Ogaki, Shuichiro; Shibata, Yu; Noguchi, Keiichi; Tanaka, Ken published the artcile< Enantioselective Synthesis of Axially Chiral Hydroxy Carboxylic Acid Derivatives by Rhodium-Catalyzed [2 + 2 + 2] Cycloaddition>, Application of C44H40P2, the main research area is naphthalenepropynoic acid derivative diyne chiral rhodium bisphosphine catalyst cycloaddition; arylnaphthalene hydroxy carboxylic acid derivative regioselective stereoselective preparation; axially chiral arylnaphthalene regioselective stereoselective preparation.
Axially chiral hydroxy carboxylic acid derivatives were successfully synthesized with high yields and ee values by the cationic rhodium(I)/axially chiral biaryl bisphosphine complex-catalyzed enantioselective [2+2+2] cycloaddition of diynes with naphthalenepropynoic acid derivatives Axially chiral hydroxy and dihydroxy carboxylic acid derivatives, bearing the aryl group at the ortho-position of the alkoxycarbonyl group, were also synthesized with high regio- and enantioselectivity.
Journal of Organic Chemistry published new progress about Alkadiynes Role: RCT (Reactant), RACT (Reactant or Reagent) (derivatives). 139139-93-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Application of C44H40P2.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate