Category: 63995-70-0

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

Under argon protection,(CH3 (EO) 16N + H = C (N (CH3) 2) 2] [CH3SO3-] and 10 mL of acetonitrile were added to a 50 mLSchlenk flask (SO3Na+)3-R6,4 ¡¤ 73 mmol The reaction mixture was stirred at room temperature for 72 hours. The filtrate was filtered under reduced pressure to give acetonitrile as an orange-yellow viscous liquid in 95% yield.

As the paragraph descriping shows that 63995-70-0 is playing an increasingly important role.

Reference£º
Patent; Qingdao University of Science and Technology; JIN, XIN; LI, SHU MEI; ZHAO, KUN; (11 pag.)CN103483381; (2016); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

Under argon protection,(CH3 (EO) 16N + H = C (N (CH3) 2) 2] [CH3SO3-] and 10 mL of acetonitrile were added to a 50 mLSchlenk flask (SO3Na+)3-R6,4 ¡¤ 73 mmol The reaction mixture was stirred at room temperature for 72 hours. The filtrate was filtered under reduced pressure to give acetonitrile as an orange-yellow viscous liquid in 95% yield.

As the paragraph descriping shows that 63995-70-0 is playing an increasingly important role.

Reference£º
Patent; Qingdao University of Science and Technology; JIN, XIN; LI, SHU MEI; ZHAO, KUN; (11 pag.)CN103483381; (2016); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.63995-70-0,Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate,as a common compound, the synthetic route is as follows.,63995-70-0

General procedure: Palladium complexes were synthetized according to a modified literature procedure [27].Pd(PPh3)4 (103 mg, 0.089 mmol.) was dissolved in 2 g of degassed toluene into a Schlenk tube under nitrogen. The corresponding phosphane (1.5 equiv., 0.133 mmol) was dissolved in 2 g of D2O and cannulated onto the palladium solution. The mixture was stirred for 30 min at room temperature. After decantation, the organic phase was removed and a new degassed Pd(PPh3)4 solution was added to the previous aqueous solution which underwent again a 30 min stirring period to ensure an optimal extraction of the palladium by the hydrosoluble ligand. After decantation, the aqueous phase was recovered. The obtained PdLn (n = 2, 3 or 4) solution was then used for the 31P{1H} NMRstudy. The previous solution usually contained a small excess of free ligand. Study in the presence of RAME-beta-CD was conducted as follow: to 1 mL of the above solution was introduced under nitrogen the required amount of RAME-beta-CD. After 15 min of stirring, the solution was transferred via cannula into a nitrogen pressurized 5 mm NMR tube.

63995-70-0 Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate 6099338, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Ferreira, Michel; Bricout, Herve; Tilloy, Sebastien; Monflier, Eric; Molecules; vol. 22; 1; (2017);,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.63995-70-0,Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate,as a common compound, the synthetic route is as follows.,63995-70-0

Example 1 15.5 g of 2-chloroacetophenone, 31.3 g of 4′-n-pentoxybiphenyl-4-boronic acid, 7.5 g of sodium carbonate and a mixture of 44 mg of palladium as a 22% strength aqueous chloride solution, 1 ml of water and 720 mg of a 0.6M aqueous TPPTS solution together with 120 ml of ethylene glycol and 16 ml of water are placed under nitrogen in a reaction vessel and heated to boiling for 4 hours. After cooling to room temperature, 150 ml of water are added, the mixture is stirred vigorously for another 20 minutes and the solid which remains is filtered off. Crystallization of the residue from acetone and drying at 50 C. under reduced pressure gives 32 g (89%) of 2-(4′-n-pentoxy[1,1′]biphenyl-4-yl)-acetophenone having a melting point of 86 C.

As the paragraph descriping shows that 63995-70-0 is playing an increasingly important role.

Reference£º
Patent; Clariant GmbH; US2001/20104; (2001); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

To a solution of AuCl(tht) (417 mg, 1.30 mM) in 70mL methanol was added TPPTS (738.9 mg, 1.30 mM). After being stirred for approximately 40 min, the solution was filtered through Celite and the filtrate was concentrated under vacuum to about 3mL. Addition of diethyl ether precipitated the colorless complex, which was isolated by filtration, washed with diethyl ether, and dried in vacuum. Yield: 1.00 g (95.7%). 1H NMR (D2O): delta 7.54-7.65 (m), 7.87-7.91 (m). 31P{1H} NMR (D2O): delta 33.73 (s).

63995-70-0 Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate 6099338, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Rezsnyak, Chad E.; Autschbach, Jochen; Atwood, Jim D.; Moncho, Salvador; Journal of Coordination Chemistry; vol. 66; 7; (2013); p. 1153 – 1165;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

Under argon protection,Add in 50 mL Schlenk bottle(SO3Na) 3-R6, 4.73 mmol of [n_C16H33 (EO) 16N + H = C (N (CH3) 2) 2] [CH3SO3-] and 20 mL of acetonitrile,The reaction mixture was stirred at room temperature for 72 hours, filtered and the filtrate was removed under reduced pressure to give an orange yellow viscous liquid in 94% yield.

63995-70-0 Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate 6099338, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Qingdao University of Science and Technology; JIN, XIN; LI, SHU MEI; ZHAO, KUN; (11 pag.)CN103483381; (2016); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.63995-70-0,Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate,as a common compound, the synthetic route is as follows.,63995-70-0

Add 20mg tricine and 5mg TPPTS to the penicillin vial.Add 0.2 mL of physiological saline to dissolve it. Add 25mug SnCl2¡¤2H2O,Then add 10 muL of DMF solution (1 mg/mL) containing ligand HYNICPBB and 0.5 mL of freshly rinsed 99mTcO4-solution.Reaction at 100 C for 30 min,That is, the 99mTc (HYNICPBB) (tricine/TPPTS) complex of the present invention is obtained.

63995-70-0 Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate 6099338, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Beijing Normal University; Zhang Junbo; Song Xiaoqing; Gan Qianqian; Zhang Xuran; Wang Xuebin; Tang Zhigang; Lu Jie; Zhang Zhanbin; (7 pag.)CN110078768; (2019); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

Under argon protection,Add to 50mLSchlenk bottle1 ¡¤ 56 mmol of (SO3Na) 3-R6,4.73 mmol of [CH3 (EO)4N+H=C(N (CH3) 2)2] [CH3SO3-] and 1 mL of acetonitrile,The reaction mixture was stirred at room temperature for 72 hours,Filtration and removal of the filtrate under reduced pressure gave an orange-yellow viscous liquid in 91% yield.

As the paragraph descriping shows that 63995-70-0 is playing an increasingly important role.

Reference£º
Patent; Qingdao University of Science and Technology; JIN, XIN; LI, SHU MEI; ZHAO, KUN; (11 pag.)CN103483381; (2016); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.63995-70-0,Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate,as a common compound, the synthetic route is as follows.,63995-70-0

Under argon protection,Add to 50mLSchlenk bottle1 ¡¤ 56 mmol of (SO3Na+)3-R6, 4¡¤73 mmol of [CH3 (EO)16N+(n-C6H13) = C(N(CH3) 2) 2] [CH3SO3-] and 10 mL of acetonitrile,The reaction mixture was stirred at room temperature for 72 hours,The filtrate was filtered and the acetonitrile was removed under reduced pressure to give an orange-yellow viscous liquid in 95% yield.

As the paragraph descriping shows that 63995-70-0 is playing an increasingly important role.

Reference£º
Patent; Qingdao University of Science and Technology; JIN, XIN; LI, SHU MEI; ZHAO, KUN; (11 pag.)CN103483381; (2016); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

63995-70-0, Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63995-70-0

Example 4 15 g of 2-chlorobenzonitrile, 14.8 g of p-tolueneboronic acid and 28.9 g of sodium carbonate together with 50 ml of p-xylene, 40 ml of DMSO and 10 ml of water are heated to 120 C. At 80 C., a mixture of 24.7 g of palladium acetate and 0.55 ml of 0.6 M aqueous TPPTS solution in 2.5 ml of DMSO is added. After the reaction is complete, the phases are separated. The aqueous phase is washed with 50 ml of xylene. The combined organic phases are washed with 20 ml of water and dried over sodium sulfate. The solvent is evaporated and the residue is crystallized from n-heptane. This gives 18.6 g (88%) of 4′-methylbiphenyl-2-carbonitrile having a melting point of 48-49 C.

63995-70-0 Sodium 3,3′,3”-phosphinetriyltribenzenesulfonate 6099338, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Clariant GmbH; US2001/20104; (2001); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate