Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Name: Tri-m-tolylphosphine, 6224-63-1, Name is Tri-m-tolylphosphine, molecular formula is C21H21P, belongs to chiral-phosphine-ligands compound. In a document, author is Wang, Haiyang, introduce the new discover.
Enantioselective [4+2] Annulation to the Concise Synthesis of Chiral Dihydrocarbazoles
A highly efficient phosphine-catalyzed enantioselective [4+2] annulation of allenoates with 3-nitroindoles or 3-nitrobenzothiophenes has been developed. The protocol represents a unique dearomatization-aromatization process to access functionalized dihydrocarbazoles or dihydrodibenzothiophenes with high optical purity (up to 97% ee) under mild reaction conditions. The synthetic utility of the highly enantioselective [4+2] annulation enables a concise synthesis of analgesic agent.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 6224-63-1. Name: Tri-m-tolylphosphine.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate