Copper-Catalyzed Regio- and Stereoselective Aminoboration of Alkenylboronates was written by Nishikawa, Daiki;Hirano, Koji;Miura, Masahiro. And the article was included in Organic Letters in 2016.Safety of (2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) This article mentions the following:
A Cu-catalyzed aminoboration of alkenyl dan boronates (dan = 1,8-diaminonaphthyl) with diboron reagents and hydroxylamines was developed. The reaction proceeds regio- and stereoselectively to form the corresponding β-boryl-α-aminoboronic acid derivatives of potent interest in medicinal chem. Addnl., the ligand-controlled syn/anti diastereoselectivity switching and preliminary asym. catalysis are also described. In the experiment, the researchers used many compounds, for example, (2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) (cas: 77876-39-2Safety of (2S,4S)-Pentane-2,4-diylbis(diphenylphosphine)).
(2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) (cas: 77876-39-2) belongs to chiral phosphine ligands. Many phosphine-catalyzed reactions have been developed for the syntheses of various biologically important acyclic and cyclic molecules. Asymmetric variants of these reactions have evolved relatively slowly. Most of these phosphines are acyclic, usually possess low nucleophilic activity, and generally display poor enantioselectivities for phosphine organocatalysis. Safety of (2S,4S)-Pentane-2,4-diylbis(diphenylphosphine)
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis