17261-28-8, 2-(Diphenylphosphino)benzoic acid is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a round bottom flask were added 2-(diphenylphosphino)benzoic acid (17.94 mg, 0.058 mmol) and 3 mL of DMF. To the solution were added 1-O-(N,N’,N,N’tetramethyluronium)azabenzotriazoloxy hexafluorophosphate (26.73 mg, 0.070 mmol), 1-hydroxyazabenzotriazole (9.56 mg, 0.070 mmol), and diisopropylethylamine (45.4 mg, 0.0612 mL). After stirring the reaction mixture for 7 minutes, N-alpha-(6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinyl)lysine methyl ester hydrochloride (35.2 mg, 0.070 mmol) dissolved in 4 ml of DMF was added to the above mixture. The reaction mixture was stirred for 2 hours. The solvent was removed in vacuo and the resulting crude oil was subjected to HPLC purification using the method described above. The collected fractions were combined, and were lyophilized to give the product as a pale yellow solid. The yield was 29 mg (66percent) after HPLC purification., 17261-28-8
As the paragraph descriping shows that 17261-28-8 is playing an increasingly important role.
Reference£º
Patent; Liu, Shuang; US2005/8575; (2005); A1;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate