Tag: 6372-42-5

6372-42-5, Cyclohexyldiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,6372-42-5

A sample of1 (0.531 g, 1.99 mmol) was dissolved in approximately 8 ml ofTHF. Cyclohexyldiphenylphosphine (1.07 g, 3.98 mmol) wasadded to the solution as a solid, causing effervescence of dinitrogen.The reaction was stirred overnight, at which pointthe volume of THF was reduced to approximately 1-2 ml toprecipitate the product. The colorless residue was filtered offon a fritted filter, rinsed with cold hexanes, and dried for 2 hunder vacuum, leading to isolation of a white powder in 60.8%yield (0.905 g). 1H NMR (CDCl3): 1.13-1.41 (m, 10H), 1.67(d, J = 12.2 Hz, 2H), 1.79 (d, J = 8.7 Hz, 4H), 1.98 (br s, 4H),2.48 (br q, J = 10.9 Hz, 2H), 4.31 (d, J = 16.4 Hz, 4H), 7.41-7.44(m, 13H), 7.56-7.81 (m, 8H), 8.01 (d, J = 7.5 Hz, 2H). 13C{1H}NMR (CDCl3): 26.19, 26.80 (d, J = 13.4 Hz), 37.29 (d, JP-C =77.0 Hz), 49.65, 123.19, 126.66, 126.87, 128.51 (d, J = 10.51 Hz),130.18, 131.01, 131.25, 132.28 (d, J = 7.7 Hz), 143.68 (d, J =18.8 Hz). 31P{1H} NMR (CDCl3): 19.41. Elemental analysiscalculated (%) for C44H49BrN2P2: C 70.68, H 3.75, N 6.61;found: C 70.68, H 3.73, N 6.56.

The synthetic route of 6372-42-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Guillet, Gary L.; Pitts, Skyler L.; Sheriff, Kirkland W.; Rucker, Donna N.; Rogers, Aaryn L.; Acta Crystallographica Section C: Structural Chemistry; vol. 75; (2019); p. 1381 – 1388;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6372-42-5,Cyclohexyldiphenylphosphine,as a common compound, the synthetic route is as follows.,6372-42-5

General procedure: To a solution of 1 (0.2 mmol) in 2 mL of CH3CN/H2O(v/v = 100/1) was added Selectfluor (71 mg, 0.2 mmol). The mixture was stirred at room temperature for 5-60minutes. After removal of the solvent, the residue was then purified by flash column chromatography on silica gel with petroleum ether/ethyl acetate to give the desired product 2.

The synthetic route of 6372-42-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Chen, Qian; Zeng, Jiekun; Yan, Xinxing; Huang, Yulin; Du, Zhiyun; Zhang, Kun; Wen, Chunxiao; Tetrahedron Letters; vol. 57; 30; (2016); p. 3379 – 3381;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6372-42-5,Cyclohexyldiphenylphosphine,as a common compound, the synthetic route is as follows.,6372-42-5

n an air atmosphere containing 200mL to gauge stainless steel autoclave was charged with [Rh (acac) (CO)2] (0.07mmol, 18.1mg) and 0.28mmol of a single phosphine ligands L2 and L12, 0.14mmol bidentate phosphite ligand, and 70mL of anhydrous toluene, connecting the gas line to a synthesis gas (hydrogen: carbon monoxide = 1: 1) after the autoclave was replaced three times the gas, the electromagnetic drive a mechanical stirrer, temperature of the autoclave was heated to 100 deg.] C, passed into the synthesis gas to a total pressure of 2.0MPa, at 100 , 2.0MPa reaction conditions 1h, to obtain a rhodium / (bidentate phosphite – single phosphine ligand) complex catalyst HRh (L12) (L2) (CO)

The synthetic route of 6372-42-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Shanghai Huayi (Group) Company; Lai, Chunbo; Fan, Manman; Yang, Xushi; Li, Yuan; Gao, Shanlin; Huang, Xiaoyun; Liao, Benren; Chen, Jianwei; Gao, Huimin; Zhang, Chunlei; (21 pag.)CN105566081; (2016); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate