Tag: M.W:200-300

50777-76-9, 2-(Diphenylphosphino)benzaldehyde is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

50777-76-9, In a test cylinder containing a coolant, the molecular sieve 4 is activated. The solution of L(+)-leucine (65.5 mg, 0.5 mmol, 1 eq.) and potassium hydroxide (28 mg, 0.5 mmol, 1 eq.) in degassed anhydrous methanol (2 mL per mmol) is added. Orthodiphenylphosphine-benzaldehyde (145 mg, 0.5 mmol, 1 eq.) is then added and the mixture is kept under vigorous agitation for 3 hours at 40¡ã C. The solvent is then evaporated. The potassium iso-leucine phosphinoazomethinylate (Ib-K) is obtained in the form of a yellowish solid (209 mg, 95percent). The RMN characteristics of this compound are as follows:RMN 1H: (400 MHz, CD3DO) delta (ppm): 8.88 (d, H,PJ=5.5 Hz, 1H, H1); 8.06-8.02 (m, 1H, H9); 7.28-7.07 (m, 12H, H7, H8, H10-19); 6.72-6.69 (m, 1H, H5); 3.70 (dd 2J=4.4 Hz, 2J=9.7 Hz, 1H, H2); 1.55 (qd, 3J=4.4 Hz, 2J=9.7 Hz, 2H, H3); 0.89 (m, 1H, H4); 0.62 (d, 3J=6.6 Hz, 3H, H5′); 0.51 (d, 3J=6.4 Hz, 3H, H5)RMN 31P: (162 MHz, CD3DO) delta (ppm): -14.59 (s, 1P)RMN 13C: (100 MHz, CD3DO) delta (ppm): 180.90 (10, C20); 161.59 (1C, C1); 141.42 (1C, C21); 139.32 (1C, C24); 139.13 (10, C23); 138.0 (10, C6); 137.74 (1C, C22); 135.8 (4C, C10,14,15,19) 134.33 (1C, C9); 131.87-129.13 (8C, C7,8,11-13,166-18); 76.94 (1C, C2); 44.54 (10, C4); 25.7 (1C, C5); 24.3 (1C, C5′); 21.9 (1C, C3)

As the paragraph descriping shows that 50777-76-9 is playing an increasingly important role.

Reference£º
Patent; Mauduit, Marc; Rix, Diane; Crevisy, Christophe; Wencel, Joanna; US2010/267956; (2010); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1079-66-9,Chlorodiphenylphosphine,as a common compound, the synthetic route is as follows.

To an ice-cold solution of methyl alcohol (6 mL, 1.2 mmol) in toluene (13 mL), a solution of chlorodiphenylphosphine (0.25 mL, 1.38 mmol) in toluene (3 mL) was added dropwise. After 40 min stirring, azide 5 (440 mg, 1.2 mmol) was added as a solid. The obtained mixture was heated at 60 C for 40 min and then kept at room temperature for 12 h. The collected precipitate was analytically pure product 6 (300 mg, 48%). Crystals suitable for X-ray diffraction were obtained by crystallization from MeCN-DMF (3 : 1). M.p. 245 C. Found (%): P, 5.66. C27H21BrN3O2. Calculated (%): P, 5.70. IR (KBr), nu/cm-1: 1706 (C=O), 1606 (C=N), 3346 (NH). 31P NMR (DMSO-d6), delta: 23.45. 1H NMR (DMSO-d6), delta: 4.72-4.76 (m, 1 H, CHNP); 6.43-7.97 (m, 8 H, Ar); 11.01 (s, 1 H, NH).

1079-66-9, 1079-66-9 Chlorodiphenylphosphine 66180, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Gololobov, Yu. G.; Krasnova, I. Yu.; Barabanov; Fedyanin; Andronati; Pavlovskii; Russian Chemical Bulletin; vol. 64; 1; (2015); p. 233 – 236; Izv. Akad. Nauk, Ser. Khim.; 1; (2015); p. 233 – 236,4;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7650-91-1,Benzyldiphenylphosphine,as a common compound, the synthetic route is as follows.

7650-91-1, A mixture of Fe2(l-pdt)(CO)6 (0.097 g, 0.25 mmol), Ph2P(CH2Ph) (0.083 g, 0.3 mmol) and Me3NO2H2O (0.034 g, 0.3 mmol) was dissolved in MeCN (15 mL). The mixture was stirred at room temperature for 0.5 h to give a brown-red solution. The solvent was removed on a rotary evaporator and the residue was subject to preparative TLC separationusing CH2Cl2/petroleum ether (v/v1:5) as eluent. From the main red band, 1(0.076 g, 48%) was obtained as a red solid. Anal. Calcd for C27H23Fe2O5PS2: C, 51.13; H,3.66%. Found: C, 50.95; H, 3.87%. FT-IR (KBr disk, cm-1): mCO 2041 (vs.), 1979 (vs.),1954 (s), 1922 (m). 1H NMR (600 MHz, CDCl3, TMS, ppm): 7.68 (s, 4H, 2xPPhH-o), 7.44 (s,6H, 2xPPhH-m,p), 7.17 (s, 1H, CH2PhH-p), 7.11 (s, 2H, CH2PhH-o), 6.71 (s, 2H, CH2PhHm),3.87 (s, 2H, CH2Ph), 1.86 (s, 2H, 2xSCHeHa), 1.65-1.51 (m, 2xSCHeHa and CH2).31P{1H} NMR (243 MHz, CDCl3, 85% H3PO4, ppm): 63.14 (s).

As the paragraph descriping shows that 7650-91-1 is playing an increasingly important role.

Reference£º
Article; Zhao, Pei-Hua; Ma, Zhong-Yi; Hu, Meng-Yuan; Jing, Xing-Bin; Wang, Yan-Hong; Liu, Xu-Feng; Journal of Coordination Chemistry; vol. 71; 16-18; (2018); p. 2941 – 2952;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13689-19-5, Tricyclohexylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The same general procedure was adopted for the synthesis of all the complexes. The lanthanide bromide and tricyclohexylphosphineoxide were dissolved in hot ethanol. Heating was continued for 1 h during which time, in some cases, small quantities of crystalline material formed. Either cooling to room temperature followed by standing for 16 h or on prolonged standing and slow evaporation of the solution afforded crystalline materials. The crystals were filtered, washed with ethanol and dried at the pump. Representative syntheses and characterisations are described below.

13689-19-5, As the paragraph descriping shows that 13689-19-5 is playing an increasingly important role.

Reference£º
Article; Bowden, Allen; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 91; (2015); p. 110 – 119;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.24171-89-9,Tri(thiophen-2-yl)phosphine,as a common compound, the synthetic route is as follows.

2-Chloromethyl-3-hydroxypyridine hydrochloride (4) (0.40 g, 2.22 mmol) was added to a solution of tris- (2-thienyl)phosphine (0.93 g, 3.32 mmol) in acetonitrile (40 mL) and the mixture was refluxed for 12 h. Then, the solvent was evaporated in vacuo, the dry residue was dissolved in chloroform and washed with water. The aqueous layer was separated, dried in vacuo, and recrystallized from acetone. The yield was 0.24 g (24%), a white crystalline compound, m.p. 197-198 C. 1H NMR (DMSO-d6), d: 5.29 (d, 2 H, CH2P, J = 14.4 Hz); 7.22 (ABX-system, 1 H, 5-PyH, J1 = 8.0 Hz, J2= 4.6 Hz); 7.34 (ABX- system, 1 H, 4-PyH, J = 8.0 Hz); 7.49 (m, 3 H, P(2-thien)3 (thien means thienyl)); 7.91 (ABX-system, 1 H, 6-PyH, J = = 4.6 Hz); 7.97 (dd, 3 H, P(2-thien)3, J1 = 8.3 Hz, J2 = 3.4 Hz); 8.45 (t, 3 H, P(2-thien)3, J = 4.6 Hz); 10.83 (s, 1 H, OH). 13C NMR (DMSO-d6), d: 32.92 (d, CH2P, J = 64.3 Hz); 120.00 (d, Cthien, J = 112.2 Hz); 122.70 (s, CPyr); 124.62 (s, CPyr); 129.99 (d, Cthien, J = 16.2 Hz); 137.83 (d, Cthien, J = 3.9 Hz); 138.53 (s, CPyr); 140.51 (d, Cthien, J = 4.1 Hz); 141.98 (d, CPyr, J = 12.1 Hz); 152.36 (d, CPyr, J = 8.0 Hz). 31P NMR (DMSO-d6), d: 10.68. HRMS, found: m/z 388.0048 [M – 2 Cl – H]+. C18H16NOPS3Cl2. Calculated: [M – 2 Cl – H] = 388.0048., 24171-89-9

The synthetic route of 24171-89-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Shtyrlin; Vafina; Pugachev; Khaziev; Nikitina; Zeldi; Iksanova; Shtyrlin, Yu. G.; Russian Chemical Bulletin; vol. 65; 2; (2016); p. 537 – 545; Izv. Akad. Nauk, Ser. Khim.; 2; (2016); p. 537 – 545,9;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.932710-63-9,4-(Di-tert-butylphosphino)-N,N-dimethylaniline,as a common compound, the synthetic route is as follows.

932710-63-9, Take a dry 10L three-neck reaction flask, dry nitrogen is fully replaced and under nitrogen flow protection,Add 5.5 L of anhydrous tetrahydrofuran, stir and add 540 g of bis(acetonitrile)palladium dichloride.The obtained ligand di-tert-butyl-4-dimethylaminophenylphosphine was further reacted for 30 minutes, and a yellow solid was precipitated. After the reaction was continued for 9 hours at room temperature,After filtration, the filter cake was dipped in anhydrous tetrahydrofuran, drained and dried in a vacuum oven at 60 C.Obtaining a yellow crystalline powdery target product, namely dichlorodi-tert-butyl-(4-dimethylaminophenyl)phosphine palladium, yielding 1440 g to 1445 g,Elemental analysis showed that the product content exceeded 98.0%, the palladium content exceeded 15.0%, and the palladium calculated yield was 97.7% to 98.1%.

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

Reference£º
Patent; Shanxi Ruike New Materials Co., Ltd.; Zhang Wen; Zhao Lei; Hou Yunji; Cai Wanyu; (11 pag.)CN108659054; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

1079-66-9, Chlorodiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 1 330 g (7.17 mol) of absolute ethanol are cooled to -15 C. under a nitrogen atmosphere. 26.5 g (1.56 mol) of ammonia gas are introduced thereto at this temperature with constant stirring. 200 g (0.907 mol) of chloro(diphenyl)-phosphine are then added dropwise at this temperature. The mixture is then allowed to come to room temperature with stirring and is then kept under reflux for 11 hours until virtually no more ammonia gas escapes. The mixture is then cooled, filtered by suction, washed with ethanol and dried. 48 g of crude ammonium chloride are obtained. The filtrate is freed from ethanol and any ammonia present in vacuo. The remaining residue is freed from a slight salt precipitate by filtration through a glass frit. 170 g of ethyl diphenylphosphinite are then obtained by thin film distillation at a bath temperature of 160 to 175 C. and a pressure of 0.5 mbar. This corresponds to a yield of 82% of theory., 1079-66-9

As the paragraph descriping shows that 1079-66-9 is playing an increasingly important role.

Reference£º
Patent; Hoechst Aktiengesellschaft; US5705669; (1998); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13689-19-5,Tricyclohexylphosphine oxide,as a common compound, the synthetic route is as follows.

General procedure: The same general procedure was adopted for the synthesis of all the complexes. The lanthanide bromide and tricyclohexylphosphineoxide were dissolved in hot ethanol. Heating was continued for 1 h during which time, in some cases, small quantities of crystalline material formed. Either cooling to room temperature followed by standing for 16 h or on prolonged standing and slow evaporation of the solution afforded crystalline materials. The crystals were filtered, washed with ethanol and dried at the pump. Representative syntheses and characterisations are described below.

13689-19-5, The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Bowden, Allen; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 91; (2015); p. 110 – 119;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50777-76-9,2-(Diphenylphosphino)benzaldehyde,as a common compound, the synthetic route is as follows.

50777-76-9, General procedure: To a mixture of 2-(diphenylphosphino)benzaldehyde(500 mg, 1.72 mmol) and the appropriate amine(1.81 mmol) was added formic acid (1 drop) in MeOH(5 mL). The reaction was allowed to proceed at RT for18 h, at which point the iminophosphine pro-ligand was collected by suction filtration as a pale yellow precipitate. Spectroscopic NMR data were collected in CDCl3 as the pro-ligands decompose in wet DMSO-d6. The spectroscopically pure pro-ligands were used as prepared to make the corresponding platinum(II) complexes.

As the paragraph descriping shows that 50777-76-9 is playing an increasingly important role.

Reference£º
Article; St-Coeur, Patrick-Denis; Adams, Meghan E.; Kenny, Bryanna J.; Stack, Darcie L.; Vogels, Christopher M.; Masuda, Jason D.; Morin, Pier Jr.; Westcott, Stephen A.; Transition Metal Chemistry; vol. 42; 8; (2017); p. 693 – 701;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50777-76-9,2-(Diphenylphosphino)benzaldehyde,as a common compound, the synthetic route is as follows.

50777-76-9, General procedure: To a dichloromethane solution (15 mL) of 2-diphenylphosphinobenzaldehyde (ca. 3 mmol) was added an equimolar amount of the appropriate substituted amine. An excess of magnesium sulphate was also added to the reaction mixture to remove the water by-product. The reaction was left to stir at room temperature for 16 h, after which time the magnesium sulphate was filtered off and the solvent removed from the filtrate in vacuo to give a yellowe orange oil. The oily crude products of ligands 1a-1f were solidified by dissolving the oil in hot hexane, followed by quick hot filtration of the liquid product. The resultant solution was then cooled at -16 ¡ãC overnight to give an off-white powder, which was filtered and dried in vacuo.

As the paragraph descriping shows that 50777-76-9 is playing an increasingly important role.

Reference£º
Article; Mogorosi, Mokgolela M.; Mahamo, Tebello; Moss, John R.; Mapolie, Selwyn F.; Slootweg, J. Chris; Lammertsma, Koop; Smith, Gregory S.; Journal of Organometallic Chemistry; vol. 696; 23; (2011); p. 3585 – 3592;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate