Tag: M.W:500-600

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

Under argon protection,Add in 50 mL Schlenk bottle(SO3Na) 3-R6, 4.73 mmol of [n_C16H33 (EO) 16N + H = C (N (CH3) 2) 2] [CH3SO3-] and 20 mL of acetonitrile,The reaction mixture was stirred at room temperature for 72 hours, filtered and the filtrate was removed under reduced pressure to give an orange yellow viscous liquid in 94% yield.

63995-70-0 Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate 6099338, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Qingdao University of Science and Technology; JIN, XIN; LI, SHU MEI; ZHAO, KUN; (11 pag.)CN103483381; (2016); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: NHC-Cu(I) complexes 1-3 were synthesized by the following route:a solution of imidazolium salt (0.4 mmol), copper powder (0.12 g,0.5 mmol) and POP (0.64 g, 1.2 mmol) reacted in CH3CN (5 mL) at 50Cfor 12 h. The resulting mixture was filtered through a plug of Celite andconcentrated to ca. 1 mL. Addition of Et2O (10 ml) to the filtrate affordeda pale yellow precipitate, which was collected and washed withEt2O. And the product was recrystallized with ethanol., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Wang, Jinglan; Chen, Hongyun; Xu, Shengxian; Su, Qingzhi; Zhao, Feng; He, Haifeng; Journal of Photochemistry and Photobiology A: Chemistry; vol. 387; (2020);,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1070663-78-3,Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine,as a common compound, the synthetic route is as follows.

1070663-78-3, [Pd(allyl)(brettphos)]OTf was synthesized according to the literature.[4] A dry Schlenk flask equipped with a Teflon-coated magnetic stirring bar was charged with [(allyl)PdCl]2 (183 mg, 0.5 mmol) followed by AgOTf (257 mg, 1.0 mmol). The flask was fitted with a rubber septum, evacuated, and backfilled with nitrogen. This evacuation/nitrogen backfill cycle was repeated two additional times. Solvent (10 mLof THF) was added, and the reaction mixture was stirred at room temperature for 30min while protected from light. A second dry Schlenk flask was equipped with a magnetic stirring bar, fitted with a Schlenk frit, and charged with BrettPhos (537 mg,1.0 mmol). The flask was fitted with a rubber septum, and it was evacuated andbackfilled with nitrogen. This evacuation/nitrogen backfill cycle was repeated twoadditional times. The solution from the first Schlenk flask was transferred through amillipore filter (to remove AgCl) into the second Schlenk flask containing the ligand,rinsing with 5 mL of additional solvent (THF). This mixture was stirred at roomtemperature for 2 h. Hexanes (450 mL) was then added to the mixture to fullyprecipitate the product. The solid materials were then collected by suction filtration,washed with additional hexanes, and dried in vacuo to give 734 mg (86%) of the titlecompound as a yellow solid.

1070663-78-3 Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine 25112535, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Liu, Wentong; Kuang, Yi; Wang, Zhifan; Zhu, Jin; Wang, Yuanhua; Beilstein Journal of Organic Chemistry; vol. 15; (2019); p. 542 – 550;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

General procedure: Cu(I) complexes were synthesized by the following route: [Cu(CH3CN)4](PF6) (0.124g, 0.4mmol) and bis(2-(diphenylphosphanyl)phenyl ether (POP) (0.216g, 0.4mmol) reacted in dichloromethane (15mL) at 25C for 2h. Then, the corresponding ligand (0.4mmol) was dissolved in the degassed dichloromethane solution and injected into the mixed solution for 2h. The resulting mixture was filtered through a plug of Celite and concentrated to ca. 1mL. Addition of Et2O (10mL) to the filtrate afforded a pale yellow precipitate, which was collected and washed with Et2O. And the product was recrystallized with ethanol., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Chai, Chaoyang; Xu, Shengxian; Wang, Jinglan; Zhao, Feng; Xia, Hongying; Wang, Yibo; Inorganica Chimica Acta; vol. 488; (2019); p. 34 – 40;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

The heteroleptic nickel, palladium and platinum complexes (1?10) were prepared according to the general procedure shown in Scheme 1. To a stirring 15 ml methanolic solution of the ligand K2(p-CH3C6H4SO2N=CS2)¡¤2H2O (0.18 g, 0.5 mmol), K2(p-ClC6H4SO2N=CS2)¡¤2H2O (0.19 g, 0.5 mmol), K2(p-BrC6H4SO2N=CS2)¡¤2H2O (0.21 g, 0.5 mmol) or K2C2H5OCO(CN)CCS2 (0.13 g, 0.5 mmol) a 10ml aqueous solution of NiCl2¡¤6H2O (0.12 g, 0.5 mmol), K2PdCl4 (0.163 g, 0.5 mmol) or K2PtCl4 (0.21 g, 0.5 mmol) was added and in each case the reaction mixture was stirred for half an hour to get a clear solution. To this 25 ml solution was added a 10 ml dichloromethane solution of 1,1?-bis(diphenylphosphino)ferrocene (0.28 g, 0.5 mmol) with vigorous stirring and then further stirred for 12 h in the case of Ni and 24 h for Pd and Pt complexes. The volume of the reaction mixtures were reduced to 15 ml on rotary evaporator and the solid products thus obtained were filtered off and washed with H2O?CH3OH (40:60 v/v) and dried in vacuo over calcium chloride., 12150-46-8

As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Article; Singh, Santosh K.; Chauhan, Ratna; Diwan, Kiran; Drew, Michael G.B.; Bahadur, Lal; Singh, Nanhai; Journal of Organometallic Chemistry; vol. 745-746; (2013); p. 190 – 200;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

1070663-78-3, Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1070663-78-3, General procedure: The general procedure is followed using 259 mg (0.50 mmol) of 33 [(cinnamyl)PdCl]2, 257 mg (1.00 mmol) of 22 AgOTf, 537 mg (1.00 mmol) of BrettPhos in anhydrous 2-MeTHF to give 884 mg (0.97 mmol, 97%) of the title compound as a yellow solid. 1H NMR (400 MHz, CDCl3, delta): complex spectrum-see FIG. 5. 13C NMR (100 MHz, CDCl3, delta): complex spectrum-see FIG. 6. 31P NMR (162 MHz, CDCl3, delta): 57.6, 39.5. 19F NMR (376 MHz, CDCl3, delta): -78.1 (s, 3F). Anal. Calcd. for C45H62F3O5PPdS: C, 59.43; H, 6.87. Found: C, 59.26; H, 6.68.

The synthetic route of 1070663-78-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Johnson Matthey Public Limited Company; Colacot, Thomas; Jon Deangelis, Andrew; (66 pag.)US9777030; (2017); B2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The reactions were run in a CEM Corp. MARS microwave fitted with a fiber optic temperature probe and a port on top for a reflux condenser.1 mmol of Mo(CO)6 and dppe (0.425 g, 1.1 mmol) were combined with 20 mL of 1-propanol in a two-neck 100 mL RB flask. To this mixture was added NaBH4 (0.128 g, 3.3 mmol). The flaskwas placed in themicrowave and a reflux condenser attached through a hole in the top of the microwave. The mixture was sparged with nitrogen. The mixture was heated under nitrogen at 400 W for 1.5 min to reach reflux temperature. Once the reflux temperature was reached the microwave power was reduced and the temperature maintained for 18 min. The mixture was cooled to room temperature and 2?4 mL of water was added to the reaction to dissolve excess NaBH4 and promote product precipitation. The reaction was cooled ?10 ¡ãC for several hours. The light yellow complex was filtered in air and washed with 2¡Á5 mL of petroleum ether/diethyl ether(1:1) mixture resulting in 580 mg of Mo(CO)4dppe after drying, a 95percent yield.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Birdwhistell, Kurt R.; Schulz, Brian E.; Dizon, Paula M.; Inorganic Chemistry Communications; vol. 26; (2012); p. 69 – 71;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

General procedure: NHC-Cu(I) complexes 1-3 were synthesized by the following route:a solution of imidazolium salt (0.4 mmol), copper powder (0.12 g,0.5 mmol) and POP (0.64 g, 1.2 mmol) reacted in CH3CN (5 mL) at 50Cfor 12 h. The resulting mixture was filtered through a plug of Celite andconcentrated to ca. 1 mL. Addition of Et2O (10 ml) to the filtrate affordeda pale yellow precipitate, which was collected and washed withEt2O. And the product was recrystallized with ethanol.2.2.6. [Cu(Ph-BenIm-methPy)](PF6) (1)The product was a white powder. Yield: 0.67 g, 67%. 1H NMR(400 MHz, DMSO-d6): delta 8.25 (d, J =8.3 Hz, 1 H), 8.20 – 8.05 (m, 2 H),7.48 (t, J =7.2 Hz, 1 H), 7.34 (t, J =7.7 Hz, 9 H), 7.22 (dd, J=18.7,7.0 Hz, 9 H), 7.06 (dt, J=26.2, 7.6 Hz, 11 H), 6.92 (s, 4 H), 6.78 (s,2 H), 6.72 (d, J =7.4 Hz, 2 H), 5.36 (s, 2 H), 1.90 (d, J =23.9 Hz, 3 H).13C NMR (101 MHz, DMSO-d6). delta 158.85, 157.42, 157.37, 157.31,149.91, 140.91, 134.83, 134.73, 133.63, 132.93, 132.29, 131.54,131.38, 131.23, 130.14, 128.76, 128.59, 127.55, 125.85, 125.08,124.68, 124.54, 123.73, 123.59, 123.46, 122.98, 119.86, 113.33,112.59, 111.80, 51.57, 24.16. 31P NMR (162 MHz, DMSO) delta -10.31 (s),-143.84 (quint). HRMS (m/z, ESI+): calcd. For C56H45CuN3OP2 ([M]+)900.2334; found 900.2358. Anal. Calcd. For C56H45CuF6N3OP3(1045.4): C 64.28, H 4.33, N 4.02; found: C 64.51, H 4.22, N 4.09., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Wang, Jinglan; Chen, Hongyun; Xu, Shengxian; Su, Qingzhi; Zhao, Feng; He, Haifeng; Journal of Photochemistry and Photobiology A: Chemistry; vol. 387; (2020);,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

1070663-78-3, Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1070663-78-3, EXAMPLE FORTY-FIVE: Synthesis of BrettPhosPd(3,5-dimethylphenyl)Br (19); In a nitrogen filled glovebox, a solution of BrettPhos (1, 172 mg, 321 mumol), 3,5- dimethylbromobenzene (225 muL) and THF (15 rnL) was added to solid (COD)Pd(CH2SiPhMe2)2 (150 mg, 292 mumol) in an oven-dried 100 mL round bottom flask. The flask was capped, and the resulting yellow solution was allowed to stand for 48 h at rt. After this time, pentane (60 mL) was layered on top of the THF solution and the vial was allowed to stand for 24 h resulting in the formation of crystals. After 24 h, the crystals were collected via vacuum filtration in the glovebox, and dried under vacuum to provide 19 (185 mg, 77%) as light-yellow microcrystalline powder as a THF mono-solvate: 1H NMR (400 MHz, CD2Cl2, mixture of rotomers) delta 7.01-7.08 (m, 2H – major, 4H – minor), 6.90 (s, 2H – minor), 6.89 (dd, J= 9.2, 2.8, IH – major), 6.83 (d, J= 8.8 Hz, IH -major), 6.64 (s, 2H – major), 6.41 (s, IH – minor, 2H – major), 4.31 (s, 3H – minor), 3.78 (s, 3H -major), 3.59 (s, 3H – minor), 3.32 (s, 3H – major), 3.03-3.06 (m, IH – major), 2.88-2.92 (m, IH – major), 2.70-2.79 (m, 2H – major), 2.45-2.51 (m, 2H – major), 2.32-2.37 (m, 2H -minor), 2.14 (s, 6H -major), 2.12 (s, 6H – minor), 1.50-1.90 (m, major and minor), 1.05-1.45 (m), 0.75- 0.90 (m, 12H – major and minor), 0.55-0.65 (m, 2H – minor); 31P NMR (162 MHz, CD2Cl2, mixture of rotomers) delta 45.0 (minor), 37.5 (major). Anal CaIc C43H62BrO2PPd: C, 62.36; H, 7.55. Found: C, 62.52; H, 7.68.

The synthetic route of 1070663-78-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; MASSACHUSETTS INSTITUTE OF TECHNOLOGY; WO2009/76622; (2009); A2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: [Cu(CH3CN)4]ClO4 (32.6 mg, 0.100 mmol) was added to a DCMsolution (about 12 mL) of dap (10.7 mg, 98percent, 0.0500 mmol) andxantphos (59.0 mg, 98percent, 0.100 mmol) under a stream of dry argonby using Schlenk techniques at room temperature and a vacuumlinesystem, then orange-red solution was obtained quickly andstirred for 1 h at room temperature. The above process can alsobe carried out in air with the existence of oxygen. After filtrationthrough absorbent cotton, layering n-hexane onto the DCM solutionin air produced the product as bluish violet to black-blue blockcrystals in 76percent yield (63.0 mg)., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Yao, Xi-Xi; Guo, Ya-Meng; Liu, Rong; Feng, Xiao-Yan; Li, Hao-Huai; Liu, Nian; Yang, Feng-Lei; Li, Xiu-Ling; Polyhedron; vol. 92; (2015); p. 84 – 92;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate