Category: 12150-46-8

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

To a dichloromethane solution (20cm3) of [PtCl2(PhCN)2] (100 mg, 0.21 mmol), a solution of dppf (118 mg, 0.21 mmol) in dichloromethane was added. The resulting mixture was kept on stirring for 4 hours at room temperature. Solvent was evaporated under reduced pressure and residue was washed thoroughly with hexane followed by diethyl ether to remove excess phosphine. The residue was extracted with dichloromethane, filtered and passed through a Florisil Column. The ensuing solution at room temperature resulted yellow crystals (yield 152 mg, 87percent). Anal. Calcd. for C34H28P2FePtCl2: C, 49.78; H, 3.44percent. Found: C, 49.76; H, 3.46percent. 1H NMR (CDCl3) delta: 4.19 (br, 4H, C5H4), 4.37 (br, 4H, C5H4), 7.37?7.47 (m, Ph), 7.86 (br, Ph), 7.67-7.61 (m, Ph); 31P{1H}NMR (CDCl3) delta?:13.1 [1J(Pt-P) = 3776 Hz] ppm.

12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Article; Chauhan, Rohit Singh; Cordes, David B.; Slawin, Alexandra M.Z.; Yadav, Seema; Dash, Chandrakanta; Inorganica Chimica Acta; vol. 478; (2018); p. 125 – 129;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a nitrogen filled glove box, [(1tBuIndenyl)Pd(,1Cl)]2 (100 mg, 0.16 mmol) and 1,1?-bis(diphenylphosphino)ferrocene (DPPF) (177 mg, 0.32 mmol) were added to a 100 mL Schlenk flask. Methanol (20 mL) was added and the mixture was stirred at roomtemperature for 2 hours. During this time, the mixture became homogenous with a deep red color. The flask was opened to air and the solvent was removed with a rotary evaporator to yield a red oil. Pentane was added, followed by sonication; vacuum filtration produced a red crystalline solid (225 mg, 81percent).

12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Patent; YALE UNIVERSITY; HAZARI, Nilay; MELVIN, Patrick; HRUSZKEWYCZ, Damian; (92 pag.)WO2016/57600; (2016); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

The solutions of (0.0256 g, 0.1 mmol) of H2dzin 10 cm3 of methanol, (0.1 mmol, 0.0233 g) ofMnCl2.6H2O in 10 cm3 of methanol) and (0.0554 g,0.1mmol of 1,1′-bis(diphenyl phosphine) ferrocene(dppf) were mixed and refluxed at 55 oC for 2 h to give brown colored precipitate and the solutionswas filtered and finally it was dried in an open air.Yield=81percent, d.p= 238¡ãC. Anal. Calc. percent for C47 H41 ClN4 P2Mn S Fe:C, 62.58; H, 4.58; N, 6.21, S, 3.55, Mn,6.09, Cl, 3,93 .Found percent: C, 62.87, H, 4.82; N, 6.53, S;3.88, Mn; 6.27, Cl.4.11.

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Mohamad, Hikmat Ali; Oriental Journal of Chemistry; vol. 34; 4; (2018); p. 1919 – 1925;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Complex 1 (0.112 g, 0.20 mmol) was dissolved in dryMeCN (20 ml) under argon, and Me3NO2H2O (0.022 g,0.20 mmol) was added. The color of the solution changed from red to brown immediately. After stirring at room temperature for 0.5 h, the resulting solution was mixedwith dppf (0.056 g, 0.10 mmol) and stirred for 3 h at the room temperature. The solvent was removed on a rotary evaporator, and the residue was subjected to preparativeTLC separation using CH2Cl2/petroleum ether (v/v = 1:1)as the eluent. From the main red band, complex 3 wasobtained as a red solid (0.072 g, 81 percent). IR (KBr disk cm-1): mC:O 2036 (vs), 1973 (vs), 1922 (m). 1H NMR(400 MHz, CDCl3, ppm): 1.67 (s, 6 H, 2 CH, 4 SCHaHe),2.22 (s, 4 H, 4 SCHaHe), 4.22 (s, 4 H, C5H4), 4.46 (s, 4 H,C5H4), 6.35 (s, 4 H, C6H5), 7.12 (s, 6 H, C6H5), 7.35 (m, 12H, C6H5), 7.59 (s, 8 H, C6H5). 31P NMR (161.9 MHz,CDCl3, 85 percent H3PO4, ppm): 55.1 (s). Anal. Calc. for C68-H62Fe5O10P2Se4: C, 48.2; H, 3.7. Found: C, 48.4; H, 3.4 percent.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Li, Chang-Gong; Cui, Mao-Jin; Xue, Feng; Zhu, Yong; Li, Yong-Fang; Shang, Jing-Yan; Niu, Hong-Ying; Transition Metal Chemistry; vol. 40; 5; (2015); p. 493 – 500;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A degassed dichloromethane (25.0?mL) solution of [RuCl2(PPh3)3] (96?mg; 0.10?mmol) and dppf (60.0?mg; 0.11?mmol), in a Schlenk flask, was stirred for 30?min followed by the addition of 0.10?mmol of the polypyridyl ligand. After 30?min of stirring the resulting solution was concentrated until ca. 5?mL and addition of 10?mL of diethyl ether afforded a solid, which was collected by filtration, washed with diethyl ether and dried under vacuum.

12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Article; Davila-Rodriguez, Maria?Jose; Barolli, Joao Paulo; de Oliveira, Katia Mara; Colina-Vegas, Legna; da Silva Miranda, Fabio; Castellano, Eduardo Ernesto; Von Poelhsitz, Gustavo; Batista, Alzir Azevedo; Archives of Biochemistry and Biophysics; vol. 660; (2018); p. 156 – 167;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

The solutions of a (0.0256 g, 0.1 mmol) ofH2dz in 10 cm3 of methanol, (0.1 mmol, 0.0273 g) ofCoCl2.6H2O in a10 cm3 of methanol) and (0.0554 g,0.1 mmol of 1,1′-bis(diphenylphosphine) ferrocene(dppf) were mixed and refluxed at 55 oC for 2 h togive brown colored precipitate and the solutionswas filtered and finally it was dried in an openair. Yield= 76percent, d.p= 288¡ãC. Anal. Calc.percent for C47H41 Cl N4 P2 Co S Fe:C, 62.30; H, 4.56; N, 6.18,S, 3.54, Co, 6.50, Cl, 3.91. Found percent: C, 61.95; H,4.62; N, 6.48, S; 3.85, Co; 6.73,Cl, 4.01. 1H-NMR(d6-DMSO) delta:7.78(4H,d), 7.42(4H,t), 7.28 ? 7.38(mH), 11.61(1H). The Proposed GeometricalStructure shown in Figure 1.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Mohamad, Hikmat Ali; Oriental Journal of Chemistry; vol. 34; 4; (2018); p. 1919 – 1925;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

The heteroleptic nickel, palladium and platinum complexes (1?10) were prepared according to the general procedure shown in Scheme 1. To a stirring 15 ml methanolic solution of the ligand K2(p-CH3C6H4SO2N=CS2)¡¤2H2O (0.18 g, 0.5 mmol), K2(p-ClC6H4SO2N=CS2)¡¤2H2O (0.19 g, 0.5 mmol), K2(p-BrC6H4SO2N=CS2)¡¤2H2O (0.21 g, 0.5 mmol) or K2C2H5OCO(CN)CCS2 (0.13 g, 0.5 mmol) a 10ml aqueous solution of NiCl2¡¤6H2O (0.12 g, 0.5 mmol), K2PdCl4 (0.163 g, 0.5 mmol) or K2PtCl4 (0.21 g, 0.5 mmol) was added and in each case the reaction mixture was stirred for half an hour to get a clear solution. To this 25 ml solution was added a 10 ml dichloromethane solution of 1,1?-bis(diphenylphosphino)ferrocene (0.28 g, 0.5 mmol) with vigorous stirring and then further stirred for 12 h in the case of Ni and 24 h for Pd and Pt complexes. The volume of the reaction mixtures were reduced to 15 ml on rotary evaporator and the solid products thus obtained were filtered off and washed with H2O?CH3OH (40:60 v/v) and dried in vacuo over calcium chloride., 12150-46-8

The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Singh, Santosh K.; Chauhan, Ratna; Diwan, Kiran; Drew, Michael G.B.; Bahadur, Lal; Singh, Nanhai; Journal of Organometallic Chemistry; vol. 745-746; (2013); p. 190 – 200;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

General procedure: A degassed dichloromethane (25.0?mL) solution of [RuCl2(PPh3)3] (96?mg; 0.10?mmol) and dppf (60.0?mg; 0.11?mmol), in a Schlenk flask, was stirred for 30?min followed by the addition of 0.10?mmol of the polypyridyl ligand. After 30?min of stirring the resulting solution was concentrated until ca. 5?mL and addition of 10?mL of diethyl ether afforded a solid, which was collected by filtration, washed with diethyl ether and dried under vacuum.

12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Davila-Rodriguez, Maria?Jose; Barolli, Joao Paulo; de Oliveira, Katia Mara; Colina-Vegas, Legna; da Silva Miranda, Fabio; Castellano, Eduardo Ernesto; Von Poelhsitz, Gustavo; Batista, Alzir Azevedo; Archives of Biochemistry and Biophysics; vol. 660; (2018); p. 156 – 167;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

12150-46-8, 1,1-Bis(diphenylphosphino)ferrocene is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

DPPF (55 mg, 0.1 mmol) was added to a rapidly stirred, 10 mlCH2Cl2 suspension of RuCl2(PPh3)3 (96 mg, 0.1 mmol). A colorchange from purple-black to red was observed within a few minutes.The solutionwas stirred for 30 min, then a CH2Cl2 solution of2-aminopyridine (9.4 mg, 0.1 mmol) was added, giving an immediatecolor change to yellow-green. After a further 30 min, thesolvent was removed in vacuo and 5ml of diethyl ether (Et2O) wereadded. The yellow product was filtered off, washed twice withether (2 5 ml), and then dried under vacuum.

12150-46-8, The synthetic route of 12150-46-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Ge, Sai; Zhang, Jin; Zhao, Jianguo; Ulhaq, Imran; Ma, Guibin; McDonald, Robert; Journal of Organometallic Chemistry; vol. 879; (2019); p. 7 – 14;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.

General procedure: The synthesis is similar to 2, with PPh3 being replaced by dppf(1.1 g, 2.0 mmol). The residue was purified by column chromatographyon silica gel (eluent: CH2Cl2/CH3OH, 30:1, V/V) to give abrown-yellow solid. Yield: 0.75 g, 72percent. 1H NMR (500 MHz, CDCl3)d 9.18 (d, J 8.2 Hz, 2H, ePhH), 8.63 (d, J 8.5 Hz, 2H, ePhH), 8.08(d, J 8.3 Hz, 2H, ePhH), 7.73e7.60 (m, 10H, ePhH), 7.56 (td, J 7.3,1.2 Hz, 4H, ePhH), 7.49e7.40 (m, 8H, ePhH), 6.29 (d, J 8.4 Hz, 2H,ePhH), 4.49 (s, 4H, eCpH), 4.20 (dd, J 8.2, 6.2 Hz, 8H, eCH2CH2e,eCpH), 1.73 (dt, J 15.2, 7.6 Hz, 4H, eCH2CH2e), 1.52e1.42 (m, 4H,eCH2CH2e), 0.99 (t, J 7.4 Hz, 6H, eCH2CH3). 13C NMR (125 MHz,Scheme 1.CDCl3) d 165.15, 164.40, 157.03, 133.29, 132.50, 131.90, 131.82, 131.31,131.17, 130.58, 129.82, 129.42, 129.23, 128.98, 128.91, 128.81, 124.08,122.48, 115.10, 114.99, 109.74, 74.39, 39.87, 30.39, 29.68, 20.46,13.90. 31P NMR (200 MHz, CDCl3) d 9.40. MS calcd for C66H56Fe-N4O5P2Na [MNa]: 1109.31, found: 1109.4., 12150-46-8

As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.

Reference£º
Article; Xu, Shou De; Fang, Cheng Hui; Tian, Guang Xuan; Chen, Yi; Dou, Ye Hong; Kou, Jun Feng; Wu, Xiang Hua; Journal of Molecular Structure; vol. 1102; (2015); p. 197 – 202;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate