Tag: M.W:200-300

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.224311-51-7,2-(Di-tert-Butylphosphino)biphenyl,as a common compound, the synthetic route is as follows.

50 ml entgastes, wasserfreies Methanol wurde auf Rueckflusstemperatur erhitzt, 2,36 g (7,9 mmol) 2-(Di-tert.-butylphosphino)biphenyl wurde langsam dem Methanol zugegeben, bis die Phosphin-Verbindung vollstaendig geloest war. Anschliessend wurde 0,59 g (2,6 mmol) Kupfer(II)-bromid portionsweise der Loesung zugegeben. Nach Zugabe des Kupferbromids wurde die Loesung noch weitere 15 min lang auf Rueckflusstemperatur erhitzt und danach die Loesung abgekuehlt. Nach Abkuehlen der Loesung fiel ein Feststoff aus, der abfiltriert wurde und mit wenig Ethanol und Diethylether gewaschen und anschliessend getrocknet wurde. Man erhielt 0,93 g (1,1 mmol) der oben genannten Verbindung. Die Ausbeute betrug 80 percent d. Th.

224311-51-7, 224311-51-7 2-(Di-tert-Butylphosphino)biphenyl 2734215, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Bayer Aktiengesellschaft; EP1437340; (2004); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

24171-89-9, Tri(thiophen-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a solution of [Fe2(CO)6(mu-SCH2CH2S)] (0.037 g, 0.1 mmol) and tricyclohexylphosphine (0.028 g, 0.1 mmol) in CH2Cl2 (5 mL) was added a solution of Me3NO¡¤2H2O (0.011 g, 0.1 mmol) in MeCN (5 mL). The mixture was stirred at room temperature for 1 h, and then, the solvent was reduced on a rotary evaporator. The residue was subjected to TLC using CH2Cl2/petroleum ether = 1:3 (v/v) as eluent. From the main red band, 0.042 g (68%) of complex 2 was obtained as a red solid., 24171-89-9

The synthetic route of 24171-89-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Yan, Lin; Li, Ao; Xiao, Qi-Min; Liu, Xu-Feng; Li, Yu-Long; Jiang, Zhong-Qing; Wu, Hong-Ke; Transition Metal Chemistry; vol. 44; 5; (2019); p. 483 – 489;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

7650-91-1, Benzyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

7650-91-1, General procedure: The following procedure was used in place of the general procedure for this reaction: SiO2 (0.0561 g) and di-(mu-acetato)bis-{2-[(N,N-dimethylamino)methyl]phenyl-C,N}dipalladium(II) 1a (0.0222 g, 0.0370 mmol) were mixed first in a small round-bottomed flask. A stir bar was inserted and the flask, septum, and stirring spatula were all transferred to a glove box with an atmosphere of N2. Benzyldiphenylphosphine 7 (0.020 g, 0.072 mmol) was then added to the flask and thoroughly mixed with the spatula. The reaction was allowed to stir at room temperature in the glove box. The flask was capped with the septum before being removed from the glove box and put in a preheated oil bath (100 C) for 2 h. No CaCl2-filled syringe was used in this reaction. The reaction mixture was filtered into a flask with LiCl as described in the general procedure and purified using preparative TLC in CH2Cl2.

The synthetic route of 7650-91-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Lamb, Jessica R.; Stepanova, Valeria A.; Smoliakova, Irina P.; Polyhedron; vol. 53; (2013); p. 202 – 207;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

4020-99-9, Methoxydiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Compound 1 (0.153 mmol) was dissolved in 30 ml of hexane and 2 equivalents of the phosphine (61.8 mg, 0.30 mmol) was added. Thesolution was stirred for 60 min. The reaction mixture was taken to dryness under vacuum and the residue separated by thin layer chromatography using hexane:methylene chloride (4:1) as eluant. Compound 4e. Yellow solid. IR (CH2Cl2, nuCO, cm-1):2076(m), 2052(s), 2040(w), 2012(vs), 1997(s), 1984(w). NMR (CDCl3): delta 1H:-21.59 (d, 3JPH=2.7 Hz, M-H-M), 0.31 (s, SiMe3), 3.56 (s, P(OMe)Ph2),7.41-7.7 (m, P(OMe)Ph2); delta 31P{H}: 119.7; delta 29Si{1H}:1.69., 4020-99-9

The synthetic route of 4020-99-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Gonzalez-Lopez, Vianney; Torres-Sandoval, Indira; Carrasco-Gonzalez, Ana L.; Elias-Jimenez, Adonay; Leyva, Marco A.; Rosales-Hoz, Maria J.; Cruz-Borbolla, Julian; Zuno-Cruz, Francisco J.; Sanchez-Cabrera, Gloria; Jardinez, Christian; Inorganica Chimica Acta; vol. 492; (2019); p. 8 – 17;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

791-28-6, Triphenylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1. Hydrogenation of Triphenylphosphine Oxide; A mixture of triphenylphosphine oxide (707 g, 2.54 mol) and a suspension of ruthenium(IV) oxide hydrate (supported on aluminum oxide) (140 g, comprises 3 g of ruthenium) in tetrahydrofuran (2 l) was hydrogenated at from 120 to 150 C. and a hydrogen pressure of 250 bar with stirring. After cooling to room temperature, the catalyst was filtered off and the filtrate was freed of the solvent under reduced pressure. Distillation of the residue at from 200 to 210 C. (1 mbar) afforded 722 g (96% of theory) of tricyclohexylphosphine oxide in the form of a white solid., 791-28-6

The synthetic route of 791-28-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Basf SE; US2010/137643; (2010); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4020-99-9,Methoxydiphenylphosphine,as a common compound, the synthetic route is as follows.

General procedure: Using the same stoichiometric ratio than in the previous reactions, the hexane solution was stirred at room temperature for 5 days. Then 5 mL of ethanol were added and the solution stirred for another 5 days. The solvent was then evaporated under vacuum and the residue purifiedby TLC. Compound 8d was obtained in 63% yield.

4020-99-9, As the paragraph descriping shows that 4020-99-9 is playing an increasingly important role.

Reference£º
Article; Gonzalez-Lopez, Vianney; Torres-Sandoval, Indira; Carrasco-Gonzalez, Ana L.; Elias-Jimenez, Adonay; Leyva, Marco A.; Rosales-Hoz, Maria J.; Cruz-Borbolla, Julian; Zuno-Cruz, Francisco J.; Sanchez-Cabrera, Gloria; Jardinez, Christian; Inorganica Chimica Acta; vol. 492; (2019); p. 8 – 17;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

607-01-2, Ethyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Compound 1a (30mg, 0.026mmol) and PPh3 (13mg, 0.052mmol) were added together in acetone (15cm3). The mixture was stirred for 24, and after concentration the resulting precipitate was filtered off and recrystallised from dichloromethane/hexane. Yield: 54.35%. Found C: 61.3, H: 4.8; N: 1.9; C42H41NClFeO2PPd (820.47g/mol) requires C: 61.5, H: 5.0, N: 1.7. IR numax/cm-1: 1598m (C=N), 308b (Pd-Cl). NMR 1H (CDCl3): deltaH=8.39 (d, 1H, HC=N, 4J(PH) 8.8) 6.88 (b, 2H, C6H2), 5,41 (s, 1H, CHO2), 4.28 [d, 1H, H3, 3J 2.4Hz], 4.14, 3.86, 2.08, 1.34 (m, 6H, CH2), 3.98 (s, 5H, C5H5), 3.35 [d, 1H, H4, 3J 2.4Hz], 2.46 (s, 3H, Me), 2.28 (s, 3H, Me), 2.26 (s, 3H, Me). NMR 31P (CDCl3): deltaP=36.4 s.

607-01-2, The synthetic route of 607-01-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Martinez, Javier; Marino, Marta; Caamano, Marcelo; Teresa Pereira, Ma; Ortigueira, Juan M.; Gayoso, Eduardo; Lopez-Torres, Margarita; Vila, Jose M.; Journal of Organometallic Chemistry; vol. 740; (2013); p. 92 – 97;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

50777-76-9, 2-(Diphenylphosphino)benzaldehyde is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

50777-76-9, General procedure: To a dichloromethane solution (15 mL) of 2-diphenylphosphinobenzaldehyde (ca. 3 mmol) was added an equimolar amount of the appropriate substituted amine. An excess of magnesium sulphate was also added to the reaction mixture to remove the water by-product. The reaction was left to stir at room temperature for 16 h, after which time the magnesium sulphate was filtered off and the solvent removed from the filtrate in vacuo to give a yellowe orange oil. The oily crude products of ligands 1a-1f were solidified by dissolving the oil in hot hexane, followed by quick hot filtration of the liquid product. The resultant solution was then cooled at -16 ¡ãC overnight to give an off-white powder, which was filtered and dried in vacuo.

As the paragraph descriping shows that 50777-76-9 is playing an increasingly important role.

Reference£º
Article; Mogorosi, Mokgolela M.; Mahamo, Tebello; Moss, John R.; Mapolie, Selwyn F.; Slootweg, J. Chris; Lammertsma, Koop; Smith, Gregory S.; Journal of Organometallic Chemistry; vol. 696; 23; (2011); p. 3585 – 3592;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13689-19-5, Tricyclohexylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The same general procedure was adopted for the synthesis of all the complexes. The lanthanide bromide and tricyclohexylphosphineoxide were dissolved in hot ethanol. Heating was continued for 1 h during which time, in some cases, small quantities of crystalline material formed. Either cooling to room temperature followed by standing for 16 h or on prolonged standing and slow evaporation of the solution afforded crystalline materials. The crystals were filtered, washed with ethanol and dried at the pump. Representative syntheses and characterisations are described below.

13689-19-5, 13689-19-5 Tricyclohexylphosphine oxide 26187, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Bowden, Allen; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 91; (2015); p. 110 – 119;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

7650-91-1,7650-91-1, Benzyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Weigh benzyl diphenylphosphine (138.2 g, 0.5 mol), dimethyl carbonate (135.1 g, 1.5 mol),Benzene (68.3 g, 25%) and 80%-Cs2O/SiO2 catalyst (1.37 g, 0.5%) were added to a stainless steel autoclave,The air in the reaction vessel was replaced by N2, and the temperature was raised to 160 C for 8 hours.After completion of the reaction, the cooling water was cooled to 65 C, and the catalyst was recovered by filtration, and the unreacted raw materials and solvent were distilled off under reduced pressure.The product was washed with n-hexane and then dried under vacuum at 60 C for 5 hours to give benzyldiphenylmethylmethyl carbonate (164.9 g) in a yield of about 90%.The methyl carbonate quaternary phosphonium salt benzyl diphenyl methyl carbonate hydrazine (55.0 g, 0.15 mol) was weighed and dissolved in dichloromethane (137.5 g).Trifluoromethanesulfonic acid (22.5 g, 0.15 mol) was added, and the mixture was refluxed under magnetic stirring at 50 C for 3 hours.After completion of the reaction, the solvent was removed by distillation under reduced pressure to give 62.8 g of benzyldiphenylmethyltrifluoromethanesulfonate ionic liquid, yield of about 95%.

7650-91-1 Benzyldiphenylphosphine 603920, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; China Daily Expenses Chemical Institute Co., Ltd.; Geng Tao; Duan Shengfu; Jiang Yajie; Ju Hongbin; Wang Yakui; (8 pag.)CN108440595; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate