Zhang, Ze-Xin; Chen, Si-Cong; Jiao, Lei published the artcile< Total Synthesis of (+)-Minfiensine: Construction of the Tetracyclic Core Structure by an Asymmetric Cascade Cyclization>, Synthetic Route of 152140-65-3, the main research area is minfiensine synthesis asym cascade cyclization; monoterpene indole alkaloid core structure preparation asym cascade cyclization; alkaloids; cyclizations; natural products; palladium; total synthesis.
A new method for one-step construction of the tetracyclic core structure of the indole alkaloid (+)-minfiensine was developed utilizing a palladium-catalyzed asym. indole dearomatization/iminium cyclization cascade. An efficient total synthesis of (+)-minfiensine was realized using this strategy. The present method enables access to the common core structure of a series of monoterpene indole alkaloids, such as vincorine, echitamine, and aspidosphylline A.
Angewandte Chemie, International Edition published new progress about Cyclization, stereoselective. 152140-65-3 belongs to class chiral-phosphine-ligands, and the molecular formula is C54H42N2O2P2, Synthetic Route of 152140-65-3.
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Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate