-substituted 6-alkenyl-1,2,4,5-tetrazine derivatives through an elimination-Heck cascade reaction. By using this strategy, we provide 24 examples of pi-conjugated tetrazine derivatives that can be conveniently prepared from tetrazine building blocks and related halides. These include tetrazine analogs of biological small molecules, highly conjugated buta-1,3-diene-substituted tetrazines, and a diverse array of fluorescent probes suitable for live-cell imaging. These highly conjugated probes show very strong fluorescence turn-on (up to 400-fold) when reacted with dienophiles such as cyclopropenes and trans-cyclooctenes, and we demonstrate their application for live-cell imaging. This work provides an efficient and practical synthetic methodology for tetrazine derivatives and will facilitate the application of conjugated tetrazines, particularly as fluorogenic probes for live-cell imaging. Stitching probes together: The in situ synthesis of (E)-3-substituted 6-alkenyl-1,2,4,5-tetrazine derivatives through an elimination-Heck cascade reaction is reported. 24 examples of pi-conjugated tetrazine derivatives are provided, including conjugated fluorescent probes that show drastic fluorescent turn-on when reacted with dienophiles. Their suitability for live-cell imaging is demonstrated. TCO=trans-cyclooctene.

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Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Reference of 312959-24-3, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 312959-24-3, C48H47FeP. A document type is Patent, introducing its new discovery.

The invention relates to the following formula (III) as shown in the diaryl sulfoxide compound synthesis method, the method comprises: in a nitrogen atmosphere and at room temperature, to point pen in an organic solvent (I) compounds, of formula (II) compound, catalyst, oxidizing agent and auxiliary agent, for 70 – 90 C stirring reaction 7 – 10 hours, after the reaction by adding saturated salt water diluted, extracted with ethyl acetate to 2 – 3 times, separated and the organic phase with anhydrous sodium sulfate drying, distillation under reduced pressure, the residue by silica gel column chromatography separation of the fast, to obtain the compound of formula (III), wherein R1 , R2 Are each independently selected from H, C1 – C6 Alkyl, C1 – C6 Alkoxy or halogen. The method through a specific reactant, and catalyst, oxidizing agent, additives and the organic solvent or the like optimizes the components of selection, the sulfoxide imine compound fast N – methylation reaction, and have achieved a high yield of the technical effects, demonstrate the broad market prospect. (by machine translation)

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Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.312959-24-3, Name is 1,2,3,4,5-Pentaphenyl-1′-(di-tert-butylphosphino)ferrocene, molecular formula is C48H47FeP. In a Article£¬once mentioned of 312959-24-3, Product Details of 312959-24-3

Synthesis, Structure, Theoretical Studies, and Ligand Exchange Reactions of Monomeric, T-Shaped Arylpalladium(II) Halide Complexes with an Additional, Weak Agostic Interaction

A series of monomeric arylpalladium(II) complexes LPd(Ph)X (L = 1-AdP tBu2, PtBu3, or Ph 5FcPtBu2 (Q-phos); X = Br, I, OTf) containing a single phosphine ligand have been prepared. Oxidative addition of aryl bromide or aryl iodide to bis-ligated palladium(0) complexes of bulky, trialkylphosphines or to Pd(dba)2 (dba = dibenzylidene acetone) in the presence of 1 equiv of phosphine produced the corresponding arylpalladium(II) complexes in good yields. In contrast, oxidative addition of phenyl chloride to the bis-ligated palladium(0) complexes did not produce arylpalladium(II) complexes. The oxidative addition of phenyl triflate to PdL2 (L = 1-AdPtBu2, PtBu 3, or Q-phos) also did not form arylpalladium(II) complexes. The reaction of silver triflate with (1-AdPtBu2)Pd(Ph)Br furnished the corresponding arylpalladium(II) triflate in good yield. The oxidative addition of phenyl bromide and iodide to Pd(Q-phos)2 was faster than oxidative addition to Pd(1-AdPtBu2)2 or Pd(PtBu3)2. Several of the arylpalladium complexes were characterized by X-ray diffraction. All of the arylpalladium(II) complexes are T-shaped monomers. The phenyl ligand, which has the largest trans influence, is located trans to the open coordination site. The complexes appear to be stabilized by a weak agostic interaction of the metal with a ligand C-H bond positioned at the fourth-coordination site of the palladium center. The strength of the Pd…H bond, as assessed by tools of density functional theory, depended upon the donating properties of the ancillary ligands on palladium.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 312959-24-3, you can also check out more blogs about312959-24-3

Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate