Category: 166330-10-5

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

General procedure: NHC?Cu(I) complexes 1?3 were synthesized by the following route: a solution of imidazolium salt (0.4mmol), copper powder (0.032g, 0.5mmol) and POP (0.22g, 0.4mmol) was reacted in CH3CN (5mL) at 60¡ãC for 24h. The resulting mixture was filtered through a plug of Celite and concentrated to ca. 1mL. The addition of Et2O (10ml) to the filtrate afforded a pale yellow precipitate, which was collected and washed with Et2O. The product was recrystallized with ethanol., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Xu, Shengxian; Wang, Jinglan; Liu, Shaobo; Zhao, Feng; Xia, Hongying; Wang, Yibo; Journal of Molecular Structure; vol. 1153; (2018); p. 12 – 19;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

A mixture of CuI (0.0379g, 0.2mmol), POP (0.1080g, 0.2mmol) and C16H6N6 (0.0565g, 0.2mmol) were dissolved in a mixture of CH2Cl2 (5ml) and CH3OH (5ml), stirred for 6h and filtered. Yellow crystals of 4 were obtained from the filtrate after standing at room temperature for several days. Yield: 85percent. Anal. Calc. for C52H34CuIN6OP2: C, 61.71; H, 3.36; N, 8.31. Found: C, 60.97.11; H, 3.88; N, 7.70percent. IR (cm?1): 3399m, 3050w, 1585w, 1512w, 1461m, 1433m, 1372s, 1259m, 1209s, 1095m, 997w, 873w, 804w, 748s, 697s, 619w, 512s, 425m. 1H NMR (600MHz, CDCl3, 298K) delta, ppm: 7.1?7.4 (m, overlap with the solvent peak signal, C16H6N6-aromatic ring, pop-aromatic ring), 8.6 (d, 2H, C16H6N6-aromatic ring), 8.0 (d, 2H, C16H6N6-aromatic ring)., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Zhang, Yan-Ru; Yu, Xiao; Lin, Sen; Jin, Qiong-Hua; Yang, Yu-Ping; Liu, Min; Li, Zhong-Feng; Zhang, Cun-Lin; Xin, Xiu-Lan; Polyhedron; vol. 138; (2017); p. 46 – 56;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

General procedure: NHC?Cu(I) complexes 1?3 were synthesized by the following route: a solution of imidazolium salt (0.4mmol), copper powder (0.032g, 0.5mmol) and POP (0.22g, 0.4mmol) was reacted in CH3CN (5mL) at 60¡ãC for 24h. The resulting mixture was filtered through a plug of Celite and concentrated to ca. 1mL. The addition of Et2O (10ml) to the filtrate afforded a pale yellow precipitate, which was collected and washed with Et2O. The product was recrystallized with ethanol. [Cu(Ph-BenIm-Py)](PF6), 1. The product was a white powder. Yield: 0.30g, 72percent. 1H NMR (400MHz, DMSO-d6): delta 8.41 (dd, J=20.0, 8.3Hz, 2H), 8.14 (dd, J=15.2, 6.0Hz, 2H), 7.55?7.46 (m, 2H), 7.44?7.31 (m, 8H), 7.27?7.19 (m, 10H), 7.14?6.99 (m, 8H), 6.94 (d, J=7.7Hz, 5H), 6.84 (d, J=7.4Hz, 2H), 6.62 (d, J=3.3Hz, 2H), 5.31 (s, 2H). 13C NMR (101MHz, DMSO-d6). delta 157.54, 150.39, 149.33, 147.58, 141.75, 140.09, 135.23, 134.89, 134.51, 133.67, 132.96, 132.17, 131.58, 131.03, 129.55, 129.15, 128.37, 127.92, 127.57, 126.99, 125.87, 125.23, 124.19, 123.72, 122.98, 121.72, 121.16, 119.69, 114.23, 113.30, 112.59, 111.41, 51.87.31P NMR (162MHz, DMSO-d6): delta?8.95 (s),?143.45 (quint). HRMS (m/z, ESI+): calcd. For C55H43CuN3OP2 ([M]+) 886.2177; found 886.2169. Anal. Calcd. For C55H43CuF6N3OP3 (1032.41): C 63.99, H 4.20, N 4.07; found: C 63.77, H 4.11, N 3.98., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Xu, Shengxian; Wang, Jinglan; Liu, Shaobo; Zhao, Feng; Xia, Hongying; Wang, Yibo; Journal of Molecular Structure; vol. 1153; (2018); p. 12 – 19;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

The resulting precursor P – 3 (4.8 g, 10 mmol, 1.0 equivalent), silver oxide (1.2 g, 5 mmol, 50percent yield), solvent acetonitrile 50 ml are sequentially added into a 100 ml flask, 50 ¡ãC light reaction 12 hours; filter, collecting the filtrate, dryness, a colorless solid. The solid with thecopperpowder (0.64 g, 10 mmol, 1.0 equivalent) as for 100 ml flask, add anhydrous non-oxygen second grade nitrile 50 ml, stirring at the room temperature reaction 5 hours; add ligand POP (4.3 g, 8 mmol, 80percent yield), stirring at the room temperature reaction 3 hours; filter, to remove the insoluble solid, collecting the filtrate, reduced pressure drying, be light green solid, that is the crude product. The crude product is dissolved inmethylenechloridesolvent, slow volatilization of the solvent, a large number of light yellow crystalline precipitation, filtration to obtain pure complex [(NHC – 3) Cu (POP)]+PF6-(8.1 G, 7.5 mmol), yield is 75percent., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Luoyang Normal College; Wang Zhiqiang; Zhang Zhiqiang; Xu Liancai; Sun Xiaojuan; Xu Chen; Li Hongmei; (21 pag.)CN104610285; (2017); B;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: DPEphos (0.1077 g, 0.2 mmol) and dppe (0.0396 g, 0.1 mmol) were dissolved in the mixture of CH2Cl2, CH3OH (10 ml, v/v = 1/1), adding AgOTf (0.0513 g, 0.2 mmol) into the reaction flask. After stirring for 18 h and then filtrating, the filtrate was slow evaporated at ambient temperature. 8 days later, colorless block-shaped crystals were obtained. Yield: 39.2percent (0.0935 g). Anal. Calc. for(C63H52AgF3O4P4S): C, 63.38; H, 4.36; N, 0. Found: C, 63.26; H,4.32; N, 0percent. IR (cm-1, KBr pellets): 3467br, 3055m, 1968w,1660m, 1587m, 1564m, 1482s, 1461s, 1435vs, 1280vs, 1253vs,1223s, 1160s, 1097s, 1069m, 1029vs, 999m, 877w, 798m, 746s,724m, 694vs, 636s, 572w, 512s, 473m, 448w, 421w. 1H NMR(600 MHz, CDCl3): 2.90 (d, 4H, dppe), 6.66?7.28 (m, 48H, Ph). 31P{1H} NMR (243 MHz, CD3Cl): 5.1 (br, d, JAg?P = 364.5 Hz, dppe),5.3 (dt, J19F?P = 211.4 Hz, dppe), 10.1 (2d, J19F?P = 102.1 Hz, DPEphos),11.3 (2d, J19F?P = 116.7 Hz, DPEphos), 11.5 (dd, J109Ag?P = 245.4 Hz,J107Ag?P = 235.7 Hz, DPEphos)., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Gao, Sen; Li, Zhong-Feng; Liu, Min; Jin, Qiong-Hua; Chen, Yu; Deng, Zi-Jun; Zhang, Zhen-Wei; Zhang, Cun-Li; Polyhedron; vol. 83; (2014); p. 10 – 15;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: NHC-Cu(I) complexes 1-3 were synthesized by the following route:a solution of imidazolium salt (0.4 mmol), copper powder (0.032 g,0.5 mmol) and POP (0.22 g, 0.4 mmol) reacted in CH3CN (5 mL) at60 C for 24 h. The resulting mixture was filtered through a plug ofCelite and concentrated to ca. 1 mL. Addition of Et2O (10 ml) to thefiltrate afforded a pale yellow precipitate, which was collected andwashed with Et2O. And the productwas recrystallized with ethanol., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Wang, Jinglan; Liu, Shaobo; Xu, Shengxian; Zhao, Feng; Xia, Hongying; Wang, Yibo; Journal of Organometallic Chemistry; vol. 846; (2017); p. 351 – 359;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

[Cu(CH3CN)4]ClO4 (16.3 mg, 0.050 mmol) was added to a mixtureof ppipH (19.3 mg, 0.050 mmol) and POP (27.9 mg, 98%,0.050 mmol) in DCM under a stream of dry argon with a vacuum-line system and Schlenk techniques and the mixture was stirredfor 2 h at room temperature. After filtration, layering n-hexanecarefully onto the DCM filtrate produced orange-yellow crystals afew days later as 1aCH2Cl2. The orange-yellow product wasobtained in a 55.4% yield (32.4 mg) after being dried under aninfrared lamp. Mp: 200.9-201.7 C. 1H NMR (400 MHz, DMSO-d6,d, ppm): 14.67 (s, 1H, NH), 9.07 (d, J = 8.0 Hz, 2H), 8.87 (d,J = 4.4 Hz, 2H), 7.93 (s, br, 2H), 7.45 (td, J = 7.6 Hz, J0 = 1.2 Hz, 2H),7.32-7.18 (m, 14H), 7.10 (t, J = 7.6 Hz, 2H), 7.00-6.96 (m, 8H),6.65-6.62 (m, 2H). 31P NMR (400 MHz, DMSO-d6, d, ppm):11.22. Characteristic IR spectrum (KBr, cm1): 3144 s (NH),1097 s (ClO4). ESI-MS (m/z): 987.1493 [Cu(ppipH)(POP)]+ (Calc.987.1497)., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Liu, Xia; Shan, Yuyu; Xu, Jie; Zhang, Xia; Shang, Sitong; Li, Xiu-Ling; Polyhedron; vol. 164; (2019); p. 152 – 158;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

166330-10-5, (Oxybis(2,1-phenylene))bis(diphenylphosphine) is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: PyIm-Cu(I) complexes P1?P4 were synthesized by the following route: [Cu(CH3CN)4](PF6) (0.124g, 0.4mmol) and POP (0.216g, 0.4mmol) reacted in dichloromethane (15ml) at 25¡ãC for 2h. Then, the corresponding PyIm ligand (0.4mmol) was dissolved in the degassed dichloromethane solution and injected into the mixed solution for 2h. The resulting mixture was filtered through a plug of Celite and concentrated to ca. 1ml. Addition of Et2O (10ml) to the filtrate afforded a pale yellow precipitate, which was collected and washed with Et2O. And the product was recrystallized with ethanol., 166330-10-5

As the paragraph descriping shows that 166330-10-5 is playing an increasingly important role.

Reference£º
Article; Wang, Jinglan; Chai, Chaoyang; Xu, Shengxian; Zhao, Feng; Xia, Hongying; Wang, Yibo; Inorganica Chimica Acta; vol. 484; (2019); p. 237 – 244;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

Copper(I) hexafluorophosphate (2.4 mg, 0.0064 mmol) and bis[2-(diphenylphosphino)phenyl]ether (3.4 mg, 0.0064 mmol) were stirred in dehydrated methylene chloride (2 mL) under an argon atmosphere at room temperature for 2 hours. A solution (1 mL) of the compound B4 (10.8 mg, 0.0064 mmol) in dehydrated methylene chloride was added to the reaction solution, the homogeneous reaction solution was stirred at room temperature for 1 hour, and the reaction solution was concentrated and dried to obtain the metal complex C5.1H NMR (300 MHz, CDCl3): delta 9.00 (s, 2H), 8.79 (s, 2H), 8.28 (s, 2H), 8.11 (s, 2H), 7.91 (s, 4H), 7.86 (s, 8H), 7.70 (d, J=7.2 Hz, 16H), 7.52 (d, J=7.2Hz, 16H), 6.95 (br, 20H), 6.89-6.80 (m, 4H), 6.74 (br, 2H), 6.69 (br, 2H), 1.38 (s, 36H).31P NMR (122 MHz, CDCl3): delta-8.82.The metal complex C5 emitted yellow light under ultraviolet excitation (365 nm), the emission peak wavelength was 572.5 nm, and the excitation lifetime was 1.4 mus.The metal complex C5 was easily dissolved in chloroform, toluene, and xylene at room temperature.When the metal complex C5 was left to stand in air at 100¡ã C. for 7 hours, change in emission intensity was hardly observed., 166330-10-5

The synthetic route of 166330-10-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; US2012/41203; (2012); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.166330-10-5,(Oxybis(2,1-phenylene))bis(diphenylphosphine),as a common compound, the synthetic route is as follows.

The terminating ligand dpepo was obtained by oxidizing the precursor DPEphos (diepiii phosph) with hydrogen peroxide., 166330-10-5

166330-10-5 (Oxybis(2,1-phenylene))bis(diphenylphosphine) 4285986, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; HOKKAIDO UNIVERSITY; STANLEY ELECTRIC COMPANY LIMITED; OSAKA PREFECTURE UNIVERSITY; HASEGAWA, YASUCHIKA; NATORI, SHIORI; NAKANISHI, TAKAYUKI; KITAGAWA, YUICHI; FUSHIMI, KOJI; AKAGI, TSUTOMU; NAITO, HIROYOSHI; FUKUDOME, JUN; (32 pag.)JP2018/35101; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate