Category: 13991-08-7

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Under argon atmosphere, 20 mL of dry acetonitrile was added to silver(I) bromide (170 mg , 0.904 mmol) and 1,2-bis(diphenylphosphino)benzene (404 mg, 0.904 mmol), and the mixture was stirred at room temperature for one hour and then heated to reflux for seven hours. The reaction solution was allowed to reach room temperature, concentrated, and filtrated after being suspended in 9 mL of chloroform. The filtrated matter was subjected to thermal recrystallization from acetonitrile-chloroform and dried to obtain 399 mg of the colorless crystal complex. Under argon atmosphere, 3 mL of dry dichloromethane was added to the above obtained complex (80.0 mg, 0.0631 mmol) and triphenylphosphine (33.1 mg, 0.126 mmol), and the mixture was stirred at 40C for 10 minutes. The reaction solution was concentrated, subjected to recrystallization by slow diffusion of chloroform-ether, and dried to provide 108 mg of the complex. The result of elemental analysis for the obtained complex is shown in Table 2-2, and the composition ratio of the complex was obtained. The present complex corresponds to the above composition formula (3). The NMR data of the obtained complex is provided below. 1H NMR (300 MHz, CDCl3) delta 7.48-7.17 (m, 31H), 7.07-7.03 (m, 8H); 13C NMR (75 MHz, CDCl3) delta 134.8 (t, J = 2.4 Hz), 134.6-134.2 (m), 130.2-130.0 (m), 129.7 (br), 129.0 (br), 128.9 (br), 128.7-128.6 (m); 31P NMR (122 MHz, CDCl3) delta 8.1 (br, W1/2 = 87 Hz) , -14.8 (br, W1/2 = 340 Hz). The result of DART-MS measurement for the obtained complex is provided below. DART-MS (M/Z): found; 815.16. calcd; 815.13 (M-Br)+. Based on the DART-MS measurement of the obtained complex, it was confirmed that the obtained complex contained the following structure.

13991-08-7, The synthetic route of 13991-08-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Sumitomo Chemical Company, Limited; EP2360162; (2011); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

10119] In a schlenk flask provided with a teflon closure, a solution of Os(tetradentate ligand)(DMSO)2 (200 mg, 0.2 64 mmol) in THF (10 mL) was treated with 1,2-bis(diphe- nylphosphino)benzene (118 mg, 0.264 mmol). The resulting mixture was stirred at 100 C. for 60 hours to produce a yellow solution. Afier cooling at room temperature (.-22 C.), the solvent was removed in vacuo. After extraction with dichioromethane, the solid was filtered off and the solution was evaporated to dryness. Addition of 5 mL of acetonitrile caused precipitation of a yellow solid that was washed with thrther portions of acetonitrile (2×5 mL) and subsequently with diethyl ether (3×5 mL). The yellow solid was dried in vacuo. Yield: 215mg (68%). IR (cm?): v(C=C) 1570 (w). ?H NMR (500 MHz, CD2C12, 298 K): oe 8.00 (dd, JHH=7.0,JHH=1.5, 1H, CH), 7.63 (t, JHH=8.0, 2H, CH), 7.58 (m, 1H,CH), 7.53-7.50 (m, 3H, CH), 7.38 (d, 1H, CH), 7.35(d, H-H=, 1H, CH), 7.29-7.25 (m, 8H, CH), 7.16-7.14 (m,3H, CH), 7.08-7.00 (m, 3H, CH), 6.95-6.88 (m, 6H, CH),6.79-6.76 (m, 3H, CH), 6.73 (t, H-H=, 1H, CH), 6.63 (dt,JHH=1.0, JHH=7.2, 1H, CH), 6.59 (dt, JHH=1.0, JHH=7.0,1H, CH), 6.39-6.35 (m, 3H, CH), 6.30 (t, 6.30 (t, JHH=8.5,2H, CH), 5.80-5.74 (m, 1H, -CH2—-), 4.32-4.28 (m, 2H,-CH2-), 3.86-3.80 (m, 1H, -CH2-). ?3C{?H} NMR(125.68 MHz, CD2C12, 298 K): oe 210.9 (t, J=4.3, NCN),187.4 (dd, J,=7.9, J,=79.7, NCN), 158.1 (t, J=6.4,Os-C Ph), 153.9 (dd, J=12.5, J=55.5, Os-C Ph),151.7 (d J=3.2, Cq), 149.4 (d, J=3.8, Cq), 148.6 (dd,J=47.2, J=34.2, Cq), 144.9 (dd, J=41.9, J=36.3,Cq), 143.7 (d, J=5.4, Cq), 143.5 (d, J=5.4, CH), 142.3(s, CH), 138.3 (d, J=3.6, Cq), 137.2 (d, J=28.8, Cq),137.0, 136.7 (both s, Cq), 136.2 (d, J=9.7, CH), 133.8 (d,J=11.9, CH), 133.5 (dJ=3.3, Cq), 132.8 (d, J=14.8,CH), 132.3 (d, J,=1 .9, Cq), 132.2 (d, J=10.3, CH), 131.9(dd, J=6.9, J=31.8, Cq), 131.7 (d, J=13.9, CH),130.0 (d, j=9.3, CH), 129.6 (d, j=3.9, CH), 129.2,129.0 (both s, CH), 128.9 (d, J=3.6, CH), 128.3 (s, CH),127.9 (d, J=9.0, CH), 127.5, 127.4 (both s, CH), 127.2 (d,J=8.7, CH), 126.4 (d, J=8.4, CH), 123.3, 122.7, 122.5,122.0, 121.7,121.1, 120.4,119.3, 112.3,111.2, 111.1, 110.6,109.7, 107.3 (all s, CH), 47.5 (s, -CH2-), 45.0 (d, J=3.5,-CH2—-). 3?P{?H} NMR (121.4 MHz, CD2C12, 298 K): oe32.1 (d, j=s?s), 18.7 (d, J=5.5).

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Universal Display Corporation; TSAI, Jui-Yi; XIA, Chuanjun; ESTERUELAS, Miguel A.; ALABAU, Roberto G.; OLIVAN, Montserrat; ONATE, Enrique; (89 pag.)US2016/240799; (2016); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

A toluene solution (20mL) of 1 (22mg, 0.043mmol) and dppb (18mg, 0.043mmol) was refluxed under a nitrogen atmosphere for 27 h. The solvent was removed under reduced pressure and the residue was chromatographed by TLC on silica gel. Elution with cyclohexane/CH2Cl2 (4:1 v/v) developed two bands. The faster band was unreacted 1 (2mg) while the slower moving band afforded [Fe2(CO)5{mu,kappa2-C6H4PPh(C6H4)PPh2}(mu-PFu2)] (7) (20mg, 66%) as red crystals after recrystallization from hexane/CH2Cl2 at 4C. Spectral data for 7: Anal. Calcd for C39H29Fe2O7P3: C, 57.52; H, 3.60. Found: C, 57.62; H, 3.88%. IR (nu(CO), CH2Cl2): 2023 s, 1983 vs, 1945 w cm-1. 1H NMR (CDCl3): delta 5.72-5.63 (m, 1H, Fu), 6.08 (m, 1H, Fu), 6.20 (m, 1H, Fu), 6.29 (m, 2H, Fu), 6.31 (m, 1H, Fu), 6.53-6.41 (m, 2H, Ph), 6.83-6.80 (m, 3H, Ph), 7.18-7.10 (m, 5H, Ph), 7.48-7.30 (m, 9H, Ph), 7.96-7.62 (m, 4H, Ph). 31P{1H} NMR (CDCl3): delta 138.7 (dd, J=54, 30Hz), 90.5 (t, J=55Hz), 82.7 (dd, J=50, 30Hz)., 13991-08-7

As the paragraph descriping shows that 13991-08-7 is playing an increasingly important role.

Reference£º
Article; Rahaman, Ahibur; Alam, Fakir Rafiqul; Ghosh, Shishir; Tocher, Derek A.; Haukka, Matti; Kabir, Shariff E.; Nordlander, Ebbe; Hogarth, Graeme; Journal of Organometallic Chemistry; vol. 751; (2014); p. 326 – 335;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

Under argon atmosphere, silver(I) iodide (235 mg, 1.00 mmol) and 50 mL of the solution of 1,2-bis(diphenylphosphino)benzene (447 mg, 1.00 mmol) in acetonitrile were mixed and the mixture was heated to reflux with stirring for seven hours. The reaction solution was allowed to reach room temperature and the precipitated colorless crystal was filtrated. The obtained filtrated matter was washed with acetonitrile and dried to obtain 531 mg of the complex. The mixture of this complex (49.7 mg) and triphenylphosphine (19.2 mg, 0.0730 mmol) was dissolved in 3 mL of dichloromethane, and the resulting solution was stirred for 30 minutes at room temperature. The reaction solution was concentrated, subjected to recrystallization by slow diffusion of chloroform-diethylether, and dried to provide 30.9 mg of the colorless solid complex. The result of elemental analysis for the obtained complex is shown in Table 2-1, and the composition ratio of the complex was obtained. The present complex corresponds to the above composition formula (3). [Show Image] The NMR data of the obtained complex is provided below. 1H NMR (300 MHz, CDCl3) delta 7.44-7.14 (m, 31H), 7.03 (t, J= 7.2 Hz, 8H); 13C NMR (75 MHz, CDCl3) delta 141.2 (t, J= 22.7 Hz), 134.5 (t, J= 3.0 Hz), 134.2-134.0 (m), 133.3 (d, J= 22.2 Hz), 132.2 (t, J= 10.9 Hz), 129.6 (s), 129.3 (s), 128.5 (d, J= 9.0 Hz), 128.2 (t, J= 4.5 Hz); 31P NMR (122 MHz, CDCl3) delta 3.7 (br, W1/2=159 Hz), -14.8 (br, W1/2 = 450 Hz). The result of DART-MS measurement of the obtained complex is provided below. DART-MS (M/Z): found; 815.16. calcd; 815.13 (M-I)+. Based on the DART-MS measurement of the obtained complex, it was confirmed that the obtained complex contained the following structure.

13991-08-7, As the paragraph descriping shows that 13991-08-7 is playing an increasingly important role.

Reference£º
Patent; Sumitomo Chemical Company, Limited; EP2360162; (2011); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Under argon atmosphere, 25 mL of dry acetonitrile was added to silver(I) chloride (150 mg, 1.04 mmol) and 1,2-bis(diphenylphosphino)benzene (467 mg, 1.04 mmol), and the mixture was stirred at room temperature for one hour, followed by reflux for five hours. The reaction solution was allowed to reach room temperature, concentrated, and filtrated after being suspended in 7 mL of chloroform. The filtrated matter was subjected to thermal recrystallization from acetonitrile-chloroform and dried to obtain 258 mg of the colorless crystal complex. Under argon atmosphere, 3 mL of dry dichloromethane was added to the above obtained complex (80.0 mg, 0.0678 mmol) and triphenylphosphine (35.6 mg, 0.136 mmol), and the mixture was stirred at 40C for 10 minutes. The reaction solution was concentrated, subjected to recrystallization by slow diffusion of chloroform-ether, and dried to provide 107 mg of the colorless crystal complex. The result of elemental analysis for the obtained complex is shown in Table 2-2, and the composition ratio of the complex was obtained. The present complex corresponds to the above composition formula (3). [Show Image] The NMR data of the obtained complex is provided below. 1H NMR (300 MHz, CDCl3) delta 7.48-7.17 (m, 31H), 7.06 (t, J = 7.0 Hz, 8H); 13C NMR (75 MHz, CDCl3) delta 134.9-134.8 (m), 134.5 (br), 134.4-134.1 (m), 130.1 (br), 129.7 (br), 129.8-129.7 (m), 129.0 (br), 128.9 (br), 128.8-128.7 (m); 31P NMR (122 MHz, CDCl3) delta 9.1 (br, W1/2 = 66 Hz), -14.8 (br, W1/2 = 390 Hz). The result of DART-MS measurement for the obtained complex is provided below. DART-MS (M/Z): found; 815.16. calcd; 815.13 (M-C1)+. Based on the DART-MS measurement of the obtained complex, it was confirmed that the obtained complex contained the following structure.

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Sumitomo Chemical Company, Limited; EP2360162; (2011); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

General procedure: A mixture of CuCl (19.6mg, 0.2mmol) and dppb (89.3mg, 0.2mmol) with an excess of batho (66.5mg, 0.2mmol) were dissolved in CH2Cl2 (5mL) and 17 CH3OH (5mL) solution, stirred at room temperature for 6h. The insoluble residues were removed by filtration, and the filtrate was evaporated slowly at room temperature to yield yellow crystalline products., 13991-08-7

13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Yu, Xiao; Fan, Weiwei; Wang, Guo; Lin, Sen; Li, Zhongfeng; Liu, Min; Yang, Yuping; Xin, Xiulan; Jin, Qionghua; Polyhedron; vol. 157; (2019); p. 301 – 309;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

The experimental multi-tooth phosphine coordination silver complex double emitting dye synthesis method according to the following steps:1 mmol of multidentate phosphine ligand, 1 mmol of AgBr, 5 ml of DCM were mixed and reacted at 40 C. for 10 hours. The mixture was spin-dried and purified by column chromatography with DCM and PE to obtain a multidentate phosphine coordination silver complex.Wherein the ratio of multidentate phosphine ligand to AgBr is 1: 1.The volume ratio of DCM to PE in the mixed solvent of DCM and PE is 1:20.

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Heilongjiang University; Xu Hui; Zhang Jing; Han Chunmiao; (47 pag.)CN106833010; (2017); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Example 6 (EX 6) (0129) IrCl3(THT)3 (300 mg, 0.63 mmol) was placed in a round-bottom flask, (0130) (239 mg, 0.63 mmol) and 20 ml decalin were subsequently added thereto to obtain the first mixture. The first mixture was heated under reflux and under a nitrogen atmosphere for a period of 6 hours. After the reaction was completed and the temperature was reduced to room temperature, decalin in the first mixture was removed by reduced pressure distillation. Thereafter, (0131) (122 mg, 0.63 mmol) and 15 ml dimethylformamide were sequentially added to the first mixture, from which decalin was removed, to obtain a second mixture. The second mixture was heated under reflux and under a nitrogen atmosphere for a second reaction period of 12 hours. After the reaction was completed and the temperature was cooled down to room temperature, dimethylformamide in the second mixture was removed by reduced pressure distillation to obtain a solid. The solid was washed using diethyl ether to obtain an intermediate product (400 mg, 80% yield)., 13991-08-7

As the paragraph descriping shows that 13991-08-7 is playing an increasingly important role.

Reference£º
Patent; National Tsing Hua University; Chi, Yun; Liao, Jia-Ling; US8957208; (2015); B1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13991-08-7,1,2-Bis(diphenylphosphino)benzene,as a common compound, the synthetic route is as follows.

Similar proceduredescribed for 2a was used in the synthesis of 5a using dppbz instead of dppe to obtain a pale yellow solid. Yield:70%. 31P-NMR (121.42 MHz, 298 K, CDCl3): 62.3 ppm(d, 1J(Rh-P) = 134 Hz). 1H-NMR (300 MHz, 298 K,CDCl3): 7.59-6.83 (m, Ph ? P – C6H4 – P). ESI-MS(?)m/z: 995.0 ([M-3 Ph]?, calc.: 994.9). IR (KBr, cm-1):1973 versus, m(C:O).

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Arcau, Julia; Ferrer, Montserrat; Aguilo, Elisabet; Rodriguez, Laura; Transition Metal Chemistry; vol. 42; 1; (2017); p. 57 – 67;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

13991-08-7, 1,2-Bis(diphenylphosphino)benzene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a glovebox, a vial was charged with 1,2-bis(diphenylphosphino)benzene (0.200 g, 0.45 mmol) and 4-trifluoromethylpyrazole (0.061 g, 0.45 mmol). Toluene (5 mL) was added, followed by a mesitylcopper(I) solution (0.068 g, 0.3733 mmol, in 5 mL toluene). The resulting yellow solution was heated at 60C for 15 hours. The mixture was cooled, and concentrated, and washed with hexanes (3×10 mL), to provide a material that was primarily the desired product. The mixture was further washed with toluene (2 x 2 mL), and dried to afford the title complex, as a yellow solid (144 mg). Pale yellow crystals were grown out of a concentrated toluene solution. Single crystal X-Ray diffraction studies supported the ChemDraw structure shown above.

13991-08-7, 13991-08-7 1,2-Bis(diphenylphosphino)benzene 498379, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; DOW GLOBAL TECHNOLOGIES LLC; LAITAR, David S.; CLARK, Thomas P.; RACHFORD, Aaron A.; MUKHOPADHYAY, Sukrit; DE VRIES, Timothy S.; DEVORE, David D.; (31 pag.)WO2016/57441; (2016); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate