Tag: 498.5321

Wang, Duo-Sheng et al. published their research in Tetrahedron Letters in 2010 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Effective chiral catalysts for nucleophilic phosphine catalysis are scarce, seriously limiting the development of asymmetric variants. Application In Synthesis of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Asymmetric hydrogenation of quinolines activated by Bronsted acids was written by Wang, Duo-Sheng;Zhou, Yong-Gui. And the article was included in Tetrahedron Letters in 2010.Application In Synthesis of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) This article mentions the following:

Enantioselective hydrogenation of quinolines and quinoxalines catalyzed by iridium/diphosphine complex with a catalytic amount of Bronsted acid as an activator was developed. In the presence of piperidine·trifluoromethanesulfonic acid as the activator, full conversions and up to 92% ee were obtained. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Application In Synthesis of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Effective chiral catalysts for nucleophilic phosphine catalysis are scarce, seriously limiting the development of asymmetric variants. Application In Synthesis of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Han, Xinxin et al. published their research in Analytical and Bioanalytical Chemistry in 2007 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Generally, the efficiency of nucleophilic phosphine catalysis often depends on the nature of the tertiary phosphine. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Category: chiral-phosphine-ligands

Preparation and evaluation of a new synthetic polymeric chiral stationary phase for HPLC based on the trans-9,10-dihydro-9,10-ethanoanthracene-(11S,12S)-11,12-dicarboxylic acid bis-4-vinylphenylamide monomer was written by Han, Xinxin;Wang, Chunlei;He, Lingfeng;Beesley, Thomas E.;Armstrong, Daniel W.. And the article was included in Analytical and Bioanalytical Chemistry in 2007.Category: chiral-phosphine-ligands This article mentions the following:

A new synthetic polymeric chiral stationary phase for liquid chromatog. was prepared via free-radical-initiated polymerization of trans-9,10-dihydro-9,10-ethanoanthracene-(11S,12S)-11,12-dicarboxylic acid bis-4-vinylphenylamide. The new polymeric chiral stationary phase (CSP) showed enantioselectivity for many chiral compounds in multiple mobile phases. High stability and sample capacities were observed on this polymeric chiral stationary phase. Mobile phase components and additives affected chiral separation greatly. This new synthetic chiral stationary phase is complementary to two other related com. available CSPs: the P-CAP and P-CAP-DP columns. Interactions between the chiral stationary phase and analytes that lead to retention and chiral recognition include hydrogen bonding, dipolar, and π-π interactions. Repulsive (steric) interactions also contribute to chiral recognition. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Category: chiral-phosphine-ligands).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Generally, the efficiency of nucleophilic phosphine catalysis often depends on the nature of the tertiary phosphine. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Category: chiral-phosphine-ligands

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Moeller, Saskia et al. published their research in Journal of Organometallic Chemistry in 2019 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Electric Literature of C31H32O2P2

Investigations into the mechanism of the in situ formation of neutral dinuclear rhodium complexes was written by Moeller, Saskia;Kubis, Christoph;Drexler, Hans-Joachim;Alberico, Elisabetta;Heller, Detlef. And the article was included in Journal of Organometallic Chemistry in 2019.Electric Literature of C31H32O2P2 This article mentions the following:

The often applied in situ formation of neutral dinuclear rhodium precatalysts of the type [Rh(Diphosphine)(μ2-Cl)]2 with the ligands DPEPhos and DIOP has been mechanistically investigated by NMR spectroscopy. The structural characterization of reaction intermediates [Rh2(μ2-Diphosphine)(COD)2(Cl)2] and [Rh2(Diphosphine)(COD)(μ2-Cl)2] was accomplished using x-ray crystallog. So a new and unexpected intermediate was found, which casts a new light on the mechanism of this ligand exchange. In addition, equilibrium could be found which can at least influence the formation of neutral dinuclear rhodium precatalysts. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Electric Literature of C31H32O2P2).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Electric Literature of C31H32O2P2

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Yan, Yuan-Yong et al. published their research in Organic Letters in 2000 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Ligand Tuning in Asymmetric Catalysis: Mono- and Bis-Phospholanes for a Prototypical Pd-Catalyzed Asymmetric Allylation Reaction was written by Yan, Yuan-Yong;RajanBabu, T. V.. And the article was included in Organic Letters in 2000.Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) This article mentions the following:

Enantioselectivities and yields comparable to the best catalysts reported previously can be achieved in the addition of potassium di-Me malonate to diphenylallyl acetate by the use of Pd(0) complexes of bis-phospholanes prepared from D-mannitol. By appropriate changes in the C(2)-C(5) substituents, rare example of a useful monophosphine can also be prepared by a similar route. In both instances, chirality of C(3) and C(5) oxygen seems to play a crucial role in the asym. induction. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Blaser, Hans-Ulrich et al. published their research in Comptes Rendus Chimie in 2002 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Quality Control of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Enantioselective imine hydrogenation with Ir diphosphine catalysts: fighting deactivation was written by Blaser, Hans-Ulrich;Pugin, Benoit;Spindler, Felix;Togni, Antonio. And the article was included in Comptes Rendus Chimie in 2002.Quality Control of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) This article mentions the following:

While Ir diphosphine complexes are very active catalysts for the enantioselective hydrogenation of imines with good to excellent enantioselectivity, their deactivation is often a serious problem, leading to low catalyst productivity. Our study describes attempts to stabilize Ir catalysts with DIOP, BDPP and BPPM ligands for the hydrogenation of different imines. The best results were obtained with complexes immobilized on silica gel and with bimetallic W-Ir and Mo-Ir complexes. In most cases, enantiomeric excesses as well as initial rates were only slightly affected while the stability of the catalysts was enhanced significantly. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Quality Control of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Quality Control of (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Bianchini, Claudio et al. published their research in Advanced Synthesis & Catalysis in 2001 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Although many reactions require more nucleophilic trialkylphosphines as catalysts, only a few chiral trialkylphosphines are available. Indeed, very little research on chiral tertiary phosphine-catalyzed asymmetric reactions occurred prior to the year 2000.SDS of cas: 37002-48-5

Immobilization of optically active rhodium-diphosphine complexes on porous silica via hydrogen bonding was written by Bianchini, Claudio;Barbaro, Pierluigi;Dal Santo, Vladimiro;Gobetto, Roberto;Meli, Andrea;Oberhauser, Werner;Psaro, Rinaldo;Vizza, Francesco. And the article was included in Advanced Synthesis & Catalysis in 2001.SDS of cas: 37002-48-5 This article mentions the following:

The authors describe, for the 1st time, the supported hydrogen-bonded (SHB) immobilization of various optically pure Rh(I) diphosphine complexes, including [((R)-(R)-BDPBzPSO3)Rh(nbd)] (1), which contains the new chiral anionic ligand 4-((R)-Ph2PCHMe)2CHCH2C6H4SO3–, [((+)-DIOP)-Rh(nbd)]OTf (2), and [((S)-BINAP)Rh(nbd)]OTf (3) (nbd = norbornadiene). A preliminary study of the potential of the resulting SHB catalysts in the enantioselective hydrogenation of prochiral olefins is also reported. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5SDS of cas: 37002-48-5).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Although many reactions require more nucleophilic trialkylphosphines as catalysts, only a few chiral trialkylphosphines are available. Indeed, very little research on chiral tertiary phosphine-catalyzed asymmetric reactions occurred prior to the year 2000.SDS of cas: 37002-48-5

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Carmona, Daniel et al. published their research in Chemistry – A European Journal in 2007 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Application of 37002-48-5

Half-sandwich rhodium (and iridium) complexes as enantioselective catalysts for the 1,3-dipolar cycloaddition of 3,4-dihydroisoquinoline n-oxide to methacrylonitrile was written by Carmona, Daniel;Lamata, M. Pilar;Viguri, Fernando;Rodriguez, Ricardo;Lahoz, Fernando J.;Oro, Luis A.. And the article was included in Chemistry – A European Journal in 2007.Application of 37002-48-5 This article mentions the following:

Cationic half-sandwich complexes containing the [(η5-C5Me5)M-(Diphos*)] moiety (M = Rh, Ir; Diphos* = chiral diphosphine ligand) catalyze the cycloaddition of the nitrone 3,4-dihydroisoquinoline N-oxide (A) to methacrylonitrile (B) with excellent regio and endo selectivity and low-to-moderate enantioselectivity. The most active and selective catalyst, (SRh,RC)-[(η5-C5Me5)Rh{(R)-Prophos}(NC(Me)C:CH2)](SbF6)2, has been isolated and fully characterized including the determination of the mol. structure by x-ray diffraction. The R-at-metal epimers of the complexes [(η5-C5Me5)M{(R)-Prophos}(NC(Me)C:CH2)](SbF6)2 (M = Rh, Ir) isomerize to the corresponding S-at-metal diastereomers. The stoichiometric cycloaddition of A with B is catalyzed by diastereopure (SM,RC)-[(η5-C5Me5)M{(R)-Prophos}(NC(Me)C:CH2)](SbF6)2 with perfect regio and endo selectivity and very good (up to 95%) ee. The catalyst can be recycled up to nine times without significant loss of either activity or selectivity. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Application of 37002-48-5).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Application of 37002-48-5

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Li, Yuehui et al. published their research in Journal of the American Chemical Society in 2012 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. At present, the synthesis of new chiral phosphines designed specifically for nucleophilic organocatalysis remains a significant challenge. Over the last decade, however, and especially since 2005, considerable progress has been made in asymmetric phosphine catalysis.Reference of 37002-48-5

Highly Chemoselective Metal-Free Reduction of Phosphine Oxides to Phosphines was written by Li, Yuehui;Lu, Liang-Qiu;Das, Shoubhik;Pisiewicz, Sabine;Junge, Kathrin;Beller, Matthias. And the article was included in Journal of the American Chemical Society in 2012.Reference of 37002-48-5 This article mentions the following:

Unprecedented chemoselective reductions of phosphine oxides to phosphines proceed smoothly in the presence of catalytic amounts of specific Bronsted acids. By utilizing inexpensive silanes, e.g., PMHS or (EtO)2MeSiH, other reducible functional groups such as ketones, aldehydes, olefins, nitriles, and esters are well-tolerated under optimized conditions. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Reference of 37002-48-5).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. At present, the synthesis of new chiral phosphines designed specifically for nucleophilic organocatalysis remains a significant challenge. Over the last decade, however, and especially since 2005, considerable progress has been made in asymmetric phosphine catalysis.Reference of 37002-48-5

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Wu, Xiao-Feng et al. published their research in Chemistry – An Asian Journal in 2010 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.SDS of cas: 37002-48-5

Development of a Second Generation Palladium Catalyst System for the Aminocarbonylation of Aryl Halides with CO and Ammonia was written by Wu, Xiao-Feng;Neumann, Helfried;Beller, Matthias. And the article was included in Chemistry – An Asian Journal in 2010.SDS of cas: 37002-48-5 This article mentions the following:

An improved and general Pd(OAc)2/dppf-catalyzed aminocarbonylation of aryl and heteroaryl bromides and chlorides with CO and ammonia has been established. Primary amides are accessible under comparably mild conditions in good yield. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5SDS of cas: 37002-48-5).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.SDS of cas: 37002-48-5

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Zhang, Yong Jian et al. published their research in Tetrahedron: Asymmetry in 2004 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Phosphine-catalyzed asymmetric reactions are now powerful and versatile tools for the construction of C–C, C–N, C–O, and C–S bonds and for the syntheses of functionalized carbocycles and heterocycles. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Asymmetric synthesis of homoproline derivatives via Rh(I)-catalyzed hydrogenation using chiral bisphosphines as ligands was written by Zhang, Yong Jian;Park, Jung Hwan;Lee, Sang-gi. And the article was included in Tetrahedron: Asymmetry in 2004.Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) This article mentions the following:

It has been demonstrated for the first time that Rh(I)-catalyzed asym. hydrogenation of cyclic β-enamino acid derivatives I [R1 = Me, R2 = Me (1a), OBu-t, OEt; R1 = Et, R2 = Me] using chiral bisphosphines could be a highly efficient synthetic method for optically active homoproline derivatives The enantioselectivity and conversion yield were largely dependent upon the chiral ligand. Using Me-BDPMI which forms a seven-membered metal chelate, the N-acetylated β-enamino acid Me ester 1a was hydrogenated to give optically active homoproline derivative II with 100% conversion and 96% ee. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Phosphine-catalyzed asymmetric reactions are now powerful and versatile tools for the construction of C–C, C–N, C–O, and C–S bonds and for the syntheses of functionalized carbocycles and heterocycles. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Name: (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine)

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis