Tag: M.W:500-600

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

General procedure: A mixture of 0.0630 g [Cu(CH3CN)4]BF4 (0.2 mmol), 0.0464 gdpq (0.2 mmol) and 0.1157 g xantphos (0.2 mmol) were dissolved in the mixed solvents of 5 mL CH3OH and 5 mL CH2Cl2, stirred atroom temperature for 6 h. The filtrate was evaporated slowly at room temperature for around 4 days to yield yellow crystalline products. Yield: 80%. Anal. Calc. for C55H49BCuF4N4O3.50P2: C,63.87; H, 4.78; N, 5.42. Found: C, 65.11; H, 4.16; N, 5.76%., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Kuang, Xiao-Nan; Lin, Sen; Liu, Jian-Ming; Han, Hong-Liang; Liu, Min; Xin, Xiu-Lan; Yang, Yu-Ping; Li, Zhong-Feng; Jin, Qiong-Hua; Li, Si-Fan; Li, Yue-Xue; Feng, Yue-Bing; Polyhedron; vol. 165; (2019); p. 51 – 62;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Dpa (0.0368 g, 0.2 mmol) and POP (0.0539 g, 0.1 mmol) wereadded into the stirring solution of AgClO4 (0.0208 g, 0.1 mmol),in a mixture of CH3CN (5 ml) and H2O (5 ml) at ambient temperature.The mixture was stirred for 6 h. The insoluble residues wereremoved by filtration, and the brown filtrate was evaporatedslowly at room temperature for about four days to yield whitecrystals. Yields: 42percent., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Zhang, Yan-Ru; Cui, Yang-Zhe; Jin, Qiong-Hua; Yang, Yu-Ping; Liu, Min; Li, Zhong-Feng; Bi, Kai-Lun; Zhang, Cun-Lin; Polyhedron; vol. 122; (2017); p. 86 – 98;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1070663-78-3,Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine,as a common compound, the synthetic route is as follows.

1070663-78-3, [(i3-indenyl)Pd(.i-OTf)j2 (0.10 g, 0.135 mmol) and BrettPhos (0.145 g, 0.270 mmol) were added to a 20 mL vial equipped with a flea stir bar. THF (10 mL) was added to the vialand a red homogenous mixture was observed. The mixture was stirred for one hour at room temperature, at which time the solvent was removed under reduced pressure. The red oil was titrated with pentane to yield a dark red solid. Yield: 0.220 g, 90%. 1H NMR (CDCl3, 500 MHz): 7.44 (s, 1H), 7.16-6.93 (m, 7H), 6.82 (d, J = 6.5 Hz, 1H), 6.63 (s, 1H), 6.06 (s, 1H), 4.17 (d, 5.4 Hz, 1H), 3.92 (s, 3H), 3.33 (s, 3H), 3.15 (sept, J = 5.6 Hz, 1H), 2.79 (q, J = 5.7Hz, 1H), 2.56 (q, J = 5.7 Hz, 1H), 2.27-1.67 (m, 16H), 1.54-0.81 (m, 20H), 0.69 (d, J = 6.1Hz, 3H), 0.45 (d, J = 6.2 Hz, 3H) ppm. 13C{1H} NMR (126 MHz, CDCl3): 154.85, 154.17,153.51, 151.21, 151.08, 150.96, 139.93, 139.89, 135.74, 135.33, 134.74, 134.58, 129.16,127.13, 125.74, 125.47, 124.60, 122.89, 122.59, 120.93, 119.38, 116.60, 116.43, 115.46,114.21, 114.16, 112.88, 112.84, 109.62, 109.58, 70.76, 67.95, 56.04, 54.71, 39.16, 38.98,38.71, 38.51, 34.38, 34.19, 32.77, 32.21, 31.94, 30.53, 30.51, 30.30, 29.79, 29.24, 27.35,27.25, 27.09, 26.99, 26.87, 26.79, 26.75, 26.67, 26.42, 25.83, 24.93, 24.61, 24.31, 24.16,23.85 ppm. 31P{1H} NMR (CDCl3 100 MHz): 58.19 ppm. 19F NMR (471 MHz, CDCl3):-78.01 ppm.

As the paragraph descriping shows that 1070663-78-3 is playing an increasingly important role.

Reference£º
Patent; YALE UNIVERSITY; HAZARI, Nilay; MELVIN, Patrick; (59 pag.)WO2018/183328; (2018); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Synthesis of the phosphine oxidesThe phosphine oxides were synthesized by oxidation ofthe corresponding phosphines. Calculated amounts of H2O2(30percent) were added slowly to the vigorously stirred THF solutionof the respective phosphine. Stirring was maintainedat room temperature for 2 h. After evaporation of THF, theresidue was treated with acetone-ethyl acetate to obtain therespective phosphine oxide product as a precipitate. The precipitatesthus obtained were filtered off and dried in a vacuum.All melting points were above 360 C with decomposition. DPEPO: 1H NMR (250 MHz, CDCl3): d = 7:75 ? 7:64(m, 9H, Phen-H), 7.42 (m, 13H, Phen-H), 7.05 ? 7.04 (t, 2H,Phen-H), 7.07 (t, 2H, Phen-H), 7.08 (t, 2H, Phen-H). ? MS(EI): m=z = 570. Yield 84percent., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Pietraszkiewicz, Marek; Mal, Suraj; Pietraszkiewicz, Oksana; Gorski, Krzysztof; Chelwani, Nitin; Zeitschrift fur Naturforschung, B: Chemical Sciences; vol. 69; 2; (2014); p. 239 – 247;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A benzene solution (20mL) of 1 (100mg, 0.148mmol) and dppf (82mg, 0.148mmol) was refluxed for 45min. The solvent was removed under reduced pressure and the residue was chromatographed by TLC on silica gel. Elution with n-hexane/CH2Cl2 (3:1 v/v) developed two bands. The faster moving band gave a very dark solid, tentatively assigned as [Fe3(CO)9(mu3-Te)2(kappa1-dppfO)] (15mg, 9percent), and the second band afforded [Fe3(CO)8 (mu3-Te)2 (kappa2-dppf)] (6) (60mg, 35percent) as red crystals after recrystallization from hexane/CH2Cl2 at 4¡ãC. Characterization data for [Fe3(CO)8(mu3-Te)2(kappa1-dppfO)]: IR (nu(CO), CH2Cl2): 2053s, 2039vs, 2010vs, 1996 vs, 1964s cm?1. 1H NMR (CDCl3): delta 8.23?7.43 (m, 20H), 4.4?4.38 (m, 4H), 3.35?3.31 (m, 4H). 31P{1H} NMR (CDCl3): delta 51.0 (s), 28.0 (s). Characterization data for 6: IR (nu(CO), CH2Cl2): 2039s, 1998vs, 1963s, 1951mcm?1. 1H NMR (CDCl3): delta 7.60?7.43 (m, 8H), 7.4?7.43 (m, 12H), 4.47 (s, 4H), 4.38 (s, 4H). 31P{1H} NMR (CDCl3): delta 51.2 (s). ESI-MS: m/z 1145.47 (M+, calc. 1145.35).

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Rahaman, Ahibur; Lisensky, George C.; Tocher, Derek A.; Richmond, Michael G.; Hogarth, Graeme; Nordlander, Ebbe; Journal of Organometallic Chemistry; vol. 867; (2018); p. 381 – 390;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a Schlenk flask containing Cu(CH3CN)4*BF4 (0.032g,0.1 mmol) and DPEphos (0.054g, 0.1 mmol) was added CH2Cl2 (10 mL) under nitrogen atmosphere, and the solution (i) was stirred at room temperature (RT) for 4 h. A CH2Cl2 (10 mL) and CH3OH (10 mL) mixture solution of NHPIP (0.034 g, 0.1 mmol) and KOH (0.006 g, 0.1 mmol) was also stirred at room temperature (RT) for 4 h to give solution (ii). Then, (ii) was added into (i) by a syringe under nitrogen. After reaction of 48 h at RT, the solution was filtered and the solventwas removed by a rotary evaporator. The residue was dissolved in diethyl ether, and orange block crystals were obtained by the solvent evaporation method (0.080 g, 85percent). IR (nu, cm?1, Figure S1 (Supporting Information)): 3374 m, 2929 s, 2851 m, 1740 w, 1701 w, 1651 w, 1590 s, 1542 w, 1511 m, 1461 m, 1436 s, 1384 m, 1331 s, 1260 w, 1216 w, 1102 m, 1170 w, 1029 w, 859 w, 805 w, 734 m, 696 m. 1H NMR (400 MHz, [D6]DMSO, Figure S2): delta 8.94 (d, J = 8.1Hz, 2H), 8.58 (d, J = 8.5 Hz, 4H), 8.28 (d, J = 8.5 Hz, 2H), 7.66 (dd, J = 7.8, 4.7 Hz, 2H), 7.44 (t, J = 7.8 Hz, 2H), 7.31?7.22 (m, 6H), 7.18 (t, J = 7.4 Hz, 8H), 7.08 (t, J = 7.5Hz, 2H), 6.97 (d, J = 5.4 Hz, 8H), 6.62 (s, 2H). Anal. Calcd. for C55H38CuN5O3P2: C, 70.10; H, 4.06; N, 7.43percent. Found: C,71.2; H, 4.35; N, 7.62percent., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Liu, Xin Fang; Zhang, Xiao Yu; Li, Rong Fang; Feng, Xun; Bulletin of the Korean Chemical Society; vol. 37; 3; (2016); p. 282 – 286;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

The heteroleptic nickel, palladium and platinum complexes (1?10) were prepared according to the general procedure shown in Scheme 1. To a stirring 15 ml methanolic solution of the ligand K2(p-CH3C6H4SO2N=CS2)¡¤2H2O (0.18 g, 0.5 mmol), K2(p-ClC6H4SO2N=CS2)¡¤2H2O (0.19 g, 0.5 mmol), K2(p-BrC6H4SO2N=CS2)¡¤2H2O (0.21 g, 0.5 mmol) or K2C2H5OCO(CN)CCS2 (0.13 g, 0.5 mmol) a 10ml aqueous solution of NiCl2¡¤6H2O (0.12 g, 0.5 mmol), K2PdCl4 (0.163 g, 0.5 mmol) or K2PtCl4 (0.21 g, 0.5 mmol) was added and in each case the reaction mixture was stirred for half an hour to get a clear solution. To this 25 ml solution was added a 10 ml dichloromethane solution of 1,1?-bis(diphenylphosphino)ferrocene (0.28 g, 0.5 mmol) with vigorous stirring and then further stirred for 12 h in the case of Ni and 24 h for Pd and Pt complexes. The volume of the reaction mixtures were reduced to 15 ml on rotary evaporator and the solid products thus obtained were filtered off and washed with H2O?CH3OH (40:60 v/v) and dried in vacuo over calcium chloride.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Singh, Santosh K.; Chauhan, Ratna; Diwan, Kiran; Drew, Michael G.B.; Bahadur, Lal; Singh, Nanhai; Journal of Organometallic Chemistry; vol. 745-746; (2013); p. 190 – 200;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

2.679 g (8.635 mmol) of Rh(COD)(acac) was mixed with 20 ml of MEK in a 0.1 litre Schlenk flask. To the resulting slurry was added by syringe 1.22 ml of neat 54percent wt tetrafluoroboric acid in diethylether (8.74 mmol) by syringe over a period of 2 minutes, resulting in a red solution. After 5 minutes, 1.17 ml (9.66 mmol) of 1,5-cyclooctadiene was added by syringe. The brown red slurry was stirred for 20 minutes. Then 4.65 g (8.635 mmol) of DPEPhos was added in 2 portions over a period of 3 minutes. A orange slurry resulted after 5 minutes. The stirred slurry was reduced by evaporating MEK solvent until a slurry of the cationic complex in about 10 ml of residual solvent was obtained. To this slurry was added 20 ml of ethanol. The resulting orange slurry was degassed and stirred at room temperature for 1 hour before being filtered and washed with 2×5 ml of cold ethanol. After drying overnight (1 mbar, 2O0C), gave 7.26 g of complex [Rh cod DPEPhos] BF4 with approximately 0.75 equivalents of ethanol , Yield = 98.5 percent (8.51 mmol)., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; JOHNSON MATTHEY PUBLIC LIMITED COMPANY; NEDDEN, Hans Guenter; WO2010/1173; (2010); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

General procedure: Fe2(CO)6(mu-edt) (1) (100 mg, 0.268 mmol), Me3NO(21 mg, 0.280 mmol) and dppm (104 mg, 0.271 mmol) were heated in boiling acetonitrile (15 mL) for 30 min. After cooling to room temperature, the volatiles were removed under reduced pressure and the residue chromatographed by TLC on silica gel. Elution with hexane/CH2Cl2 (7:3, v/v) developed two bands. The faster-moving band afforded Fe2(CO)5(kappa1-dppm)(mu-edt) (3) (135 mg,69 percent) as red crystals, while the slower-moving band gave Fe2(CO)4(mu-dppm)(mu-edt) (4) [23] (17 mg, 9 percent) as red crystals after recrystallization from hexane/CH2Cl2 at 4 C., 12150-46-8

12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Rana, Shahed; Ghosh, Shishir; Hossain, Md. Kamal; Rahaman, Ahibur; Hogarth, Graeme; Kabir, Shariff E.; Transition Metal Chemistry; vol. 41; 8; (2016); p. 933 – 942;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

To a dichloromethane solution (20cm3) of [PtCl2(PhCN)2] (100 mg, 0.21 mmol), a solution of dppf (118 mg, 0.21 mmol) in dichloromethane was added. The resulting mixture was kept on stirring for 4 hours at room temperature. Solvent was evaporated under reduced pressure and residue was washed thoroughly with hexane followed by diethyl ether to remove excess phosphine. The residue was extracted with dichloromethane, filtered and passed through a Florisil Column. The ensuing solution at room temperature resulted yellow crystals (yield 152 mg, 87percent). Anal. Calcd. for C34H28P2FePtCl2: C, 49.78; H, 3.44percent. Found: C, 49.76; H, 3.46percent. 1H NMR (CDCl3) delta: 4.19 (br, 4H, C5H4), 4.37 (br, 4H, C5H4), 7.37?7.47 (m, Ph), 7.86 (br, Ph), 7.67-7.61 (m, Ph); 31P{1H}NMR (CDCl3) delta?:13.1 [1J(Pt-P) = 3776 Hz] ppm.

12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Article; Chauhan, Rohit Singh; Cordes, David B.; Slawin, Alexandra M.Z.; Yadav, Seema; Dash, Chandrakanta; Inorganica Chimica Acta; vol. 478; (2018); p. 125 – 129;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate