With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1608-26-0,N,N,N’,N’,N”,N”-Hexamethylphosphinetriamine,as a common compound, the synthetic route is as follows.
Trisdimethylaminophosphine 1 (1 mmol)was added to a solution of isatin imine 2a (1 mmol) in dry toluene (30mL), and the resulting mixture was stirring at room temperature for 4 h (TLC) in the presence of atmospheric moisture.[24] After evaporation of the volatile material under reduced pressure, the residue was subjected to silica-gel column chromatography to give the product 4a., 1608-26-0
The synthetic route of 1608-26-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Arsanious, Mona Hizkial Nasr; Maigali, Soher Said; Synthetic Communications; vol. 44; 2; (2014); p. 202 – 214;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate