Category: 13689-19-5

New learning discoveries about 13689-19-5

13689-19-5, The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13689-19-5,Tricyclohexylphosphine oxide,as a common compound, the synthetic route is as follows.

General procedure: Triphenylphosphine oxide or sulfide (1 mmol), dry hexane (1 mL), and Ic (1 mmol) were added to a Schlenk tube under the atmosphere of nitrogen. The reaction was carried out at room temperature for 10 min and monitored by TLC. Upon completion of the process the reaction mixture was filtered by silica gel and washed several times with ethyl acetate. Ethyl acetate was evaporated and the residue purified by flash chromatography on silica gel with pure cyclohexane toafford the desired phosphine. The yield was determined by GC without additional purification.

13689-19-5, The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Yang, Shuyan; Han, Xinxin; Luo, Minmin; Gao, Jing; Chu, Wenxiang; Ding, Yuqiang; Russian Journal of General Chemistry; vol. 85; 5; (2015); p. 1156 – 1160; Zh. Obshch. Khim.;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Analyzing the synthesis route of 13689-19-5

13689-19-5, 13689-19-5 Tricyclohexylphosphine oxide 26187, achiral-phosphine-ligands compound, is more and more widely used in various fields.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13689-19-5,Tricyclohexylphosphine oxide,as a common compound, the synthetic route is as follows.

General procedure: The same general procedure was adopted for the synthesis of all the complexes. The lanthanide bromide and tricyclohexylphosphineoxide were dissolved in hot ethanol. Heating was continued for 1 h during which time, in some cases, small quantities of crystalline material formed. Either cooling to room temperature followed by standing for 16 h or on prolonged standing and slow evaporation of the solution afforded crystalline materials. The crystals were filtered, washed with ethanol and dried at the pump. Representative syntheses and characterisations are described below.

13689-19-5, 13689-19-5 Tricyclohexylphosphine oxide 26187, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Bowden, Allen; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 91; (2015); p. 110 – 119;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Simple exploration of 13689-19-5

13689-19-5, As the paragraph descriping shows that 13689-19-5 is playing an increasingly important role.

13689-19-5, Tricyclohexylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The same general procedure was adopted for the synthesis of all the complexes. The lanthanide bromide and tricyclohexylphosphineoxide were dissolved in hot ethanol. Heating was continued for 1 h during which time, in some cases, small quantities of crystalline material formed. Either cooling to room temperature followed by standing for 16 h or on prolonged standing and slow evaporation of the solution afforded crystalline materials. The crystals were filtered, washed with ethanol and dried at the pump. Representative syntheses and characterisations are described below.

13689-19-5, As the paragraph descriping shows that 13689-19-5 is playing an increasingly important role.

Reference£º
Article; Bowden, Allen; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 91; (2015); p. 110 – 119;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

New learning discoveries about 13689-19-5

13689-19-5, The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13689-19-5,Tricyclohexylphosphine oxide,as a common compound, the synthetic route is as follows.

General procedure: The same general procedure was adopted for the synthesis of all the complexes. The lanthanide bromide and tricyclohexylphosphineoxide were dissolved in hot ethanol. Heating was continued for 1 h during which time, in some cases, small quantities of crystalline material formed. Either cooling to room temperature followed by standing for 16 h or on prolonged standing and slow evaporation of the solution afforded crystalline materials. The crystals were filtered, washed with ethanol and dried at the pump. Representative syntheses and characterisations are described below.

13689-19-5, The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Bowden, Allen; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 91; (2015); p. 110 – 119;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Brief introduction of 13689-19-5

13689-19-5 Tricyclohexylphosphine oxide 26187, achiral-phosphine-ligands compound, is more and more widely used in various.

13689-19-5, Tricyclohexylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The same general procedure was adopted for the synthesis of all the complexes. The lanthanide chloride and tricyclohexylphosphine oxide were dissolved in hot ethanol. Heating was continued for 1h and the solution was allowed to slowly evaporate at room temperature during which time crystalline material formed. The crystals were filtered, washed with cold ethanol and dried at the pump.

13689-19-5 Tricyclohexylphosphine oxide 26187, achiral-phosphine-ligands compound, is more and more widely used in various.

Reference£º
Article; Lees, Anthony M.J.; Platt, Andrew W.G.; Polyhedron; vol. 67; (2014); p. 368 – 372;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Downstream synthetic route of 13689-19-5

The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

13689-19-5, Tricyclohexylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 296.4 mg of tricyclohexylphosphorus oxide and 188.5 mg of DyCl3 ¡¤6H2O was added to a beaker, 15 mL of ethanol and 5 mL of water were added, and the mixture was stirred at room temperature for 4 hours. Then, the mixed solution was allowed to stand at room temperature for 3 days to obtain colorless rectangular crystals. The resulting crystals were washed with iced ethanol to purify the resulting product. The calculated yield based on the metal Dy was 52%.

The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Nankai University; Cheng Peng; Wang Yuxia; Shi Wei; (8 pag.)CN107556341; (2018); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Downstream synthetic route of 13689-19-5

The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

13689-19-5, Tricyclohexylphosphine oxide is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

2. Conversion of Tricyclohexylphosphine Oxide to Tricyclohexylphosphine Hydrochloride and Tricyclohexylphosphine; The apparatus used was a 250 ml flask with Teflon paddle stirrer, thermometer, unimmersed gas introduction tube with rotameter and excess pressure release valve (0.1 bar), a reflux cooler with cryostat and downstream dry ice cooler and an NaOH scrubbing tower. The reflux condenser was cooled to -15 C. The flask was initially charged with 8.0 g (0.027 mol) of tricyclohexylphosphine oxide in 60 ml of anhydrous toluene at room temperature, and the phosgene introduction was commenced. The initially clear colorless solution became cloudy immediately and an exothermic reaction set in, which could be controlled by throttling the phosgene introduction such that the temperature of the reaction mixture did not exceed 38 C. In addition, gas evolution set in. The phosgene introduction was continued until the gas evolution had ended (11.1 g; 0.112 mol of phosgene). Subsequently, the reaction mixture was stirred for another 30 minutes, while the temperature fell to 25 C. To remove excess phosgene, the mixture was heated to 40 C. with introduction of nitrogen for 240 minutes, and then further nitrogen was introduced at room temperature overnight for complete removal of phosgene. After adding 50 ml of toluene and stirring for 30 minutes, the flask contents (130 g) were transferred to a miniautoclave in a glove box under argon, and the autoclave was purged twice with 150 bar of nitrogen and then twice with 150 bar of hydrogen. The reaction mixture was heated to 160 C. with stirring and 100 bar of hydrogen were injected. After 48 hours, within which the pressure fell to 97 bar, the mixture was cooled and decompressed. The white flaky precipitate formed was filtered off under argon and washed twice with 10 ml of toluene each time. After the solvent had been removed under reduced pressure, 7.4 g (86% of theory) of tricyclohexylphosphine hydrochloride were obtained as a white solid.31P NMR (1H-coupled) (145 MHz; toluene-d8): delta=28.00 (d, JP-H=440 Hz).Elemental analysis (dihydrochloride): C18H35Cl2PCalculated: C, 60.8; H, 10.5; P, 8.7.Found: C, 61.1; H, 10.2; P, 8.4.

The synthetic route of 13689-19-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Basf SE; US2010/137643; (2010); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate