Tag: 582.61

Matsuda, Takanori et al. published their research in Organic Letters in 2006 | CAS: 133545-16-1

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Most of these phosphines are acyclic, usually possess low nucleophilic activity, and generally display poor enantioselectivities for phosphine organocatalysis. Name: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)

Enantioselective C-C Bond Cleavage Creating Chiral Quaternary Carbon Centers was written by Matsuda, Takanori;Shigeno, Masanori;Makino, Masaomi;Murakami, Masahiro. And the article was included in Organic Letters in 2006.Name: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) This article mentions the following:

A chiral all-carbon benzylic quaternary carbon center was created by the asym. intramol. addition/ring-opening reaction of a boryl-substituted cyclobutanone, which involved enantioselective β-carbon elimination from a sym. rhodium cyclobutanolate. The asym. reaction was successfully applied to a synthesis of sesquiterpene, (-)-α-herbertenol (I). In the experiment, the researchers used many compounds, for example, (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1Name: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)).

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Most of these phosphines are acyclic, usually possess low nucleophilic activity, and generally display poor enantioselectivities for phosphine organocatalysis. Name: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Shintani, Ryo et al. published their research in Journal of the American Chemical Society in 2006 | CAS: 133545-16-1

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. At present, the synthesis of new chiral phosphines designed specifically for nucleophilic organocatalysis remains a significant challenge. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Application of 133545-16-1

Rhodium-Catalyzed Asymmetric Synthesis of Indanones: Development of a New “Axially Chiral” Bisphosphine Ligand was written by Shintani, Ryo;Yashio, Keiji;Nakamura, Tomoaki;Okamoto, Kazuhiro;Shimada, Toyoshi;Hayashi, Tamio. And the article was included in Journal of the American Chemical Society in 2006.Application of 133545-16-1 This article mentions the following:

A rhodium-catalyzed asym. isomerization of racemic α-arylpropargyl alcs. to β-chiral indanones has been developed. High enantioselectivity has been realized by the use of a newly developed axially chiral bisphosphine ligand. This ligand is unique in the sense that its axial chirality is fixed to a single configuration upon complexation to a transition metal due to other chiral axes existing within the same mol. In the experiment, the researchers used many compounds, for example, (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1Application of 133545-16-1).

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. At present, the synthesis of new chiral phosphines designed specifically for nucleophilic organocatalysis remains a significant challenge. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Application of 133545-16-1

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Hernandez-Toribio, Jorge et al. published their research in Angewandte Chemie, International Edition in 2012 | CAS: 133545-16-1

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Application of 133545-16-1

Catalytic Asymmetric Synthesis of α-Quaternary Proline Derivatives by 1,3-Dipolar Cycloaddition of α-Silylimines was written by Hernandez-Toribio, Jorge;Padilla, Silvia;Adrio, Javier;Carretero, Juan C.. And the article was included in Angewandte Chemie, International Edition in 2012.Application of 133545-16-1 This article mentions the following:

We report an efficient asym. protocol for the CuI-catalyzed 1,3-dipolar cycloaddition of α-silylimines to activated olefins. A variety of α-quaternary proline derivatives were obtained with good yields and excellent levels of diastereoselectivity and enantiocontrol with a variety of dipolarophiles, such as maleimides and α,β-unsaturated sulfones (up to 99% ee). The use of the bulky DTBM-Segphos ligand proved to be crucial for attaining this high enantioselectivity. In the experiment, the researchers used many compounds, for example, (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1Application of 133545-16-1).

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Application of 133545-16-1

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis