Category: 18437-78-0

18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

TFFPP (0.0600 g, 0.189 mmol) was added to a solution of [AuCl(C4H8S)] (0.0146 g, 0.063 mmol) in dichloromethane (20 mL) at -80 ¡ãC and the reaction stirred for 3 h. The solvent was removed by purging nitrogen gas into the solution. The residue was then recrystallized from CH2Cl2/n-hexane mixture for seven days. Partial evaporation of the solvent provided quality crystals. Yield is 98percent. 1H NMR [delta (ppm)]: 7.2(m) and 7.6(m). 31P NMR [delta (ppm)]: 81.1.

18437-78-0, The synthetic route of 18437-78-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Agbeworvi, George; Assefa, Zerihun; Sykora, Richard E.; Taylor, Jared; Crawford, Carlos; Journal of Molecular Structure; vol. 1108; (2016); p. 508 – 515;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Under Argon gas protection, add to the flask with stirrer344 mg of Fe2S2(CO)6 (1 mmol) and 15 mL of tetrahydrofuran solvent,A dark red solution was obtained and the resulting solution was cooled down to -78 ¡ãC in a liquid nitrogen bath.2 mL of lithium triethylborohydride (1M in THF) was added slowly with stirring.After 10 minutes of reaction, 0.18 mL of trifluoroacetic acid was added.After the reaction was continued for 15 minutes, 0.18 mL of formaldehyde solution (37percentwt) was added.The reaction was warmed to room temperature and stirred for 3 h before adding 320 mgP(C6H4-4-F)3 (1.0 mmol), stirring for 10 h at room temperature,The tetrahydrofuran solvent was removed by rotary evaporation and 15 mL of dichloromethane and 0.9 mL of concentrated sulfuric acid were added.Continue to stir the reaction for 18 h, add 15 mL of water, and separateDichloromethane in the organic layer was removed by rotary evaporation and the residue was extracted with dichloromethane.Thin layer chromatography was then performed using a developer having a dichloromethane/petroleum ether volume ratio of 1:3.The main band was collected to obtain the model 2 in a yield of 27percent.

18437-78-0, 18437-78-0 Tris(4-fluorophenyl)phosphine 140387, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Sichuan University of Science and Engineering; Li Yulong; Zou Like; Mu Chao; Deng Chenglong; Wu Yu; Zhao Peihua; Xie Bin; Luo Qiang; (10 pag.)CN106674288; (2017); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The synthesis of the cyclopalladated compounds have been carried out using the procedure described by Onue etal. [16] with minor modifications. In a general procedure, to a stirred suspension of [PdCl(C2,N-aphox)]2 (100mg, 0.18mmol) in 10mL of acetone, 0.38mmol of the suitable phosphine ligand (mass of reactants: L1=99.8, L2=120.3, L3=106.7, L4=105.1, L5=134.0, L6=115.8mg) dissolved in 5mL of acetone was added dropwise, affording a yellow solution. The mixture was stirred for 1hat room temperature and slow evaporation of the final solutions at room temperature afforded crystals in good yields. The crystals were collected, washed with pentane and dried under vacuum. Suitable single crystals for X-ray diffraction determination of 1?5 have been obtained by slow evaporation of a solution containing 2?5mg of the complex in 5mL of acetone. Yellow crystals were obtained after 1 week., 18437-78-0

The synthetic route of 18437-78-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Bozza, Gabriela F.; de Farias, Renan L.; de Souza, Ronan F.F.; Rocha, Fillipe V.; Barra, Carolina V.; Deflon, Victor M.; de Almeida, Eduardo T.; Mauro, Antonio E.; Netto, Adelino V.G.; Journal of Molecular Structure; vol. 1175; (2019); p. 195 – 207;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.

General procedure: PR3 and NH4PF6 were added to a solution of fac-[RuCl3(NO)(P?N)] (1) in MeOH (5 mL) and the resulting orange suspensionwas refluxed for 3 h, except for the P(p-Me-C6H4)3 system whenreaction occurred at r.t. After being cooled to room temperature,the resulting yellow suspensions of complexes 3?5 were filteredto give a yellow solid that was washed with H2O (2 5 mL), MeOH(2 5 mL) and Et2O (2 5 mL), and then dried in vacuo. In the caseof complex 2, the reaction generated a clear yellow solution; thesolvent was removed in vacuo to give a yellow residue that wasthen largely dissolved in CH2Cl2 (5 mL), and the mixture wasfiltered through Celite. Addition of n-hexane (15 mL) yielded a yellowsolid that was then treated as described above. The mer, transisomerof 1 [6,7] could also be used as the precursor for synthesesusing the same methodology, which gave similar product yields., 18437-78-0

The synthetic route of 18437-78-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; da Silva, Juliana P.; Fagundes, Francisco D.; Back, Davi F.; Ellena, Javier; James, Brian R.; de Araujo, Marcio P.; Inorganica Chimica Acta; vol. 454; (2017); p. 40 – 45;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.

General procedure: Complex 1a (24 mg, 0.03 mmol) and appropriate triarylphosphine(0.06 mmol) were suspended in 5ml of acetone, andthe reaction mixture was ultrasonicated for 2 h. The resulting suspensionwas evaporate to dryness and the dry residue was chromatographedon Silica (eluent dichloromethane: methanol = 4: 1)to afford yellow-orange solid of 2a-d.

18437-78-0, As the paragraph descriping shows that 18437-78-0 is playing an increasingly important role.

Reference£º
Article; Zhukovsky, Daniil D.; Sizov, Vladimir V.; Starova, Galina L.; Tunik, Sergey P.; Grachova, Elena V.; Journal of Organometallic Chemistry; vol. 867; (2018); p. 367 – 374;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To 20 mL methanolic suspension of palladium(II) chloride (0.177 g,1 mmol) in a round bottom three-neck flask was added tris(4-fluorophenyl)phosphine (0.316 g, 1 mmol) solution in acetone (20 mL) and sodium 4-(3-methoxyphenyl)piperazine-1-carbodithioate (0.290 g, 1 mmol) solution in methanol (30 mL) in a dropwise manner.The reaction mixture was refluxed for 6 h with constant stirring. The formed greenish precipitate was separated by filtration (scheme 1). This precipitate was re-dissolved in acetone, and on slow evaporation, needle crystals were obtained.Yield: (0.470 g, 60percent), m.p. 250 ¡ãC. Mol. Wt: 745.48: Anal. Calcd C30H27ClF3N2OPPdS2: C, 49.62 (49.65); H, 3.72 (3.68); N, 3.86 (3.80); S, 8.82 (8.79): IR(4000?200 cm?1): 1584 nu(C?N); 1002 nu(CSSsym); 250 nu(Pd?S); 338 nu(Pd?Cl); 218 nu(Pd?P):1H NMR (CDCl3,300 MHz) delta (ppm): 3.81 (s, 3H, H10), 3.89 (t, 4H, H3, H3?, 3J1H,1H = 4.8 Hz), 4.06 (t, 4H, H2, H2?, 3J1H,1H = 5.1 Hz), 6.44 (s, 1H, H5), 6.45 (d, 1H, H9,3J1H,1H = 2.4 Hz), 6.52 (dd, 1H, H8, 3J1H,1H = 2.4, 2.7 Hz), 6.54 (d, 1H, H7, 3J1H,1H = 2.4 Hz), 7.14?7.73 (m, 12H, H12, H12?, H13, H13?). 13C NMR (CDCl3, 75 MHz) delta (ppm): 46.5 (C3, C3?), 48.9 (C2, C2?), 55.3 (C10), 103.6 (C5), 105.9 (C7), 109.6 (C9),116.0 (C12), 125.3 (C13), 130.2 (C8), 151.4 (C4), 160.7 (C6), 163.2 (C11), 165.7 (C14),206.2 (C1). 31P NMR (121.49 MHz, CDCl3) delta (ppm): 24.36.

18437-78-0, As the paragraph descriping shows that 18437-78-0 is playing an increasingly important role.

Reference£º
Article; Khan, Shahan Zeb; Amir, Muhammad Kashif; Naseer, Muhammad Moazzam; Abbasi, Rashda; Mazhar, Kehkashan; Tahir, Muhammad Nawaz; Awan, Iqra Zubair; Zia-Ur-Rehman; Journal of Coordination Chemistry; vol. 68; 14; (2015); p. 2539 – 2551;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.

A solution of (mu3-S)FeCo2(CO)9 (0.069 g, 0.15 mmol) and tris(4-fluorophenyl)phosphane(0.063 g, 0.2 mmol) in CH2Cl2 (10 mL) was added to a solution of Me3NO2H2O (0.022 g,0.2 mmol) and stirred at room temperature for 1 h. The solvent was reduced in vacuo andthe residue was subjected to TLC separation using CH2Cl2:petroleum ether = 1:5 (v/v) aseluent. From the first main brown band, 1 (0.039 g, 35percent) was obtained as a black solid. Fromthe second main brown band, 2 (0.040 g, 26percent) was obtained as a black solid. 1: IR (CH2Cl2,cm?1): nuC?O 2082 (vs), 2039 (vs), 2017 (vs), 1982 (s). 1H NMR (500 MHz, CDCl3): 7.427.38 (m,6H, PhH), 7.14 (t, J = 7.5 Hz, 6H, PhH) ppm. 31P{1H} NMR (200 MHz, CDCl3, 85percent H3PO4): 47.30 (s)ppm. 13C{1H} NMR (125 MHz, CDCl3): 164.22 (d, JP-F = 251.6 Hz, p-PhC), 135.31, 135.21 (dd,JP-C = 12.6 Hz, JP-F = 8.6 Hz, o-PhC), 129.83 (d, JP-C = 44.9 Hz, i-PhC), 116.28, 116.11 (dd,JP-C = 11.4 Hz, JP-F = 21.1 Hz, m-PhC) ppm. Anal. Calcd for C26H12Co2F3FeO8PS: C, 41.85; H, 1.62.Found: C, 41.77; H, 1.98percent. 2: IR (CH2Cl2, cm?1): nuC?O 2047 (s), 2013 (vs), 1984 (s). 1H NMR(500 MHz, CDCl3): 7.42, 7.11 (2s, 24H, PhH) ppm. 31P{1H} NMR (200 MHz, CDCl3, 85percent H3PO4):44.89 (s) ppm. Anal. Calcd for C43H24Co2F6FeO7P2S: C, 49.93; H, 2.34. Found: C, 49.81; H, 2.22percent., 18437-78-0

18437-78-0 Tris(4-fluorophenyl)phosphine 140387, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Zhao, Peng; Liu, Xu-Feng; Wu, Hong-Ke; Journal of Coordination Chemistry; vol. 70; 17; (2017); p. 3080 – 3094;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: 1a (70.5 mg, 0.20 mmol), 4-phenylthioxanthone (3 mg, 0.01 mmol), CH3OH (30 mL) were added to a pyrex reaction flash which was equipped with a magnetic stirrer. The mixture was irradiated by a 23 W household lamp at rt under air atmosphere. The photoreaction was completed after 40 minutes as monitored by TLC (eluent: petroleum ether). The solvent was removed and the residue was purified by flash column chromatography on silica gel (eluent: petroleum ether/ethyl acetate = 10/1?EA) to afford 2a as a solid (74 mg, 100percent); 1H NMR (400 MHz, CDCl3) delta 7.56 (dd, J = 11.6, 8.8 Hz, 6 H), 6.95 (dd, J = 8.8, 2.0 Hz, 6 H), 3.83 (s, 9 H).

18437-78-0, The synthetic route of 18437-78-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ding, Aishun; Li, Shijie; Chen, Yang; Jin, Ruiwen; Ye, Cong; Hu, Jianhua; Guo, Hao; Tetrahedron Letters; vol. 59; 43; (2018); p. 3880 – 3883;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.

To a solution of complex 1 (0.086 g, 0.2 mmol) and P(4-C6H4F)3 (0.063 g, 0.2 mmol) in CH2Cl2 was added asolution of Me3NO*2H2O (0.026 g, 0.23 mmol) in MeCN.The mixture was stirred at room temperature for 1 h, and then the solvent was reduced on a rotary evaporator. The residue was subjected to TLC using petroleum ether aseluent. The main red band afforded 0.101 g (70 percent) ofcomplex 5 as a red solid. IR (KBr disk, cm-1): mC:O 2049(vs), 1983 (vs), 1937 (vs). 1H NMR (500 MHz, CDCl3):7.49?7.45 (m, 6H, PPhH), 7.05 (t, J = 8 Hz, 6H, PPhH),6.53 (d, J = 7.5 Hz, 1H, 6-PhH), 6.22 (s, 1H, 2-PhH), 6.06(d, J = 7.5 Hz, 1H, 6-PhH), 1.86 (s, 3H, CH3) ppm. 31P{1H} NMR (200 MHz, CDCl3, 85percent H3PO4): 60.54(s) ppm. 13C{1H} NMR (125 MHz, CDCl3): 213.50 (d, 2JP-C= 7.2 Hz, PFeCO), 213.22 (d, 2JP-C = 6.7 Hz, PFeCO),208.96 (CO), 163.73 (dd, 4JP-C = 1.4 Hz, 1JF-C =250.9 Hz, p-PPhC), 147.92 (d, JP-C = 2.4 Hz, C6H3C), 143.92(d, JP-C = 2.5 Hz, C6H3C), 135.78, 128.92, 127.00, 125.72(4 s, C6H3C), 135.15 (dd, 2JP-C = 12.9 Hz, 3JF-C = 8.2 Hz, o-PPhC), 131.46 (dd, 1JP-C = 41.5 Hz, 4JF-C = 3.3 Hz, i-PPhC),115.81 (dd, 3JP-C = 10.7 Hz, 2JF-C = 21.2 Hz, m-PPhC),20.28 (CH3) ppm.

18437-78-0, As the paragraph descriping shows that 18437-78-0 is playing an increasingly important role.

Reference£º
Article; Liu, Xu-Feng; Transition Metal Chemistry; vol. 41; 5; (2016); p. 547 – 554;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a solution of complex 1 (0.245 g, 0.5 mmol) in MeCN (15 mL) was added the decarbonylation reagent Me3NO¡¤2H2O (0.056 g, 0.5 mmol). The mixture was stirred at room temperature for 10 min and then PPh3 (0.131 g, 0.5 mmol) was added. The resulting mixture was stirred for additional 2 h to give a dark red solution. Solvents were removed under vacuum and the residue was subjected to TLC using CH2Cl2/petroleum ether (v/v = 1:20) as the eluent. From the main red band, complex 2 (0.152 g, 42percent) was obtained as a dark red solid.

18437-78-0, The synthetic route of 18437-78-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Li, Yu-Long; He, Jiao; Wei, Juan; Wei, Jian; Mu, Chao; Wu, Yu; Xie, Bin; Zou, Li-Ke; Wang, Zheng; Wu, Mei-Li; Li, Han-Min; Gao, Fan; Zhao, Pei-Hua; Polyhedron; vol. 137; (2017); p. 325 – 331;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate