Synthesis of bornene-2,2′-diamino-1,1′-binaphthalene conjugates in palladium-catalysed aminocarbonylations was written by Mikle, Gabor;Boros, Borbala;Kollar, Laszlo. And the article was included in Tetrahedron: Asymmetry in 2016.Product Details of 77876-39-2 This article mentions the following:
Palladium-catalyzed aminocarbonylation of a terpenoic iodoalkene (2-iodobornene) model compound with both enantiomerically pure and racemic 2,2′-diamino-1,1′-binaphthalene (BINAM) as the N-nucleophile was carried out. All of the diastereoisomers of the monocarboxamide (N-bornenyl carboxamide) and dicarboxamide (N,N’-dinorbornenylcarboxamide) derivatives were synthesized. The diastereoselectivities of the aminocarbonylation were investigated in both cases: either racemic BINAM was used as the N-nucleophile in the aminocarbonylation of enantiomerically pure 2-iodobornene or racemic iodobornene was aminocarbonylated with enantiomerically pure BINAM with moderate diastereoselectivities. In this way, all possible diastereoisomers of binaphthalene-bornene conjugates were synthesized in moderate to high yields by asym. (diastereoselective) aminocarbonylation. In the experiment, the researchers used many compounds, for example, (2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) (cas: 77876-39-2Product Details of 77876-39-2).
(2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) (cas: 77876-39-2) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Product Details of 77876-39-2
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis