Synthetic Route of 787618-22-8, An article , which mentions 787618-22-8, molecular formula is C30H43O2P. The compound – Dicyclohexyl(2′,6′-diisopropoxy-[1,1′-biphenyl]-2-yl)phosphine played an important role in people’s production and life.
We describe the development of (eta3-1-tBu-indenyl)2(mu-Cl)2Pd2, a versatile precatalyst scaffold for Pd-catalyzed cross-coupling. Our new system is more active than commercially available (eta3-cinnamyl)2(mu-Cl)2Pd2 and is compatible with a range of NHC and phosphine ligands. Precatalysts of the type (eta3-1-tBu-indenyl)Pd(Cl)(L) can either be isolated through the reaction of (eta3-1-tBu-indenyl)2(mu-Cl)2Pd2 with the appropriate ligand or generated in situ, which offers advantages for ligand screening. We show that the (eta3-1-tBu-indenyl)2(mu-Cl)2Pd2 scaffold generates highly active systems for a number of challenging cross-coupling reactions. The reason for the improved catalytic activity of systems generated from the (eta3-1-tBu-indenyl)2(mu-Cl)2Pd2 scaffold compared to (eta3-cinnamyl)2(mu-Cl)2Pd2 is that inactive PdI dimers are not formed during catalysis.
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Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate