Category: 1079-66-9

In an article, published in an article, once mentioned the application of 1079-66-9, Name is Chlorodiphenylphosphine,molecular formula is C12H10ClP, is a conventional compound. this article was the specific content is as follows.Computed Properties of C12H10ClP

A kind of sphingomyelin synthase inhibitor, its preparation method and application thereof (by machine translation)

The invention provides general formula (I) compound of formula, its pharmaceutically acceptable salts or stereoisomers, wherein X, Y, M, Z, R and Ar respectively as defined in the specification. The invention also provides a composition comprising a therapeutically effective amount of at least one of the foregoing general formula (I) compounds of formula, its pharmaceutically acceptable salts or stereoisomers, and the above-mentioned compound, its pharmaceutically acceptable salts or stereoisomers, or the above-mentioned pharmaceutical composition in preparation for the prevention and/or treatment of sphingomyelin level abnormal increase of the disease caused by the use of the medicament. The invention of the general formula (I) compound of formula, its pharmaceutically acceptable salts or stereoisomers, can selectively inhibit sphingomyelin synthase, internal and external pharmacodynamic effects are significant, the safety is high. (by machine translation)

Do you like my blog? If you like, you can also browse other articles about this kind. Computed Properties of C12H10ClP. Thanks for taking the time to read the blog about 1079-66-9

Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Electric Literature of 1079-66-9. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 1079-66-9, Name is Chlorodiphenylphosphine

PROCESS FOR THE REDUCTION OF NITRO DERIVATIVES TO AMINES

Disclosed is a novel process for the reduction of nitro groups to amino derivatives, based on the use of trichlorosilane and an organic base, which is efficient from the chemical standpoint and of wide general applicability.

If you are hungry for even more, make sure to check my other article about 1079-66-9. Electric Literature of 1079-66-9

Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

In an article, published in an article, once mentioned the application of 1079-66-9, Name is Chlorodiphenylphosphine,molecular formula is C12H10ClP, is a conventional compound. this article was the specific content is as follows.category: chiral-phosphine-ligands

Pharmaceutical composition and method for treating cardiovascular diseases using substituted anilides and sulfonamides

A novel pharmaceutical composition and method is disclosed for the treatment of cardiovascular diseases, e.g. myocardial ischemia and/or arrhythmia. The method and composition include an effective amount of a compound of the formula STR1 wherein X, Y, R, R1, A, A’, m, n, p, p’ and B are as defined herein.

Do you like my blog? If you like, you can also browse other articles about this kind. category: chiral-phosphine-ligands. Thanks for taking the time to read the blog about 1079-66-9

Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 1079-66-9, Name is Chlorodiphenylphosphine, HPLC of Formula: C12H10ClP.

A novel method for preparing isocyanides from N-substituted formamides with chlorophosphate compounds

Treatment of N-substituted formamides with chlorophosphate compounds such as PhOPOCl2, EtOPOCl2, Me2NPOCl2, and (PhO)2POCl and tertiary amines such as triethylamine, pyridine, and N,N-diisopropylethylamine produced the corresponding isocyanides in high yields. This method can be used to prepare various alkyl and aryl isocyanides. Georg Thieme Verlag Stuttgart ¡¤ New York.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.HPLC of Formula: C12H10ClP. In my other articles, you can also check out more blogs about 1079-66-9

Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 1079-66-9, Name is Chlorodiphenylphosphine, Application In Synthesis of Chlorodiphenylphosphine.

Total syntheses of Tardioxopiperazine A, Isoechinulin A, and Variecolorin C

Chemical equations presented. First total syntheses of the isoechinulin-type alkaloids: Tardioxopiperazine A, Isoechinulin A, and Variecolorin C have been achieved from a common key intermediate 5, which was derived from a regiocontrolled Stille cross-coupling reaction of an allylindium reagent.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application In Synthesis of Chlorodiphenylphosphine. In my other articles, you can also check out more blogs about 1079-66-9

Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

Related Products of 1079-66-9, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 1079-66-9, C12H10ClP. A document type is Patent, introducing its new discovery.

SUBSTITUTED 5-CARBOXYAMIDE PYRAZOLES AND [1,2,4]TRIAZOLES AS ANTIVIRAL AGENTS

The present invention provides compounds of formula I wherein X, Y, R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provided. (I)

If you are hungry for even more, make sure to check my other article about 1079-66-9. Related Products of 1079-66-9

Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1079-66-9,Chlorodiphenylphosphine,as a common compound, the synthetic route is as follows.

If the process is carried out in such a manner that the mixture is brought to room temperature after completion of the dropwise addition of chloro(diphenyl)phosphine, then kept under reflux for 12 hours and then worked up as above after cooling, 195 g of ethyl diphenylphosphinite are obtained. This corresponds to a yield of 94% of theory.

1079-66-9, As the paragraph descriping shows that 1079-66-9 is playing an increasingly important role.

Reference£º
Patent; Hoechst Aktiengesellschaft; US5705669; (1998); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

1079-66-9, Chlorodiphenylphosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a 50 mL three-necked flask equipped with a reflux condenser and a stirrer, 0.32 g (13 mmol) of metal magnesium powder and 3.3 mg (0.013 mmol) of iodine were charged under an argon stream.Stir for 8 hours. ThenA solution prepared by dissolving 1.9 g (11 mmol) of 2-bromotoluene in 10 ml of tetrahydrofuran (THF) was dropped from a dropping funnel.After completion of dropping, the mixture was stirred for 3 hours under reflux of THF. *The obtained 2-toluylmagnesium bromide in THF was cooled to -78 C.,ChlorodiphenylphosphineAfter adding a solution of 3.3 g (15 mmol) dissolved in 2 ml of THF, the temperature was raised to room temperature,Stir for 8 hours.The chloromagnesium bromide precipitated from the obtained reaction mixture was filtered off with a glass filter and washed with 5 ml of pure water and 5 ml of saturated saline. This crude diphenyl (2-toluyl) phosphine solution was dried over magnesium sulfate, and then THF was distilled off, followed by vacuum drying to obtain yellow oily crude diphenyl (2-toluyl) phosphine. The resulting crude diphenyl (2-tolyl) phosphine was purified by flash silica gel chromatography (ethyl acetate / n-hexane)Diphenyl (2-toluyl) phosphine0.88 g (3.2 mmol) was obtained.

1079-66-9, 1079-66-9 Chlorodiphenylphosphine 66180, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Patent; Tosoh Corporation; Tokyo University of Science; Kuramochi, Yusuke; Satake, Shoji; Hara, Oharu; (28 pag.)JP2019/142829; (2019); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1079-66-9,Chlorodiphenylphosphine,as a common compound, the synthetic route is as follows.

Under nitrogen protection,1L three bottles,From 29.3 g of 2-bromotoluene,5 g of magnesium turnings and 400 mlOf anhydrous methyl tetrahydrofuran to produce a Grignard reagent,Refluxed for 6 hours,To the room temperature, 2 g of tetrakis (triphenylphosphine) palladium was added,Stirred for 10 minutes,40 g of diphenylphosphonium chloride was added dropwise at room temperature,The reaction was refluxed for 6 hours.To the reaction solution was added dropwise 200 mL of an ice-water bathThe saturated aqueous ammonium chloride solution was quenched,Liquid separation,The organic phase is dissolved,Add methanol crystallization,Filtration gave 45 g of white 2-diphenylphosphine toluene,Yield 95%.

1079-66-9, The synthetic route of 1079-66-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Panjin Gelin Kaimo Technology Co., Ltd.; Rao, Zhihua; Gong, Ningrui; (12 pag.)CN105859774; (2016); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1079-66-9,Chlorodiphenylphosphine,as a common compound, the synthetic route is as follows.

To an ice-cold solution of methyl alcohol (6 mL, 1.2 mmol) in toluene (13 mL), a solution of chlorodiphenylphosphine (0.25 mL, 1.38 mmol) in toluene (3 mL) was added dropwise. After 40 min stirring, azide 5 (440 mg, 1.2 mmol) was added as a solid. The obtained mixture was heated at 60 C for 40 min and then kept at room temperature for 12 h. The collected precipitate was analytically pure product 6 (300 mg, 48%). Crystals suitable for X-ray diffraction were obtained by crystallization from MeCN-DMF (3 : 1). M.p. 245 C. Found (%): P, 5.66. C27H21BrN3O2. Calculated (%): P, 5.70. IR (KBr), nu/cm-1: 1706 (C=O), 1606 (C=N), 3346 (NH). 31P NMR (DMSO-d6), delta: 23.45. 1H NMR (DMSO-d6), delta: 4.72-4.76 (m, 1 H, CHNP); 6.43-7.97 (m, 8 H, Ar); 11.01 (s, 1 H, NH).

1079-66-9, 1079-66-9 Chlorodiphenylphosphine 66180, achiral-phosphine-ligands compound, is more and more widely used in various fields.

Reference£º
Article; Gololobov, Yu. G.; Krasnova, I. Yu.; Barabanov; Fedyanin; Andronati; Pavlovskii; Russian Chemical Bulletin; vol. 64; 1; (2015); p. 233 – 236; Izv. Akad. Nauk, Ser. Khim.; 1; (2015); p. 233 – 236,4;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate