Tag: M.W:400-500

657408-07-6, Name is Dicyclohexyl(2′,6′-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine, molecular formula is C26H35O2P, belongs to chiral-phosphine-ligands compound, is a common compound. In a patnet, once mentioned the new application about 657408-07-6, COA of Formula: C26H35O2P

Compounds comprising a triphenylene moiety and a benzo- or dibenzo-moiety are provided. In particular, the benzo- or dibenzo-moiety has a fused substituent. These compounds may be used in organic light emitting devices, particularly in combination with yellow, orange and red emitters, to provide devices with improved properties.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.COA of Formula: C26H35O2P. In my other articles, you can also check out more blogs about 657408-07-6

Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Reference of 97239-80-0, An article , which mentions 97239-80-0, molecular formula is C22H28FeP2. The compound – 1,1′-Bis(diisopropylphosphino)ferrocene played an important role in people’s production and life.

The reactivity of [{(Ph2PC6H4) 2B(eta6-Ph)}RuCl][B(C6F5) 4] (1) as a Lewis acid was investigated. Treatment of 1 with mono and multidentate phosphorus Lewis bases afforded the Lewis acid-base adducts with the ortho-carbon atom of the coordinated arene ring. Similar reactivity was observed upon treatment with N-heterocyclic carbenes; however, adduct formation occurred at both ortho- and para-carbon atoms of the bound arene with the para-position being favoured by increased steric demands. Interestingly treatment with isocyanides resulted in adduct formation with the B-centre of the ligand framework. The hydride-cation [{(Ph2PC6H 4)2B(eta6-Ph)}RuH] [B(C6F 5)4] was prepared via reaction of 1 with silane. This species in the presence of a bulky phosphine behaves as a frustrated Lewis pair (FLP) to activate H2 between the phosphorus centre and the ortho-carbon atom of the eta6-arene ring.

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Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Electric Literature of 564483-19-8. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 564483-19-8, Name is Di-tert-butyl(2′,4′,6′-triisopropyl-[1,1′-biphenyl]-2-yl)phosphine

A novel 4-aminoindazole sulfonamide hit (13) was identified as a human CCR4 antagonists from testing a focussed library of compounds in the primary GTPgammaS assay. Replacing the indazole core with a pyrazolopyrimidine, and introduction of a methoxy group adjacent to the sulfonamide substituent, resulted in the identification of pyrazolopyrimidine 37a, which exhibited good binding affinity in the GTPgammaS assay (pIC50 = 7.2), low lipophilicity (c log P = 2.2, chromlog D7.4 = 2.4), high LE (0.41), high solubility (CLND solubility ?581 muM), and an excellent PK profile in both the rat (F = 62%) and the dog (F = 100%). Further SAR investigation of the pyrazolopyrimidine suggested that substitution at N1 is tolerated, providing a suitable vector to modulate the properties, and increase the potency in a lead optimisation campaign.

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Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Electric Literature of 13991-08-7, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.13991-08-7, Name is 1,2-Bis(diphenylphosphino)benzene, molecular formula is C30H24P2. In a patent, introducing its new discovery.

The direct cross-coupling of two different electrophiles, such as an aryl halide with an alkyl halide, offers many advantages over conventional cross-coupling methods that require a carbon nucleophile. Despite its promise as a versatile synthetic strategy, a limited understanding of the mechanism and origin of cross selectivity has hindered progress in reaction development and design. Herein, we shed light on the mechanism for the nickel-catalyzed cross-electrophile coupling of aryl halides with alkyl halides and demonstrate that the selectivity arises from an unusual catalytic cycle that combines both polar and radical steps to form the new C-C bond.

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Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Electric Literature of 13991-08-7, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 13991-08-7, C30H24P2. A document type is Article, introducing its new discovery.

The gold(i) complex [Au(dppbO)Cl] was synthesized by reaction of Na[AuCl4]·2H2O with 1,2-bis(diphenylphosphino)benzene (dppb) in the presence of water. This is a new method for the synthesis of a bisphosphine monoxide gold(i) complex. The new gold(i) complex was characterized by NMR spectroscopy and X-ray crystal structure analysis. In the solid state structure a relatively short contact between the oxygen atom of the phosphine oxide group and the gold center was observed. The catalytic activity of [Au(dppbO)Cl] was tested for three different intermolecular alkyne hydrofunctionalization reactions. Silver tetrafluoroborate was used as co-catalyst for halide abstraction. While the bisphosphine monoxide gold(i) complex showed moderate activity for the hydration of various alkynes and the hydroamination of phenyl acetylene, high activity was observed for the hydroarylation of ethylpropiolate. Electron-rich arenes add very fast to the C-C triple bond but with relatively low selectivity.

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Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 1034-39-5, C18H15Br2P. A document type is Article, introducing its new discovery., COA of Formula: C18H15Br2P

Reactions of dihalogenotriorganophosphorus R3PX2 (X = Br or I) with unactivated coarsegrain nickel powder have been investigated.The nature of the nickel phosphine complexes formed is remarkably dependent on both R and X.Where R <*> Me and X = I the nickel(II) complexes are formed, analogous to, but not isostructural with, similar cobalt complexes of the same stoichiometry formed from cobalt powder and R3PI2.Quantitative electronic spectroscopic studies indicated that, surprisingly, the complexes all have predominantly square-planar geometry around nickel.Where R = Me and X = I, the nickel(III) complex is obtained in quantitative yield, the other product being diiodine.Reaction of nickel powder with Me2PhPI2 yields both the nickel(II) complex, , and the nickel(III) complex, .These observations again mirror analogous cobalt reactions.Reaction of the analogous dibromo compounds, R3PBr2, with nickel powder is extremely sensitive to the nature of R.Where R = Me, Et or Pnn no reaction occurs; where R3 = PhMe2 the square-planar complex and an octahedral complex of stoichiometry Ni(PPhMe2)2Br4 are obtained in equal yield.Where R3 = Ph2Prn the octahedral complex is formed with a trace of the planar complex , and where R = Ph the octahedral complex is formed in quantitative yield.The complex has been crystallographically characterised: monoclinic, space group P21/a, a = 10.018(2), b = 10.249(1), c = 10.138(1) Angstroem and Z = 2 (molecule centrosymmetric).

Interested yet? Keep reading other articles of 1034-39-5!, COA of Formula: C18H15Br2P

Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 19845-69-3, Name is 1,6-Bis(diphenylphosphino)hexane, molecular formula is C30H32P2. In a Article，once mentioned of 19845-69-3, Computed Properties of C30H32P2

Single crystal X-ray structural characterizations are recorded for a number of adducts of MX:dpex (2:3) stoichiometry (MX = simple univalent copper or silver salt; dpex = Ph2E(CH2)xEPh2 (E = P, As)). CuX:dppe (2:3) (X = Cl, Br, I, CN) are binuclear [(dppe-P,P?)CuX(P-dppe-P?)CuX(P,P?-dppe)], all centrosymmetric. AgX:dpex (2:3) (dpex = ‘dpae’ (Ph2As(CH 2)2AsPh2), X = Br, F3CCO2 (= ‘tfa’), F3CSO3 (? ‘tfs’); dpex = ‘dpape’ (Ph2As(CH2)2PPh2), X = CN, SCN, OClO3) are one-dimensional polymers ?-E?) 1AgX(E-dpex-E?)2-AgX(E-dpex-E?) 1AgX?, P, As sites scrambled in the latter. AgNO 3:dpam (2:3) is also a one-dimensional polymer, ?AgO· NO·OAg(As-dpam-As)AgO·NO·OAg? (‘dpam’ ? Ph2As(CH2)2AsPh2). AgX:dpae (2:3) (X = I, CN, ClO4, NO3) and AgX:dpape (2:3) (X = Br, I, NO3) are two-dimensional polymers with large 30-membered macrocyclic rings; similar webs are found for dppx ligands in AgOH:dppb (2:3) and AgNCO, Agtfa:dpph (2:3) with 42- and 54-membered rings. Complexes AgX:dpape (1:3) (X = Cl, Br) are defined as mono-nuclear [XAg(Ph2P(CH2) 2AsPh2)3] arrays, the unidentate ligands predominantly P-bound. Synthetic procedures for the adducts are reported, selected compounds being characterized both in solution (1H, 31P NMR, ESI MS) and in the solid state (IR).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Computed Properties of C30H32P2. In my other articles, you can also check out more blogs about 19845-69-3

Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.564483-18-7, Name is 2-(Dicyclohexylphosphino)-2′,4′,6′-tri-i-propyl-1,1′-biphenyl, molecular formula is C33H49P. In a Patent，once mentioned of 564483-18-7, category: chiral-phosphine-ligands

The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 564483-18-7 is helpful to your research., category: chiral-phosphine-ligands

Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

564483-18-7, Name is 2-(Dicyclohexylphosphino)-2′,4′,6′-tri-i-propyl-1,1′-biphenyl, molecular formula is C33H49P, belongs to chiral-phosphine-ligands compound, is a common compound. In a patnet, once mentioned the new application about 564483-18-7, Computed Properties of C33H49P

Disclosed are compound of Formula (Ia), wherein R1A, R1, R2, R10, J, L, T, X, Y, and Z are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions, comprising one or more compounds of Formula (Ia).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Computed Properties of C33H49P. In my other articles, you can also check out more blogs about 564483-18-7

Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.19845-69-3, Name is 1,6-Bis(diphenylphosphino)hexane, molecular formula is C30H32P2. In a Article，once mentioned of 19845-69-3, Recommanded Product: 19845-69-3

Reaction of polymeric gold(I) acetylide species (bpyC?CAu) n (bpyC?CH = 5-ethynyl-2,2?-bipyridine) with diphosphine ligands Ph2P(CH2)nPPh2 (n = 2-6) or 1,1?-bis(diphenylphosphino)-ferrocene (dppf) in dichloromethane induces isolation of binuclear gold(I) complexes (bpyC?CAu)2{mu- Ph2P(CH2)nPPh2} or (bpyC?CAu)2(mu-dppf). Complexation of Ln(hfac)3 (hfac = hexafluoroacetylacetonate, Ln = Nd, Eu, Er, Yb) subunits to the binuclear gold(I) complexes through 2,2?-bipyridyl chelation gives the corresponding Au4Ln4 or Au2Ln2 heteropolynuclear complexes. Noticeably, upon formation of the Au 4Ln4 arrays by complexation of (bpyC?CAu) 2(mu-Ph2P(CH2)4PPh2) (3) with Ln(hfac)3 units, trans-conformation in 3 transforms dramatically to the cis-arranged form due to the strong driving force from ligand-unsupported Au-Au contacts between two Au2Ln2 subunits. In contrast, cis-conformation in (bpyC?CAu)2(mu- dppf) (6) stabilized by Au-Au interactions is reversed to the trans-oriented form upon formation of Au2Ln2 arrays by introducing Ln(hfac)3 units through 2,2-bipyridyl chelation. The binuclear gold(I) complexes show bright blue luminescence featured by ligand-centered pi ? pi* (C?Cbpy) states together with low-energy emission at 500-540 nm, associated with 3(pi?pi*) excited states, mixed probably with some characteristic from (Au-Au) ? (C?Cbpy) 3MMLCT transition. For Au4Ln4 or Au 2Ln2 complexes, sensitized lanthanide luminescence is achieved by energy transfer from Au-acetylide chromophores with lifetimes in the sub-millisecond range for EuIII complexes, whereas in the microsecond range for near-infrared emitting NdIII, ErIII, and YbIII species.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 19845-69-3, you can also check out more blogs about19845-69-3

Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate