Tag: M.W:500-600

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of Tetrakis(acetonitrile)copper(I) tetrafluoroborate ([Cu(NCCH3)4]BF4, 3.11 g, 33.0 mmol) and Bis[(2-diphenylphosphino)phenyl]ether (O[C6H4P(C6H5)2]2, DPEphos, 5.33 g, 33.0 mmol) in 300 ml of CH2Cl2 was stirred at room temperature for 3 h. Upon addition of 1,10-Phenanthroline (C12H8N2, phen, 1.78 g, 33.0 mmol) the clear solution turned bright yellow, remained clear, and was stirred for an additional 2 h. Approximately 900 ml of diethyl ether ((CH3CH2)2O) was added to the solution to precipitate a bright yellow solid. The solution containing the newly precipitated solid was then left in the refrigerator for one day. It was vacuum filtered using a medium frit, washed with diethyl ether and dried under vacuum. A bright yellow powder was isolated (yield: 8.00 g, 93 percent)., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Kubi?ek, Katharina; Thekku Veedu, Sreevidya; Storozhuk, Darina; Kia, Reza; Techert, Simone; Polyhedron; vol. 124; (2017); p. 166 – 176;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: PyIm-Cu(I) complexes P1?P4 were synthesized by the following route: [Cu(CH3CN)4](PF6) (0.124g, 0.4mmol) and POP (0.216g, 0.4mmol) reacted in dichloromethane (15ml) at 25¡ãC for 2h. Then, the corresponding PyIm ligand (0.4mmol) was dissolved in the degassed dichloromethane solution and injected into the mixed solution for 2h. The resulting mixture was filtered through a plug of Celite and concentrated to ca. 1ml. Addition of Et2O (10ml) to the filtrate afforded a pale yellow precipitate, which was collected and washed with Et2O. And the product was recrystallized with ethanol., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Wang, Jinglan; Chai, Chaoyang; Xu, Shengxian; Zhao, Feng; Xia, Hongying; Wang, Yibo; Inorganica Chimica Acta; vol. 484; (2019); p. 237 – 244;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a nitrogen filled glove box, [(1tBuIndenyl)Pd(,1Cl)]2 (100 mg, 0.16 mmol) and 1,1?-bis(diphenylphosphino)ferrocene (DPPF) (177 mg, 0.32 mmol) were added to a 100 mL Schlenk flask. Methanol (20 mL) was added and the mixture was stirred at roomtemperature for 2 hours. During this time, the mixture became homogenous with a deep red color. The flask was opened to air and the solvent was removed with a rotary evaporator to yield a red oil. Pentane was added, followed by sonication; vacuum filtration produced a red crystalline solid (225 mg, 81percent).

12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Patent; YALE UNIVERSITY; HAZARI, Nilay; MELVIN, Patrick; HRUSZKEWYCZ, Damian; (92 pag.)WO2016/57600; (2016); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

A solution of the ligand DPEphos (0.355g, 0.66 mmol) in30 mL of dichloromethane was added drop by drop to a solution of CoCl2.6H2O (0.166g, 0.70 mmol) in 50 mL dichloromethane. The reaction mixture was refluxed under nitrogen for 1 h. After cooling the reaction mixture, the solvent was evaporated and the resultant solid mass was washed several times with ether and hexane. Finally, after drying under vacuum,a blue compound was obtained which was re-crystallized from dichloromethane. Yield: 90percent. Anal. Calcd. forC36H28Cl2OP2Co (percent): C, 64.69; H, 4.22, Co, 8.82; Found: C,64.12; H, 4.19; Co, 8.78; Selected peak assignments in MSESIm/z (percent): 1360 (5), [2M+Na]+; 1301 (30), [2M-Cl]+; 746(20), [M+2K]2+; 690 (30) [M+Na]+; 539 (50), [DPEphos]+;Selected IR frequencies (cm-1, KBr): 3051, 2985 (C-H);1485, 1435 (C=C); 1101 (C-O-C); 506 (Co-P); 336, 322 (Co-Cl) ); UV-Vis (CH2Cl2), max (nm): 246, 647, 713., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Sahu, Debojeet; Banik, Biplab; Borah, Malabika; Das, Pankaj; Letters in Organic Chemistry; vol. 11; 9; (2014); p. 671 – 676;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1070663-78-3,Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine,as a common compound, the synthetic route is as follows.

1070663-78-3, EXAMPLE FORTY-FOUR: Synthesis of BrettPhosPdPhCl (18); In a nitrogen filled glovebox, a solution of BrettPhos (1, 51.0 mg, 96 mumol), chlorobenzene (100 muL) and THF (4 mL) was added to solid (COD)Pd(CH2SiPhMe2^ (40.8 mg, 80 mumol) in an oven-dried 20 mL vial. The vial was capped, and the resulting yellow solution was allowed to stand for 48 h at rt. After this time, pentane (14 mL) was layered on top of the THF solution and the vial was allowed to stand for 24 h resulting in the formation of crystals. After 24 h, the crystals were collected via vacuum filtration in the glovebox, and dried under vacuum to provide 18 (42 mg, 69%) as light-yellow microcrystalline powder: 1H NMR (400 MHz, CD2Cl2, mixture of rotomers) delta 7.28-7.30 (m, 2H – minor), 7.07-7.10 (m, 2H – minor), 7.04 (s, 2H – major), 7.02 (s, 2H – minor), 6.82-6.92 (m, major and minor), 6.76-6.82 (m, IH – minor, IH – major), 4.29 (s, 3H – minor), 3.79 (s, 3H -major), 3.59 (s, 3H – minor), 3.34 (s, 3H – major), 2.96-3.03 (m, IH – major), 2.88-2.95 (m, IH – major), 2.71-2.80 (m, 2H – major), 2.46-2.53 (m, 2H – major), 2.32-2.37 (m, 2H -minor), 1.50-1.90 (m, major and minor), 1.08-1.45 (m), 0.78-0.92 (m, major and minor), 0.55-0.65 (m, 2H – minor); 31P NMR (162 MHz, CD2Cl2, mixture of rotomers) delta 46.8 (minor), 38.6 (major). Anal CaIc for C4iH58C102PPd: C, 65.16; H, 7.74;. Found: C, 65.42; H, 7.53.

As the paragraph descriping shows that 1070663-78-3 is playing an increasingly important role.

Reference£º
Patent; MASSACHUSETTS INSTITUTE OF TECHNOLOGY; WO2009/76622; (2009); A2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

The solutions of (0.0256 g, 0.1 mmol) of H2dzin 10 cm3 of methanol, (0.1 mmol, 0.0233 g) ofMnCl2.6H2O in 10 cm3 of methanol) and (0.0554 g,0.1mmol of 1,1′-bis(diphenyl phosphine) ferrocene(dppf) were mixed and refluxed at 55 oC for 2 h to give brown colored precipitate and the solutionswas filtered and finally it was dried in an open air.Yield=81percent, d.p= 238¡ãC. Anal. Calc. percent for C47 H41 ClN4 P2Mn S Fe:C, 62.58; H, 4.58; N, 6.21, S, 3.55, Mn,6.09, Cl, 3,93 .Found percent: C, 62.87, H, 4.82; N, 6.53, S;3.88, Mn; 6.27, Cl.4.11.

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Mohamad, Hikmat Ali; Oriental Journal of Chemistry; vol. 34; 4; (2018); p. 1919 – 1925;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Under argon protection, bis(2-diphenylphosphinophenyl)ether (Compound 2) 538 g, toluene solvent was added to the reaction vessel.700 mL, 8.8 mL of trifluoromethanesulfonic acid, 150 mL of acetone, the reaction system was heated to 200 C, and after 16 h of reaction, it was reduced toAt room temperature, after extraction, drying and recrystallization, the desired product 4,5-bisdiphenylphosphino-9,9-dimethyloxaxan (Compound 1) is obtained.549 g (yield 95%)., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Henan Academy Of Sciences Chemical Institute Co., Ltd.; Liu Tingting; Chen Hui; Zhou Duo; Zhao Shunwei; Li Yunfei; Yang Zhenqiang; Cui Fumin; Duan Zheng; Yang Ruina; (4 pag.)CN109942631; (2019); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.146960-90-9,1,1′-Bis(dicyclohexylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

Example 21 Preparation of[DCyPFc RuCI2AMPY] Into a 200 mL stirred glass reactor are introduced 3.2 g of RuCI2(PPh3)3and 2.32 g of DCyPFc as solids followed by 100 mL of nitrogen saturated MEK. Stirring is started immediately and the slurry is stirred for 28 hours.3P{ H} NMR analysis of a NMR sample obtained by diluting a sample from the reaction mixture with C6D6shows that all DCyPFc has reacted and that the only free phosphine is PPh3released from RuCI2(PPh3)3.To the intermediate slurried in MEK is added 0.42 g of AMPY after dilution in 10 ml of MEK over the period of 10 minutes. The reaction mixture is stirred for 60 hours. The obtained thick slurry of a tan brown product is suction filtered using a Buechner funnel and filter paper until a wet cake of product is obtained. Washing with MEK is continued until the MEK filtrate is uncoloured. The yellow product is dried at 10 mbar, 30C for 48 hours. A sample was slurried in IPA and again filtered.The identity of the solid is confirmed by a combination of H and3P{ H} NMR analysis. By3P{ H} NMR analysis 2 isomers with delta = 51 ppm (major broad resonance) and delta = 48 ppm (minor broad resonance) are visible. The AMPY resonances for the major complex are delta = 9.94 (d), 7.73 (t), 7.40 (t), 7.35 (t) (all integration as 0.75 H) 5.07 (s, 1 .5 H), the AMPY resonances for the minor complex are delta = 9.80 (d), 8.06 (t), 7.93 (t), 7.64 (t) (all integration as 0.25 H), 5.01 (s, 0.5 H). The 2 x 4 CH resonances of ferrocene are at delta = 4.23 (m), 4.08 (m). The remaining resonances of the cyclohexyl – resonances (44) are a broad series of multiplets at delta = 2.2 – 0.94 ppm., 146960-90-9

The synthetic route of 146960-90-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; JOHNSON MATTHEY PUBLIC LIMITED COMPANY; FACCHETTI, Sarah; NEDDEN, Hans; WO2015/79207; (2015); A2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

General procedure: A solution of [Cu(CH3CN)4](ClO4) (35.3mg, 0.108mmol) and 1,2-bis(diphenylphosphino)ethane (dppe) (43.2mg, 0.108mmol) in CH2Cl2 (10mL) was stirred for 30min at room temperature. A solution of Hbmp (22.6mg, 0.108mmol) in CH2Cl2 (5mL) was added, and this mixture was stirred for another 2h to give a light-yellow solution. The solvent was evaporated to dryness at reduced pressure. The residue was dissolved in a mixture of acetone/dichloromethane (1:5 v/v), and slow diffusion of petroleum ether into the above solution gave light-yellow crystals of 2 (69.4mg, 0.090mmol, 83percent)., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Di, Bao-Sheng; Chen, Jing-Lin; Luo, Yan-Sheng; Zeng, Xue-Hua; Qiu, Lu; He, Li-Hua; Liu, Sui-Jun; Wen, He-Rui; Polyhedron; vol. 119; (2016); p. 525 – 531;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Complex 1 (0.112 g, 0.20 mmol) was dissolved in dryMeCN (20 ml) under argon, and Me3NO2H2O (0.022 g,0.20 mmol) was added. The color of the solution changed from red to brown immediately. After stirring at room temperature for 0.5 h, the resulting solution was mixedwith dppf (0.056 g, 0.10 mmol) and stirred for 3 h at the room temperature. The solvent was removed on a rotary evaporator, and the residue was subjected to preparativeTLC separation using CH2Cl2/petroleum ether (v/v = 1:1)as the eluent. From the main red band, complex 3 wasobtained as a red solid (0.072 g, 81 percent). IR (KBr disk cm-1): mC:O 2036 (vs), 1973 (vs), 1922 (m). 1H NMR(400 MHz, CDCl3, ppm): 1.67 (s, 6 H, 2 CH, 4 SCHaHe),2.22 (s, 4 H, 4 SCHaHe), 4.22 (s, 4 H, C5H4), 4.46 (s, 4 H,C5H4), 6.35 (s, 4 H, C6H5), 7.12 (s, 6 H, C6H5), 7.35 (m, 12H, C6H5), 7.59 (s, 8 H, C6H5). 31P NMR (161.9 MHz,CDCl3, 85 percent H3PO4, ppm): 55.1 (s). Anal. Calc. for C68-H62Fe5O10P2Se4: C, 48.2; H, 3.7. Found: C, 48.4; H, 3.4 percent.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Li, Chang-Gong; Cui, Mao-Jin; Xue, Feng; Zhu, Yong; Li, Yong-Fang; Shang, Jing-Yan; Niu, Hong-Ying; Transition Metal Chemistry; vol. 40; 5; (2015); p. 493 – 500;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate