Tag: M.W:200-300

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13689-19-5,Tricyclohexylphosphine oxide,as a common compound, the synthetic route is as follows.

General procedure: The same general procedure was adopted for the synthesis of all the complexes. The lanthanide bromide and tricyclohexylphosphineoxide were dissolved in hot ethanol. Heating was continued for 1 h during which time, in some cases, small quantities of crystalline material formed. Either cooling to room temperature followed by standing for 16 h or on prolonged standing and slow evaporation of the solution afforded crystalline materials. The crystals were filtered, washed with ethanol and dried at the pump. Representative syntheses and characterisations are described below.

13689-19-5, As the paragraph descriping shows that 13689-19-5 is playing an increasingly important role.

Reference£º
Article; Bowden, Allen; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 91; (2015); p. 110 – 119;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13689-19-5, Tricyclohexylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: In a sealed tube containing a solution of the phosphine oxide derivative (5 mmol) in anhydrous toluene (1 M) was added InBr3 (1 mol %, 0.05 mmol) and the TMDS (1.5 equiv, 7.5 mmol) under an argon atmosphere. The reaction mixture was stirred at 100 C during 7-40 h depending on the substrate (the reaction was monitored by 31P NMR). After complete consumption of the reagent the mixture was kept under argon in the sealed tube and cooled to 0 C. A solution of BH3.SMe2 (2 M in THF, 1 equiv) was then slowly added. After 1 h at room temperature, 31P NMR analysis of an aliquot indicates complete conversion to phosphine borane adduct. The crude was poured in an erlenmeyer flask and silica gel was carefully added while stirring. When silica gel was added in the reaction mixture, a slightly exothermic reaction was observed. The reaction mixture was then filtered on silica gel and washed several times with ethyl acetate. After evaporation of the ethyl acetate, the residue was purified by flash chromatography on silica gel with pure cyclohexane to afford the desired phosphine-borane.

13689-19-5, As the paragraph descriping shows that 13689-19-5 is playing an increasingly important role.

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Article; Pehlivan, Leyla; Metay, Estelle; Delbrayelle, Dominique; Mignani, Gerard; Lemaire, Marc; Tetrahedron; vol. 68; 15; (2012); p. 3151 – 3155;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6372-42-5,Cyclohexyldiphenylphosphine,as a common compound, the synthetic route is as follows.,6372-42-5

General procedure: Under N2 atmosphere, NaOAc (4.0 equiv), PPh3 1a (0.5 mmol), PdCl2 (10.0 mol %), AgOOCCF3 (5.0 equiv), CH3CN (2.0 mL) and methyl acrylate 2a (0.6 mmol) were successively added into a Schlenk reaction tube. Then the mixture was stirred at 60 C for 24 h. After cooling to room temperature, the solvent was evaporated in vacuo and then purified by flash column chromatography on silica gel to give the pure product 3a.

As the paragraph descriping shows that 6372-42-5 is playing an increasingly important role.

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Article; Ma, Ming-Tao; Lu, Jian-Mei; Tetrahedron; vol. 69; 9; (2013); p. 2102 – 2106;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

50777-76-9, 2-(Diphenylphosphino)benzaldehyde is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The synthesis of the iminophosphine ligand carryingalkoxylsilane moiety (A) was performed through the reactivedistillation of 2-(diphenylphosphino)benzaldehyde (0.500 g)with 3-(aminopropyl)trimethoxysilane (0.255 g) in dry toluene(25 mL). After 5 hours, we obtained a yellow oily liquidby careful removal of toluene under vacuum (87 percent yield).1H NMR (400 MHz, CD2Cl2): delta = 8.8 (s, 1H), 8.02 (s,1H), 7.45-7.27 (m, 12 H), 6.91 (s, 1 H), 3.53 (s, 9 H), 3.46(m, 2 H), 1.68 – 1.60 (m, 2 H), 0.58 – 0.52 (m, 2 H); 13CNMR (100 MHz, CD2Cl2): delta= 158.57, 134.14, 128.79, 65.13,50.82, 24.62, 8.73 ppm.; 31P NMR : (300 MHz, CD2Cl2,ppm) delta= -13.07ppm., 50777-76-9

The synthetic route of 50777-76-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Upadhyay, Praveenkumar R.; Srivastava, Vivek; Letters in Organic Chemistry; vol. 13; 5; (2016); p. 380 – 387;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50777-76-9,2-(Diphenylphosphino)benzaldehyde,as a common compound, the synthetic route is as follows.

To a solution of 2-(diphenylphosphino)benzaldehyde (0.279 g, 0.961 mmol) in CH2Cl2 (10 ml) in a Schlenk tube was added 2-methylaniline (0.103 g, 0.961 mmol) dropwise. Anhydrous magnesium sulfate (~ 0.5 g) was added to the Schlenk tube and the reaction was stirred at room temperature for 20 h. The resulting yellow mixture was filtered to obtain a yellow solution, which gave yellow oil upon evaporation of the solvent. Yield: 0.2990 g (82percent); IR (nujol cm? 1); nu(C=N imine) 1622, nu(C=C phenyl) 1593, 1585, 1505; nu(P?Ph) 1435; 1H NMR (200 MHz, CDCl3): delta 8.99 (d, 1H, J = 5.2, ?CH=N); 8.27, 6.91?7.67 (m, 12H, phenyl); 6.46 (t, 6H, J = 7.6, phenyl); 1.27 (s, 3H,CH3); 31P NMR (161.9 Hz, CDCl3) delta ? 13.96(s); Anal. Calcd for C26H22NP: C, 82.30; H, 5.84; N, 3.69; Found: C, 82.04; H, 5.93; N, 3.55., 50777-76-9

Big data shows that 50777-76-9 is playing an increasingly important role.

Reference£º
Article; Motswainyana, William M.; Onani, Martin O.; Madiehe, Abram M.; Saibu, Morounke; Thovhogi, Ntevheleni; Lalancette, Roger A.; Journal of Inorganic Biochemistry; vol. 129; (2013); p. 112 – 118;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

607-01-2, Ethyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To acetone solution of (diphenylphosphino) ethane (dppe) (0.398 g, 1 mmol) was added 4-nitrophenacyl bromide (0.256 g, 1.05 mmol)and the resulting mixture was stirred for 12 h at room temperature. The resulting yellow solution was filtered off, washed with petroleum diethyl ether, and dried under vacuum. Yield: 0.49 g, 75%; m. p.:220-222 C. Anal. Calc. for C34H30BrNO4P2: C, 62.02; H, 4.59; N, 2.13. Found: C, 62.27; H, 4.61; N, 2.15%. Selected IR absorption in KBr (cm-1): 1684 (nuC=O), 1191 (nuP=O). 31P{1H} NMR (CDCl3): deltaP = 19.45 (d, PCH2, 3JPP = 58.37); 31.66 (d, P(O)Ph2, 3JPP = 54.82). 1H NMR (CDCl3): deltaH = 2.83 (m, 2H, CH2); 3.82 (m, 2H, CH2); 6.32 (d, 1H, PCH2CO, 2JPH = 12.25), 6.52 (d, 1H, PCH2CO, 2JPH = 12.00); 7.18-8.37 (m, 24H, Ph). 13C{1H} NMR (CDCl3): deltaC = 18.06 (t, CH2, 1JPC = 26.03); 36.32 (pseudot, PCH2CO, 1JPC = 29.13); 116.03-134.95 (Ph); 191.31 (s, CO).

607-01-2, Big data shows that 607-01-2 is playing an increasingly important role.

Reference£º
Article; Samiee, Sepideh; Kooti, Nadieh; Gable, Robert W.; Journal of Molecular Structure; vol. 1129; (2017); p. 319 – 324;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

7650-91-1, Benzyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

7650-91-1, In the Ar atmosphere,1.0 mmol of the compound of the structure of the formula (3) (wherein R1 and R2 are each independently hydrogen; synthesized by the method of Organometallics 2008, 27, 88-99) were dissolved in 50 mL of anhydrous THF, and then 1.0 mmol of the azide compound of the structure represented by the formula (4) (R3 is a phenyl group, commercially available from ALDRICH) was added,The reaction was stirred at 15 [deg.] C for 12 hours.The resulting reaction solution was concentrated to about 10 ml,2 mL of n-hexane was added (keeping the solution clear).The mixture was stored at -30 overnight,Precipitation ligand.The resulting solid was filtered,Washed with a small amount of n-hexane,Vacuum drying,To obtain ligand L1.Ligand L1 was analyzed,The results are as follows:

The synthetic route of 7650-91-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Sinopec China Petroleum & Chemical Corporation; Sinopec Beijing Research Institute of Chemical Industry; Sun, Wei; Xin, Yishuang; Shao, Mingbo; Li, Chuanqing; Wang, Xue; Zhao, Jiangwei; (18 pag.)CN105985382; (2016); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50777-76-9,2-(Diphenylphosphino)benzaldehyde,as a common compound, the synthetic route is as follows.

50777-76-9, Under inert gas protection,50 mL of Schlenk reaction tube was added2,9-dimethyl-4,7-bis (2-thienyl) -1,10-phenanthroline (0.187 g, 0.5 mmol)2- (diphenylphosphino) benzaldehyde (0.291 g, 1 mmol) andPotassium carbonate (50 mmol),Add deoxygenated toluene (20 mL)Rose to 100 ¡ã C for 12 h,Cooled to room temperature, 50 mL of water was added to the reaction solution, the solid was precipitated and filtered,The filtered solid was recrystallized from 1 mL of crystalline solvent methanol,To give the title product 335 mg, yield 73percent

As the paragraph descriping shows that 50777-76-9 is playing an increasingly important role.

Reference£º
Patent; Zhejiang University of Technology; Luo Shuping; Yu Zhejian; Chen Hao; Xia Liangmin; Wang Mingming; Wu Qingan; (8 pag.)CN106749411; (2017); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4020-99-9,Methoxydiphenylphosphine,as a common compound, the synthetic route is as follows.

To 100ml round-bottomed flask protected from light with aluminum foil, 3-isocyanato-2,4,6-trimethylbenzoyl chloride 3.0 g (13.4mmol) was taken, and after depressurization and purged with nitrogen, dry tetrahydrofuran 50ml was added and dissolved. To this solution, methoxydiphenylphosphine2.7ml (13mmol) was dropped at 65C , and the mixture was stirred for 1.5 hours. The solvent was evaporated under reduced pressure, azeotroped twice with hexane 50ml, and dried under reduced pressure, to give 3-isocyanato-2,4,6-trimethylbenzoyldiphenylphosphineoxidecrude product 5.5g. To 100ml round-bottomed flask protected from light with aluminum foil, methanol 20ml was taken, and after decompression and purged with nitrogen, the mixture was stirred at 40C. Here, 3-isocyanato-2,4,6-trimethylbenzoyldiphenylphosphineoxidecrude product 1.0g was added over 5 min to asolution dissolved in tetrahydrofuran 5ml under nitrogen atmosphere, and stirred at 40 C for 5 hours. After evaporation of the solvent under reduced pressure, under protection from light, it was purified by silica gel column chromatography to give the objective compound 1.0g (97% yield)., 4020-99-9

The synthetic route of 4020-99-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; KurarayNoritakeDentalCo., Ltd.; Tsuruta, Takahiro; Ishino, Hiroshige; (33 pag.)JP5688933; (2015); B2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.24171-89-9,Tri(thiophen-2-yl)phosphine,as a common compound, the synthetic route is as follows.

A benzene solution (20 mL) of 1 (30 mg, 0.054 mmol) and PTh3 (15 mg, 0.054 mmol) was refluxed for 12 h. The solvent was removed under reduced pressure and the residue chromatographed by TLC on silica gel. Elution with cyclohexane/CH2Cl2 (9:1, v/v) developed three bands. The faster band was unreacted 1 (6 mg), while the second band afforded [Fe2(CO)5(PTh3)(mu-Th)(mu-PTh2)] (2b) (12 mg, 27%) as an orange powder. Spectroscopic data for this band before crystallization showed the presence of a second complex (ca. 10%) that was assigned as [Fe2(CO)5(PTh3)(mu-O=C-Th)(mu-PTh2)] (3b). Recrystallization of the mixture from hexane/CH2Cl2 at 4C gave a crystalline product from which a crystal of [Fe2(CO)5(PTh3)(mu-O=C-Th)(mu-PTh2)] (3b) was selected for crystallography. The third band gave a small amount (ca. 2 mg) of a yellow solid, tentatively identified as [Fe2(CO)6(PTh3)(eta1-Th)(mu-PTh2)]. Spectral data: IR(m(CO), CH2Cl2): 2059 vs, 2018 vs, 1998 s, 1975 w, 1958 br and1895 w. 1H NMR (CDCl3): d 7.88 (d, J 2, 1H), 7.77 (s, 2H), 7.62 (d,J 6, 3H), 7.53 (br, 1H), 7.35 (s, 3H), 7.10 (s, 3H), 6.95 (br, 2H) 6.76(br, 1H), 6.55 (br, 1H), 6.17 (br, 1H). 31P{1H} NMR (CDCl3): d137.0 (d, J 48, P), 40.0 (d, J 48, 1P). Spectral data for 2b: Anal.Calc. for C29H18Fe2O5P2S6: C, 42.87; H, 2.23%. Found: C, 42.91; H,2.25%. IR (m(CO), CH2Cl2): 2038 vs, 1990 s, 1977 sh and 1948 wcm1 1H NMR (CDCl3): d 7.64 (d, J 2.0, 1H), 7.57 (m, 4H), 7.42 (d,J 2.0, 1H), 7.22 (m, 3H), 7.09 (m, 5H), 6.75 (t, J 4.0, 1H) 6.63 (t, J4.0, 1H), 6.37 (m, 1H), 4.79 (d, J 2.0, 1H). 31P{1H} NMR (CDCl3): d92.3 (d, J 24, 1P), 35.0 (d, J 24, 1P). Spectral data for 3b: IR(m(CO), CH2Cl2): 2036 vs, 1981 s, 1952 w and 1934 w cm1.31P{1H} NMR (CDCl3): d 71.7 (d, J 100, 1P), 33.2 (d, J 100, 1P)., 24171-89-9

As the paragraph descriping shows that 24171-89-9 is playing an increasingly important role.

Reference£º
Article; Rahaman, Ahibur; Alam, Fakir Rafiqul; Hossain, Md. Kamal; Abdel-Magied, Ahmed F.; Ghosh, Shishir; Tocher, Derek A.; Haukka, Matti; Kabir, Shariff E.; Nordlander, Ebbe; Hogarth, Graeme; Inorganica Chimica Acta; vol. 430; (2015); p. 208 – 215;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate