Category: 932710-63-9

Downstream synthetic route of 932710-63-9

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.932710-63-9,4-(Di-tert-butylphosphino)-N,N-dimethylaniline,as a common compound, the synthetic route is as follows.

932710-63-9, The procedure used to prepare 1a was modified to replace the HgCl2 addition with 0.045 g (0.1 mmol) HgI2. After 1 week, yellow crystals suitable for X-ray analysis were obtained. Yield: 0.052 g,70% based on Hg(SePh)2.Properties: yellow crystalline substance. Melting point: 187-189C. Anal. Calc. for C44H66Hg2I2N2P2Se2 (1497.83): Hg, 26.78;Se, 10.54; C, 35.28; H, 4.44; N, 1.87. Found: Hg, 26.91; Se, 10.62;C, 35.19; H, 4.47; N, 1.84%. IR (KBr): 3051 [vs(CAH)]; 2952[vas(CH3)]; 2872 [vs(CH3)]; 1599, 1472, 1432 [vs(CC)]; 1366[v(CAN)]; 1067, 1022 [dip(CCAH)]; 737, 691 [dop(CCAH)]; 507[v(PAC)]; 466 cm1 [dop(CCAC)] (dip and dop = in-plane and outof-plane bending motions, respectively).

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Stieler, Rafael; Faoro, Eliandro; Cechin, Camila Nunes; Floriano, Luana; Lang, Ernesto Schulz; Journal of Molecular Structure; vol. 1079; (2014); p. 9 – 14;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Analyzing the synthesis route of 932710-63-9

932710-63-9 4-(Di-tert-butylphosphino)-N,N-dimethylaniline 11714598, achiral-phosphine-ligands compound, is more and more widely used in various fields.

932710-63-9, 4-(Di-tert-butylphosphino)-N,N-dimethylaniline is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

932710-63-9, The procedure used to prepare 1a was modified to replace the HgCl2 addition with 0.032 g (0.1 mmol) Hg(SCN)2. After 3 days,white crystals suitable for X-ray analysis were obtained. Yield:0.046 g, 68% based on Hg(SePh)2.Properties: white crystalline substance. Melting point: 195-197 C. Anal. Calc. for C46H66Hg2N4P2S2Se2 (1360.18): Hg, 29.49;Se, 11.61; C, 40.62; H, 4.89; N, 4.12. Found: Hg, 29,40; Se, 11.58;C, 40.81; H, 4.83; N, 4.11%. IR (KBr): 3064 [vs(CAH)]; 2951[vas(CH3)]; 2874 [vs(CH3)]; 2101 [v(SCN)]; 1595, 1472, 1435[vs(CC)]; 1370 [v(CAN)]; 1066, 1021 [dip(CCAH)]; 744, 692[dop(CCAH)]; 507 [v(PAC)]; 465 cm1 [dop(CCAC)] (dip anddop = in-plane and out-of-plane bending motions, respectively).

932710-63-9 4-(Di-tert-butylphosphino)-N,N-dimethylaniline 11714598, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Stieler, Rafael; Faoro, Eliandro; Cechin, Camila Nunes; Floriano, Luana; Lang, Ernesto Schulz; Journal of Molecular Structure; vol. 1079; (2014); p. 9 – 14;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Brief introduction of 932710-63-9

932710-63-9 4-(Di-tert-butylphosphino)-N,N-dimethylaniline 11714598, achiral-phosphine-ligands compound, is more and more widely used in various fields.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.932710-63-9,4-(Di-tert-butylphosphino)-N,N-dimethylaniline,as a common compound, the synthetic route is as follows.

932710-63-9, To a solution of 0.051 g (0.1 mmol) Hg(SePh)2 in 6 mL DMFwere added 0.026 g (0.1 mmol) of PR2R’ (R = tert-butyl; R’ = 4-N,N-dimethylaniline), and the solution was stirred for 1 h. Thesolution was then filtered over Celite, and 6 mL isopropanol waslayered over the mother liqour. After 3 days, yellow crystals suitablefor X-ray analysis were obtained. Yield: 0.047 g, 61% basedon Hg(SePh)2.Properties: yellow crystalline substance. Melting point: 190-192 C. Anal. Calc. for C56H76Hg2N2P2Se4 (1556,14): Hg, 25.78; Se,20.30; C, 43.22; H, 4.92; N, 1.80. Found: Hg, 25.73; Se, 20.26; C,43.15; H, 4.86; N, 1.71%. IR (KBr): 3040 [vs(CAH)]; 2945 [vas(CH3)];2868 [vs(CH3)]; 1596, 1471, 1435 [vs(CC)]; 1361 [v(CAN)]; 1068,1019 [dip(CCAH)]; 735, 694 [dop(CCAH)]; 505 [v(PAC)];460 cm1 [dop(CCAC)] (dip and dop = in-plane and out-of-planebending motions, respectively).

932710-63-9 4-(Di-tert-butylphosphino)-N,N-dimethylaniline 11714598, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Stieler, Rafael; Faoro, Eliandro; Cechin, Camila Nunes; Floriano, Luana; Lang, Ernesto Schulz; Journal of Molecular Structure; vol. 1079; (2014); p. 9 – 14;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Some tips on 932710-63-9

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

932710-63-9, 4-(Di-tert-butylphosphino)-N,N-dimethylaniline is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

932710-63-9, The procedure used to prepare 1a was modified by replacing the HgCl2 addition with 0.036 g (0.1 mmol) HgBr2. After 1 week,yellow crystals suitable for X-ray analysis were obtained. Yield:0.036 g, 51% based on Hg(SePh)2.Properties: yellow crystalline substance. Melting point: 183-185C. Anal. Calc. for C44H66Hg2Br2N2P2Se2 (1403.84): Hg, 28.58;Se, 11.25; C, 37.64; H, 4.74; N, 2.00. Found: Hg, 28.54; Se, 11.21;C, 37.58; H, 4.60; N, 1.93%. IR (KBr): 3043 [vs(CAH)]; 2960[vas(CH3)]; 2867 [vs(CH3)]; 1598, 1476, 1447 [vs(CC)]; 1372[v(CAN)]; 1070, 1024 [dip(CCAH)]; 741, 694 [dop(CCAH)]; 509[v(PAC)]; 468 cm1 [dop(CCAC)] (dip and dop = in-plane and outof-plane bending motions, respectively).

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

Reference£º
Article; Stieler, Rafael; Faoro, Eliandro; Cechin, Camila Nunes; Floriano, Luana; Lang, Ernesto Schulz; Journal of Molecular Structure; vol. 1079; (2014); p. 9 – 14;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Analyzing the synthesis route of 932710-63-9

932710-63-9 4-(Di-tert-butylphosphino)-N,N-dimethylaniline 11714598, achiral-phosphine-ligands compound, is more and more widely used in various fields.

932710-63-9,932710-63-9, 4-(Di-tert-butylphosphino)-N,N-dimethylaniline is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

(r3-1-tBu-indenyl)2(ji-Cl)2Pd2 (3d) (0.300 g, 0.48 mmol) and AmPhos (0.255 g, 0.96 mmol) were added to a 100 mL Schlenk flask and placed under an atmosphere of nitrogen. THF (20 mL) was added to the flask via cannula. The resulting solution was stirred for 60 minutes, during which time the reaction mixture became homogeneous. The mixture was opened to air and 90% of the solvent was evaporated under reduced pressure. Pentanewas added to precipitate solid from solution. A red-orange solid was collected via vacuum filtration. Yield: 0.526 g, 91%.?H NMR (CDC13, 600 MHz): 7.53 (t, 2H), 7.44 (d, 1H), 7.01 (t, 1H), 6.92 (d, 1H), 6.83 (t, 1H), 6.67 (d, 2H), 6.54 (d, 1H), 4.81 (d, 1H), 3.02 (s, 6H), 1.58 (s, 9H), 1.37-1.32 (m, 18H) ppm. ?3C{?H} NMR (CDC13, 150 MHz): 136.85, 136.76, 126.83, 124.44,120.99, 119.18, 110.55, 110.47, 108.43, 108.38, 70.05, 70.02, 40.19, 30.48, 30.44, 30.39,29.69, 29.65 ppm. 31P{?H} NMR (CDC13, 121 MHz): 73.34 ppm. Anal. Calcd for C29H43C1PdPN: C, 60.21; H, 7.49; N, 2.42. Found: C, 59.64; H, 7.51; N, 2.23.

932710-63-9 4-(Di-tert-butylphosphino)-N,N-dimethylaniline 11714598, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; YALE UNIVERSITY; HAZARI, Nilay; MELVIN, Patrick; HRUSZKEWYCZ, Damian; (92 pag.)WO2016/57600; (2016); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Simple exploration of 932710-63-9

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.932710-63-9,4-(Di-tert-butylphosphino)-N,N-dimethylaniline,as a common compound, the synthetic route is as follows.

932710-63-9, Take a dry 10L three-neck reaction flask, dry nitrogen is fully replaced and under nitrogen flow protection,Add 5.5 L of anhydrous tetrahydrofuran, stir and add 540 g of bis(acetonitrile)palladium dichloride.The obtained ligand di-tert-butyl-4-dimethylaminophenylphosphine was further reacted for 30 minutes, and a yellow solid was precipitated. After the reaction was continued for 9 hours at room temperature,After filtration, the filter cake was dipped in anhydrous tetrahydrofuran, drained and dried in a vacuum oven at 60 C.Obtaining a yellow crystalline powdery target product, namely dichlorodi-tert-butyl-(4-dimethylaminophenyl)phosphine palladium, yielding 1440 g to 1445 g,Elemental analysis showed that the product content exceeded 98.0%, the palladium content exceeded 15.0%, and the palladium calculated yield was 97.7% to 98.1%.

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

Reference£º
Patent; Shanxi Ruike New Materials Co., Ltd.; Zhang Wen; Zhao Lei; Hou Yunji; Cai Wanyu; (11 pag.)CN108659054; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

New learning discoveries about 932710-63-9

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

932710-63-9, 4-(Di-tert-butylphosphino)-N,N-dimethylaniline is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 0.051 g (0.1 mmol) Hg(SePh)2 in 6 mL DMF were added 0.027 g (0.1 mmol) HgCl2, and the solution was stirredfor 10 min. Thereafter,0.049 g (0.2 mmol) PR2R’ (R = tert-butyl;R’ = 4-N,N-dimethylaniline) were added, and the mixture was further stirred for 1 h. The solution was then filtered over Celite,and 6 mL isopropanol was layered over the mother liquor. After 1 week, yellow crystals suitable for X-ray analysis were obtained.Yield: 0.034 g, 52% based on Hg(SePh)2.Properties: yellow crystalline substance. Melting point: 148-150C. Anal. Calc. for C44H66Hg2Cl2N2P2Se2 (1314.93): Hg, 30.51;Se, 12.01; C, 40.19; H, 5.06; N, 2.13. Found: Hg, 30.35; Se, 11.86;C, 40.62; H, 5.15; N, 2.08%. IR (KBr): 3053 [vs(CAH)]; 2954[vas(CH3)]; 2898 [vs(CH3)]; 1597, 1473, 1445 [vs(CC)]; 1373[v(CAN)]; 1067, 1020 [dip(CCAH)]; 739, 692 [dop(CCAH)]; 508[v(PAC)]; 465 cm1 [dop(CCAC)] (dip and dop = in-plane and outof-plane bending motions, respectively).

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Stieler, Rafael; Faoro, Eliandro; Cechin, Camila Nunes; Floriano, Luana; Lang, Ernesto Schulz; Journal of Molecular Structure; vol. 1079; (2014); p. 9 – 14;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Downstream synthetic route of 932710-63-9

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.932710-63-9,4-(Di-tert-butylphosphino)-N,N-dimethylaniline,as a common compound, the synthetic route is as follows.

General procedure: [{Pd(mu-Cl)(kappa2N,C-C6H4CH2NMe2)}2] (500 mg, 0.91mmol) and a phosphine (1.82 mmol) were fed into a Schlenk flask under Ar atmosphere.Then, toluene (8 mL) was added to the mixture at room temperature, and the reactionmixture was stirred at 50 C overnight. The solvent was evaporated, and the resultingmass was purified by recrystallization from ether, ethanol, or pentane.

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Rodriguez-Castanon, Jesus; Murayama, Yukako; Sano, Natsuhiro; Sanda, Fumio; Chemistry Letters; vol. 44; 9; (2015); p. 1200 – 1201;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

New learning discoveries about 932710-63-9

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

932710-63-9, 4-(Di-tert-butylphosphino)-N,N-dimethylaniline is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of {Te((2,6-OCH3)2C6H3)}2 (0.053 g, 0.1 mmol) inacetonitrile (5 mL), PdI2 (0.036 g, 0.1 mmol) was added and thesolution was stirred for 2.5 h. In the next step, (4-(N,N-dimethylamino)phenyl)di-tert-butyl phosphine (0.053 g, 0.2 mmol) wasadded and the mixture was stirred for a further 2.5 h. The turbidsolution was filtered through filter paper followed by filtrationthrough Celite. The slow evaporation of solvent afforded air-stabledark red crystals suitable for X-ray analysis. Yield: 0.035 g, 45%based on PdI2. Melting Point: 187-189 C. Analytical data for 2(after drying in vacuum), C52H80I2N4O4P2Pd2Te2 (1608.94 g mol-1):Calcd. C = 38.82%, H = 5.01%, N = 3.48%. Found: C = 40.11%,H = 5.44%, N = 3.52%. FTIR (KBr): 3077 [nus(C-H)Ar.]; 2962[nuas(C-H)Aliph.]; 2891 [nus(C-H)Aliph.]; 1598, 1511, 1464, [nus(C=C)];1245 [nuas(C-O-C)]; 1100 [nus(C-O-C)]; 1017, 945 [deltaip(C=C-H)];812, 764 [deltaop(C=C-H)]; 501 [nu(P-C)].

The synthetic route of 932710-63-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Cechin, Camila N.; Paz, Alisson V.; Piquini, Paulo C.; Bevilacqua, Andressa C.; Pineda, Nahum R.; Fagundes, Natalia V.; Abram, Ulrich; Lang, Ernesto S.; Tirloni, Barbara; Polyhedron; vol. 177; (2020);,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Simple exploration of 932710-63-9

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.932710-63-9,4-(Di-tert-butylphosphino)-N,N-dimethylaniline,as a common compound, the synthetic route is as follows.

To a 500 mL reaction was added 10 g (1,5-cyclooctadiene) palladium dichloride, the reaction flask was replaced with a nitrogen atmosphere,19.6 g of di-tert-butyl-4-dimethylaminophenylphosphine prepared in Example 1 and 200 mL of anhydrous tetrahydrofuran were added, and the mixture was stirred at room temperature for 16 hours,There is a solid precipitation,Filtration and drying gave a pale yellow powder product bis (di-tert-butyl-4-dimethylaminophenylphosphine) palladium chloride 24. 1 g,The yield was 97% (yield based on (1,5-cyclooctadiene) palladium dichloride)The purity of the product was 99.8% by XY-1A intelligent element analyzer.

As the paragraph descriping shows that 932710-63-9 is playing an increasingly important role.

Reference£º
Patent; Panjin Ge Linkaimo Technology Co., Ltd.; Rao Zhihua; Gong Ningrui; (9 pag.)CN105237568; (2017); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate