Reference of 564483-18-7. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 564483-18-7, Name is 2-(Dicyclohexylphosphino)-2′,4′,6′-tri-i-propyl-1,1′-biphenyl
The invention provides a synthetic method of an oxazoline compound represented as the formula (II). The synthetic method includes a step of carrying out a reaction to a compound represented as the following formula (I) with an iodine ether compound to generate the compound represented as the formula (II) in an organic solvent in the presence of a catalyst, an organic acid and an organic phosphine ligand, wherein R is H, a C1-C6 alkyl group, a C1-C6 alkoxyl group or halogen and n is an integer from 1 to 4. The synthetic method includes optimizing selection on the catalyst, the organic acid, the organic phosphine ligand, the iodine compound and the organic solvent to finally obtain a most preferably reaction system, by which the targeted product can be prepared at a high yield. The synthetic method is simple in post-treatment, is short in required time, is a convenient synthetic method for preparation and production of medical and chemical products and has a wide market prospect.
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Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate