de Vries, Andre H. M.; Mulders, Jan M. C. A.; Mommers, John H. M.; Henderickx, Huub J. W.; de Vries, Johannes G. published the article 《Homeopathic Ligand-Free Palladium as a Catalyst in the Heck Reaction. A Comparison with a Palladacycle》. Keywords: Heck arylation aryl bromide ligand free palladium catalyst; palladium acetate catalyst Heck arylation aryl bromide; palladacycle catalyst Heck arylation aryl bromide.They researched the compound: trans-Di-μ-acetatobis[2-[bis(2-methylphenyl)phosphino]benzyl]dipalladium( cas:172418-32-5 ).Related Products of 172418-32-5. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:172418-32-5) here.
Ligand-free Pd(OAc)2 can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %. At higher concentrations Pd black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free Pd in Heck reactions of aryl bromides. The method is extremely attractive for large scale-up production, and it has been scaled up to Kg quantities.
After consulting a lot of data, we found that this compound(172418-32-5)Related Products of 172418-32-5 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate