Category: 13991-08-7

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1,2-Bis(diphenylphosphino)benzene (DPPBz) ligand (0.405g, 0.907mmol) was dissolved in a minimal amount of THF (no more than 7mL) in a glovebox at room temperature with stirring in a 25mL round bottom flask fitted with a rubber septum. Then 0.2mL (0.0907mmol) of Fe(CO)2(NO)2/THF solution (1:1 ratio) was introduced into the flask via syringe. The solution was allowed to stir at room temperature overnight to produce the monosubstituted product, Fe(NO)2(CO)(DPPBz). After stirring, the reaction mixture was taken out of the glovebox and gently heated at 50C for 24h with the reaction progress monitored through FT-IR spectroscopy. The solution was transferred back into the glovebox after completion of the double substitution. Large dark purple crystals of X-ray quality ranging in size from 0.5 to 3mm3were grown by allowing the solvent to slowly evaporate over several days through a vent needle. The crystals and solid powder from the bottom of the flask were filtered and washed with three 0.5mL aliquots of cool toluene.

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Holloway, Lauren R.; Clough, Andrew J.; Li, Jessica Y.; Tao, Emily L.; Tao, Fu-Ming; Li, Lijuan; Polyhedron; vol. 70; (2014); p. 29 – 38;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A benzene solution (20mL) of 1 (50mg, 0.074mmol) and dppb (33mg, 0.074mmol) was refluxed for 5h. The solvent was removed under reduced pressure and the residue was chromatographed by TLC on silica gel. Elution with n-hexane/CH2Cl2 (7:3 v/v) developed two bands in addition to intractable, presumably decomposed, material. The faster moving band gave [ Fe4(CO)10 (mu3-Te)4 (kappa2-dppb)] (8) (13mg, 12%) as black crystals and the second band afforded [Fe3(CO)8(mu3-Te)2(kappa2-dppb)] (4) (20mg, 25%) as red crystals after recrystallization from hexane/CH2Cl2 at 4C. Characterization data for 4: IR (nu(CO), CH2Cl2): 2042s, 2021s, 1998vs, 1964s cm-1. 1H NMR (CDCl3): delta 7.70-7.67 (m, 4H), 7.59-7.34 (m, 10H), 7.24-7.03 (m, 10H). 31P{1H} NMR (CDCl3): delta 74.2 (s). ESI-MS: m/z 1093.24 (M+, calc. 1093.27). Characterization data for 8: IR (nu(CO), CH2Cl2): 2053s, 2029vs, 1977s, 1908w cm-1. 1H NMR (CDCl3): delta 7.67-7.04 (m, 24H). 31P{1H} NMR (CDCl3): delta 53.5 (s). ESI-MS: m/z 1460.33 (M+, calc.1460.34).

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Rahaman, Ahibur; Lisensky, George C.; Tocher, Derek A.; Richmond, Michael G.; Hogarth, Graeme; Nordlander, Ebbe; Journal of Organometallic Chemistry; vol. 867; (2018); p. 381 – 390;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Several ml of toluene were condensed into evacuated ampoule containing the mixture of 5mg (1 eq) of (CO)2Rh(SQ) and 1.1 eq of corresponding diphos under intensive cooling by liquid N2. Solution was quickly brought to room temperature with shaking and placed into EPR cavity immediately. All of reactions were carried out without isolation of the products.

13991-08-7, As the paragraph descriping shows that 13991-08-7 is playing an increasingly important role.

Reference£º
Article; Kozhanov; Bubnov; Teplova; Abakumov; Cherkasov; Journal of Molecular Structure; vol. 1147; (2017); p. 541 – 548;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

Example 7 (EX 7) (0136) IrCl3(THT)3 (150 mg, 0.27 mmol) was placed in a round-bottom flask, (0137) (119 mg, 0.27 mmol), 15 ml decalin, and 15 ml dimethylformamide were subsequently added thereto to obtain the first mixture. The first mixture was heated under reflux and under a nitrogen atmosphere for a period of 6 hours. After the reaction was completed and the temperature was cooled down to room temperature, decalin in the first mixture was removed by reduced pressure distillation. Thereafter, (0138) (51 mg, 0.27 mmol) and 15 ml dimethylformamide were sequentially added to the first mixture, from which decalin was removed, to obtain a second mixture. The second mixture was heated under reflux and under a nitrogen atmosphere for a second reaction period of 12 hours. After the reaction was completed and the temperature was reduced to room temperature, dimethylformamide in the second mixture was removed by reduced pressure distillation to obtain a solid. The solid was washed using diethyl ether to obtain an intermediate product (400 mg, 70% yield).

13991-08-7, The synthetic route of 13991-08-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; National Tsing Hua University; Chi, Yun; Liao, Jia-Ling; US8957208; (2015); B1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

32.6mg mesityl -Cu and 3ml of toluene were added to 34.6mg (0.18mmol) of 8-PyQ and 79.5mg (0.18 mmol) of dppb in a glove box. It forms a dark Redsolution. This was filtered and coated with n-hexane layer. it forms redcrystals. under UV (356nm), they emit a strong red. the solution in the sameway emits a strong red. Yield: 70%.

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; MERCK PATENTGMBH; WESEMANN, LARS; KLEIH, MATTHIAS; MAYER, HERMANN, AUGUST; (72 pag.)JP2016/501830; (2016); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

Under argon atmosphere, 1,2-bis(diphenylphosphino)benzene (91.7 mg, 0.205 mmol) was added to 5 mL of the suspension of silver(I) tetrafluoroborate (40.0 mg, 0.205 mmol) in dry dichloromethane, and the mixture was stirred at room temperature for one hour. Then, 2,2′-biquinoline (52.7 mg, 0.205 mmol) was added to the reaction solution, which was stirred at room temperature for another one hour. The pale yellow reaction solution was filtrated, and the filtrate was concentrated, subjected to recrystallization by slow diffusion of chloroform-ether, and dried to provide 171 mg of the pale yellow solid complex. The result of elemental analysis for the obtained complex is shown in Table 2-2, and the composition ratio of the complex was obtained. The present complex corresponds to the above composition formula (5).

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various.

Reference£º
Patent; Sumitomo Chemical Company, Limited; EP2360162; (2011); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate