In an article, author is Yin, Xuemei, once mentioned the application of 7650-91-1, COA of Formula: C19H17P, Name is Benzyldiphenylphosphine, molecular formula is C19H17P, molecular weight is 276.31, MDL number is MFCD00014083, category is chiral-phosphine-ligands. Now introduce a scientific discovery about this category.
Enantioselective Palladium-Catalyzed Hydrofluorination of Alkenylarenes
Hydrofluorination of simple alkenes is an attractive strategy to prepare fluorine-containing molecules. However, the catalytic asymmetric hydrofluorination remains an ongoing challenge. Here, we describe a palladium(II)-catalyzed enantioselective hydrofluorination of alkenylarenes, by employing sulfoxide phosphine (SOP) as a chiral ligand, triarylphosphine as a secondary ligand, Selectfluor as a fluorine source, and trihexylsilane as a hydride source. Under the optimal reaction conditions, a range of chiral benzyl fluorides bearing different functional groups are obtained in good yields (up to 80%) with high enantiopurity (having an enantiomeric ratio of up to 94:6). Some mechanistic insight of this reaction is obtained using in situ one-and two-dimensional H-1-P-31 HMBC nuclear magnetic resonance spectroscopy and a catalytic cycle is proposed.
If you are interested in 7650-91-1, you can contact me at any time and look forward to more communication. COA of Formula: C19H17P.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate