Category: 49609-84-9

Category: chiral-phosphine-ligands. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-Chloronicotinoyl chloride, is researched, Molecular C6H3Cl2NO, CAS is 49609-84-9, about Design, synthesis and agricultural evaluation of derivatives of N-Acyl-N-(m-fluoro-benzyl)-6-amino-coumarin. Author is Jin, Yan; Ding, Yin-hao; Dong, Jing-jing; Wei, Yan; Hao, Shuang-hong; Feng, Bai-cheng.

This study aims to design and synthesize a series of N-Acyl-N-(m-fluoro- benzyl)-6- amino-coumarins through the principle of active substructure stitching, which are based on the core structure of N-(m-fluoro-benzyl)-6-amino-coumarin. The structures of target compounds have been characterized by 1H NMR, 13C NMR, ESI-MS and elemental anal. Meanwhile, their agricultural activity have been evaluated in two weeds (Amaranth and Crabgrass) and four widespread noxious pathogens (V. mali, B. cinerea, F. oxysporium and C. bacteria). The herbicidal activity results showed that almost all synthetic mols. have a greater impact on the stem system than on the root. Excellent inhibition rates were discovered from compounds and against Amaranth on stems, which were above 58%(20 mg/L), 68%(100 mg/L) resp. Compounds and also exhibited striking inhibition on stems growth of both weeds. Anti-pathogenic activity showed that all the compounds exerted a better inhibitory activity on B. cinerea at 20 ppm compared to control carbendazim. All the heterocyclic substituted compounds (>57%) made a better influence than the control (54.1%) at the100 ppm. This research provides promising herbicidal and anti-pathogenic agents that have the better effects and can be potential for further development.

If you want to learn more about this compound(2-Chloronicotinoyl chloride)Category: chiral-phosphine-ligands, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(49609-84-9).

Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemical & Pharmaceutical Bulletin called Synthesis and pharmacological evaluation of 3-[(4-oxo-4H-pyrido[3,2-e][1,3]thiazin-2-yl)(phenyl)amino]propanenitrile derivatives as orally active AMPA receptor antagonists, Author is Inami, Hiroshi; Shishikura, Jun-ichi; Yasunaga, Tomoyuki; Hirano, Masaaki; Kimura, Takenori; Yamashita, Hiroshi; Ohno, Kazushige; Sakamoto, Shuichi, which mentions a compound: 49609-84-9, SMILESS is O=C(Cl)C1=CC=CN=C1Cl, Molecular C6H3Cl2NO, Computed Properties of C6H3Cl2NO.

3-[(4-Oxo-4H-pyrido[3,2-e][1,3]thiazin-2-yl)(phenyl)amino]propanenitrile derivatives I [R = 4-Me, 4-F, 4-Br, etc.] were synthesized and administered them to mice to evaluate their anticonvulsant activity in maximal electroshock (MES)- and pentylenetetrazol (PTZ)-induced seizure tests, and their effects on motor coordination in a rotarod test. compounds I [R = 4-trifluoromethoxy, 2,2-difluoro-2H-1,3-benzodioxol-5-yl] exhibited potent anticonvulsant activity in both seizure tests and induced minor motor disturbances as indicated in the rotarod test. The protective index values of I [R = 4-trifluoromethoxy, 2,2-difluoro-2H-1,3-benzodioxol-5-yl] for MES-induced seizures (10.7 and 12.0, resp.) and PTZ-induced seizures (6.0 and 5.6, resp.) were considerably higher compared with those of YM928 and talampanel.

If you want to learn more about this compound(2-Chloronicotinoyl chloride)Computed Properties of C6H3Cl2NO, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(49609-84-9).

Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Chloronicotinoyl chloride( cas:49609-84-9 ) is researched.Electric Literature of C6H3Cl2NO.Takale, Balaram S.; Thakore, Ruchita R.; Mallarapu, Rushil; Gallou, Fabrice; Lipshutz, Bruce H. published the article 《A sustainable 1-pot, 3-step synthesis of boscalid using ppm level Pd catalysis in water》 about this compound( cas:49609-84-9 ) in Organic Process Research & Development. Keywords: boscalid preparation; reduction Suzuki Miyaura cross coupling acylation. Let’s learn more about this compound (cas:49609-84-9).

Herein is disclosed a 1-pot, 3-step route for the synthesis of boscalid using nanomicelles in water as the reaction medium, and a very low loading (700 ppm or 0.07 mol %) of costly and endangered Pd. The developed sequence involves an initial Suzuki-Miyaura cross-coupling, the product from which is not isolated. The second step relies on a carbonyl iron powder (CIP) reduction of the aryl nitro group, followed by the third and final step involving an acylation with the required chloronicotinyl chloride. The overall isolated yield for these three steps is 83%.

Here is a brief introduction to this compound(49609-84-9)Electric Literature of C6H3Cl2NO, if you want to know about other compounds related to this compound(49609-84-9), you can read my other articles.

Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Chloronicotinoyl chloride( cas:49609-84-9 ) is researched.Safety of 2-Chloronicotinoyl chloride.Beesu, Mallesh; Mehta, Goverdhan published the article 《Synthesis of Quinolines and Isoquinolines via Site-Selective, Domino Benzannulation of 2- and 3-Chloropyridyl Ynones with Nitromethane》 about this compound( cas:49609-84-9 ) in Journal of Organic Chemistry. Keywords: quinoline isoquinoline preparation domino benzannulation chloropyridyl ynone nitromethane. Let’s learn more about this compound (cas:49609-84-9).

An approach of general applicability to diverse quinolines and isoquinolines via a tactic that uses the recursive anion from nitromethane as a 1C-connector to stitch easily and appropriately crafted pyridyl ynones through a transition-metal-free, tandem Michael addition-SNAr process is delineated. The straightforwardness, one-pot operation, and good yields mark this methodol. for wider exploitation in targeting more embellished quinolines and isoquinolines and complex platforms embodying these moieties.

Here is a brief introduction to this compound(49609-84-9)Safety of 2-Chloronicotinoyl chloride, if you want to know about other compounds related to this compound(49609-84-9), you can read my other articles.

Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate