Direct visual detection of the stereoselectivity of a catalytic reaction was written by Eelkema, Rienk;van Delden, Richard A.;Feringa, Ben L.. And the article was included in Angewandte Chemie, International Edition in 2004.Reference of 252288-04-3 This article mentions the following:
Color vision: the enantiomeric excess of the products of an enantioselective catalytic reaction can be determined by a liquid-crystal-based color test. After a simple workup, doping of the reaction product into a liquid crystal affords brightly colored LC phases, with colors depending on the enantiomeric excess of the product. In the experiment, the researchers used many compounds, for example, (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3Reference of 252288-04-3).
(11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3) belongs to chiral phosphine ligands. Generally, the efficiency of nucleophilic phosphine catalysis often depends on the nature of the tertiary phosphine. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Reference of 252288-04-3
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis