Saba, Tony; Li, Jianwei; Burnett, Joseph W. H.; Howe, Russell F.; Kechagiopoulos, Panagiotis N.; Wang, Xiaodong published the artcile< NADH Regeneration: A Case Study of Pt-Catalyzed NAD+ Reduction with H2>, Formula: C21H27N7Na2O14P2, the main research area is TEM hydrogenation catalyst platinum; NAD hydrogenation NMR NADH platinum magnesium catalyst nicotinamide silica.
This study shows the importance of resolving catalytic performance in the regeneration of the reduced form of NAD (NADH) through activity measurements based on NAD+ conversion and the closure of mass balance via byproduct quantification. This approach is applied to assess the performance of supported platinum catalysts with varying points of zero charge, utilizing H2 as a reductant. It was found that Pt/SiO2, which exhibits a net neg. charge under the reaction conditions, outperforms the neutral Pt/C and pos. charged Pt/MgO because of the favorable electrostatic attraction between the catalyst surface and pos. charged (+1) nicotinamide ring. NMR spectroscopy identifies side-products formed during NAD+ hydrogenation.
ACS Catalysis published new progress about Hydrogenation. 606-68-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C21H27N7Na2O14P2, Formula: C21H27N7Na2O14P2.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate