Tag: M.W:500-600

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The heteroleptic nickel, palladium and platinum complexes (1?10) were prepared according to the general procedure shown in Scheme 1. To a stirring 15 ml methanolic solution of the ligand K2(p-CH3C6H4SO2N=CS2)¡¤2H2O (0.18 g, 0.5 mmol), K2(p-ClC6H4SO2N=CS2)¡¤2H2O (0.19 g, 0.5 mmol), K2(p-BrC6H4SO2N=CS2)¡¤2H2O (0.21 g, 0.5 mmol) or K2C2H5OCO(CN)CCS2 (0.13 g, 0.5 mmol) a 10ml aqueous solution of NiCl2¡¤6H2O (0.12 g, 0.5 mmol), K2PdCl4 (0.163 g, 0.5 mmol) or K2PtCl4 (0.21 g, 0.5 mmol) was added and in each case the reaction mixture was stirred for half an hour to get a clear solution. To this 25 ml solution was added a 10 ml dichloromethane solution of 1,1?-bis(diphenylphosphino)ferrocene (0.28 g, 0.5 mmol) with vigorous stirring and then further stirred for 12 h in the case of Ni and 24 h for Pd and Pt complexes. The volume of the reaction mixtures were reduced to 15 ml on rotary evaporator and the solid products thus obtained were filtered off and washed with H2O?CH3OH (40:60 v/v) and dried in vacuo over calcium chloride.

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Singh, Santosh K.; Chauhan, Ratna; Diwan, Kiran; Drew, Michael G.B.; Bahadur, Lal; Singh, Nanhai; Journal of Organometallic Chemistry; vol. 745-746; (2013); p. 190 – 200;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

1.1 Preparation of N,N’-Di-(o-tolyl)-1,4-phenylenediamine To a 5 L round-bottomed 3-neck flask, equipped with reflux condenser, nitrogen inlet and exhaust, mechanical stirrer (equipped with PTFE stirrer rod, guide and stirrer blade) and a powder addition funnel, was added the 1,4-phenylenediamine (77.85 g, 0.720 mol, 1.0 eq.) and 2-bromotoluene (270.87 g, 1.584 mol, 2.2 eq.) and toluene (1500 mL). The resulting mixture was stirred for 10 mins, then degassed by sparging with nitrogen gas for 1 hour. The palladium(II) acetate (3.60 g, 0.1 eq.) and 1,1′-diphenylphosphinoferrocene (dppf) (8.88 g, 0.1 eq.) were then added and the mixture stirred under nitrogen for 15 mins. Sodium tert-butoxide (207.36 g, 2.16 mol, 3.0 eq.) was then charged as a solid. The mixture was heated to reflux and maintained at this temperature for 16 hours. GCMS after this time indicated complete reaction. The mixture was allowed to cool to room temperature and poured into a mixture of ice-water (1000 mL) and diethyl ether (500 mL). The phases were separated and the organic phase passed through celite (200 g). The filtrates were concentrated to dryness in vacuo and the crude product triturated from methanol. The product was recovered by filtration and the cake washed with methanol (2*250 mL). The solid product was then dried for 24 hours at 40¡ã C. in vacuo. The product was afforded as a pale white solid, 132.17 g, 65percent. NMR and GCMS data are consistent with the required structure., 12150-46-8

As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Patent; Merck Patent GmbH; US2008/217605; (2008); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The reactions were run in a CEM Corp. MARS microwave fitted with a fiber optic temperature probe and a port on top for a reflux condenser.1 mmol of Mo(CO)6 and dppe (0.425 g, 1.1 mmol) were combined with 20 mL of 1-propanol in a two-neck 100 mL RB flask. To this mixture was added NaBH4 (0.128 g, 3.3 mmol). The flaskwas placed in themicrowave and a reflux condenser attached through a hole in the top of the microwave. The mixture was sparged with nitrogen. The mixture was heated under nitrogen at 400 W for 1.5 min to reach reflux temperature. Once the reflux temperature was reached the microwave power was reduced and the temperature maintained for 18 min. The mixture was cooled to room temperature and 2?4 mL of water was added to the reaction to dissolve excess NaBH4 and promote product precipitation. The reaction was cooled ?10 ¡ãC for several hours. The light yellow complex was filtered in air and washed with 2¡Á5 mL of petroleum ether/diethyl ether(1:1) mixture resulting in 580 mg of Mo(CO)4dppe after drying, a 95percent yield.

12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Article; Birdwhistell, Kurt R.; Schulz, Brian E.; Dizon, Paula M.; Inorganic Chemistry Communications; vol. 26; (2012); p. 69 – 71;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: D1 (0.12 g, 0.4 mmol), copper powder (0.032 g, 0.5 mmol), and POP (0.22 g, 0.4 mmol) werereacted in CH3CN (5 mL) at 60 ¡ãC for 24 h. The resulting mixture was filtered through a plugof Celite and concentrated to 1 mL. Addition of Et2O (10 mL) to the filtrate afforded a paleyellow precipitate, which was collected, washed with Et2O, and recrystallized with ethanol., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Liu, Shaobo; Xu, Shengxian; Wang, Jinglan; Zhao, Feng; Xia, Hongying; Wang, Yibo; Journal of Coordination Chemistry; vol. 70; 4; (2017); p. 584 – 599;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: 1.0 mmol of [Cu(CH3CN)4]BF4 and2.0 mmol of PPh3 were dissolved in 10 mL of CH2Cl2. The mixture was refluxed for 30 min at room temperature. Then 1.0 mmol of Phen was added. The mixture was refluxed for another half hour.The solvent was removed by rotary evaporation. The crude product was further purified by recrystallization from the mixed solvent of tetrahydrofuran/ether. Yield: 85percent., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Zhang, Kai; Zhang, Dong; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 124; (2014); p. 341 – 348;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.63995-70-0,Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate,as a common compound, the synthetic route is as follows.,63995-70-0

Example 1 15.5 g of 2-chloroacetophenone, 31.3 g of 4′-n-pentoxybiphenyl-4-boronic acid, 7.5 g of sodium carbonate and a mixture of 44 mg of palladium as a 22% strength aqueous chloride solution, 1 ml of water and 720 mg of a 0.6M aqueous TPPTS solution together with 120 ml of ethylene glycol and 16 ml of water are placed under nitrogen in a reaction vessel and heated to boiling for 4 hours. After cooling to room temperature, 150 ml of water are added, the mixture is stirred vigorously for another 20 minutes and the solid which remains is filtered off. Crystallization of the residue from acetone and drying at 50 C. under reduced pressure gives 32 g (89%) of 2-(4′-n-pentoxy[1,1′]biphenyl-4-yl)-acetophenone having a melting point of 86 C.

As the paragraph descriping shows that 63995-70-0 is playing an increasingly important role.

Reference£º
Patent; Clariant GmbH; US2001/20104; (2001); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

General procedure: The stoichiometricamounts of [Cu(CH3CN)4](PF6)/Au(THT)Cl, K{S(O)COR} R = CH(CH3)2, CH2CH(CH3)2 and PPh3/dppf/PMe3 were taken in 100 mLround bottom flask containing 30 mL of acetone. The reaction mixturewas stirred at room temperature for 1 h under nitrogen atmosphere.The resultant solution was filtered and was evaporated todryness under vacuum to obtain a white solid. The residue was dissolvedin DCM and washed with water (3 20 mL). Finally theCH2Cl2 was evaporated to dryness under vacuum to yield complexesas fine white powders. The stoichiometry and the amountsof reagents used in each case are given below

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Cyue, Jhih-Yu; Kishore, Pilli V.V.N.; Liao, Jian-Hong; Lin, Yan-Ru; Liu; Inorganica Chimica Acta; vol. 462; (2017); p. 97 – 105;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To suspension of sodium dithiocarbamate 2a-f (0.5 mmol) inCH3OH (10 mL) was added a solution of K2PtCl4 (0.210 g,0.50 mmol) in H2O (10 mL). The reaction mixture wasstirred for 30 min. Next, a solution of dppf (0.28 g, 0.50 mmol)in CH2Cl2 (10 mL) was slowly added to the above mixtureand stirred for 24 h. KPF6 (0.46 g, 2.5 mmol) was addedand the mixture was stirred for another 8 h. The solvent wasthen evaporated, and dichloromethane was added to theresidue and the mixture washed with water. The organicphases were dried over anhydrous Na2SO4. The crude productwas purified by chromatography (eluent: CH2Cl2/CH3OH, 50:1, v/v) to give complexes 3a-f.3a: yellow solid, 0.30 g (Yield: 58%). 1H NMR (500MHz, CDCl3): delta 7.64 (m, 7H, -PhH), 7.56 (t, J = 6.8 Hz,5H, -PhH), 7.48 (t, J = 6.9 Hz, 8H, -PhH), 4.57 (s, 4H,-CpH), 4.38 (d, J = 1.7 Hz, 4H, -CpH), 3.54 (t, J = 7.2 Hz,4H, -NCH2-, -NCH2-), 1.20 (t, J = 7.2 Hz, 6H, -CH2CH3,-CH2CH3). 13C NMR (125 MHz, CDCl3): delta 133.94, 133.89,133.85, 132.29, 129.48, 128.99, 128.94, 128.90, 76.18,74.45, 44.67, 12.39. 31P NMR (200 MHz, CDCl3): delta 15.94,-144.30 (m). ESI-MS(+): m/z found 843.1473 [M-Fe-PF6]+,897.0880 [M-PF6]+, calcd for C39H38F6FeNP3PtS21042.0560.

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Xu, Shou De; Wu, Xiang Hua; Journal of Chemical Research; vol. 43; 9-10; (2019); p. 437 – 442;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

To a solution of AuCl(tht) (417 mg, 1.30 mM) in 70mL methanol was added TPPTS (738.9 mg, 1.30 mM). After being stirred for approximately 40 min, the solution was filtered through Celite and the filtrate was concentrated under vacuum to about 3mL. Addition of diethyl ether precipitated the colorless complex, which was isolated by filtration, washed with diethyl ether, and dried in vacuum. Yield: 1.00 g (95.7%). 1H NMR (D2O): delta 7.54-7.65 (m), 7.87-7.91 (m). 31P{1H} NMR (D2O): delta 33.73 (s).

63995-70-0 Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate 6099338, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Rezsnyak, Chad E.; Autschbach, Jochen; Atwood, Jim D.; Moncho, Salvador; Journal of Coordination Chemistry; vol. 66; 7; (2013); p. 1153 – 1165;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a dichloromethane solution (20 mL) of 1a (20 mg, 0.06 mmol) and dppf (35 mg, 0.06 mmol) was added dropwise a CH2Cl2 solution (10 mL) of Me3NO (5 mg, 0.07 mmol) over a period of 30 min and stirred for an additional 5 h at room temperature. The reaction mixture was then filtered through a short silica column (4 cm). The solvent was removed under reduced pressure and the residue chromatographed by TLC on silica gel. Elution with cyclohexane/dichloromethane (3:7, v/v) developed four bands. The first and second bands were unreacted dppf and phenazine, respectively. The third gave Fe(CO)2) (kappa1-dppf) (eta4-C12H8N2) (5a) (21 mg, 40percent) while the fourth band afforded a trace amount of material insufficient for characterization. Spectral data for 5a: IR (nuCO, CH2Cl2): 1994(vs), 1941(vs) cm-1. 1H NMR (CDCl3): delta 7.43 (m, 20H), 7.23 (m, 4H), 5.91 (m, 2H), 4.45 (m, 2H), 4.22 (m, 2H), 3.86 (m, 2H), 3.70 (m, 2H), 3.06 (m, 2H). 31P{1H} NMR (CDCl3): delta 61.0 (s, 1P) -18.1 (s, 1P). Anal. Calcd. for C48H36Fe2N2O2P2: C, 68.11; H, 4.29; N, 3.31. Found: C, 68.31; H, 4.42; N, 3.46percent.

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Chowdhury, Md. Arshad H.; Rahman, Md. Saifur; Islam, Md. Rakibul; Rajbangshi, Subas; Ghosh, Shishir; Hogarth, Graeme; Tocher, Derek A.; Yang, Li; Richmond, Michael G.; Kabir, Shariff E.; Journal of Organometallic Chemistry; vol. 805; (2016); p. 34 – 41;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate