Month: February 2023

Trost, Barry M. et al. published their research in Angewandte Chemie, International Edition in 2012 | CAS: 174810-09-4

N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide) (cas: 174810-09-4) belongs to chiral phosphine ligands. Phosphine-catalyzed asymmetric reactions are now powerful and versatile tools for the construction of C–C, C–N, C–O, and C–S bonds and for the syntheses of functionalized carbocycles and heterocycles. Indeed, very little research on chiral tertiary phosphine-catalyzed asymmetric reactions occurred prior to the year 2000.Recommanded Product: N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide)

Enantioselective synthesis of tertiary α-hydroxyketones from unfunctionalized ketones: palladium-catalyzed asymmetric allylic alkylation of enolates was written by Trost, Barry M.;Koller, Raffael;Schaeffner, Benjamin. And the article was included in Angewandte Chemie, International Edition in 2012.Recommanded Product: N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide) This article mentions the following:

A highly regio- and enantioselective palladium-catalyzed decarboxylative allylic alkylation to access functionalized tertiary α-hydroxyketones from ketones is introduced. Starting from tetralone derivatives and benzosuberone, through O-acylation with allyl imidazolecarboxylates followed by epoxidation with m-CPBA, rearrangement by treatment with BF3·OEt2, enolationprotection, and palladium-catalyzed asym. allylic alkylation, a series of α-hydroxy benzocyclic ketone derivatives were obtained in good yields and excellent stereoselectivities. Finally, the corresponding α-hydroxy benzocyclic ketones could be generated by romoving the methoxymethyl (MOM) or benzyloxymethyl (BOM) protecting group. In the experiment, the researchers used many compounds, for example, N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide) (cas: 174810-09-4Recommanded Product: N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide)).

N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide) (cas: 174810-09-4) belongs to chiral phosphine ligands. Phosphine-catalyzed asymmetric reactions are now powerful and versatile tools for the construction of C–C, C–N, C–O, and C–S bonds and for the syntheses of functionalized carbocycles and heterocycles. Indeed, very little research on chiral tertiary phosphine-catalyzed asymmetric reactions occurred prior to the year 2000.Recommanded Product: N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide)

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Jiang, Quanbin et al. published their research in ChemCatChem in 2015 | CAS: 174467-31-3

(R,R)-2,2′-Bis[(R)-(N,N-dimethylamino)(phenyl)methyl]-1,1′-bis(diphenylphosphino)ferrocene (cas: 174467-31-3) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Recommanded Product: 174467-31-3

Copper-Catalyzed Tandem Asymmetric Borylation of β-Chloroalkyl Aryl Ketones and Related Compounds was written by Jiang, Quanbin;Guo, Tenglong;Yu, Zhengkun. And the article was included in ChemCatChem in 2015.Recommanded Product: 174467-31-3 This article mentions the following:

The Cu-catalyzed, one-pot tandem (asym.) borylation of β-chloroalkyl aryl ketones via the in situ generated acyclic enones with bis(pinacolato)diboron was achieved efficiently to reach up to 97% yield and 99% enantioselectivity for the formal sp3 C-Cl borylation products. The present methodol. provides an efficient alternative route to (chiral) alkylboron compounds In the experiment, the researchers used many compounds, for example, (R,R)-2,2′-Bis[(R)-(N,N-dimethylamino)(phenyl)methyl]-1,1′-bis(diphenylphosphino)ferrocene (cas: 174467-31-3Recommanded Product: 174467-31-3).

(R,R)-2,2′-Bis[(R)-(N,N-dimethylamino)(phenyl)methyl]-1,1′-bis(diphenylphosphino)ferrocene (cas: 174467-31-3) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Recommanded Product: 174467-31-3

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Touati, Ridha et al. published their research in Journal de la Societe Chimique de Tunisie in 2008 | CAS: 133545-16-1

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. Many phosphine-catalyzed reactions have been developed for the syntheses of various biologically important acyclic and cyclic molecules. Asymmetric variants of these reactions have evolved relatively slowly. Effective chiral catalysts for nucleophilic phosphine catalysis are scarce, seriously limiting the development of asymmetric variants. Application of 133545-16-1

Efficient synthesis of chiral 1,3-diols and of 1-substituted-propan-1-ols through asymmetric hydrogenation was written by Touati, Ridha;Ben Hassine, Bechir. And the article was included in Journal de la Societe Chimique de Tunisie in 2008.Application of 133545-16-1 This article mentions the following:

Asym. hydrogenations of an achiral β-keto ester using a chiral diphosphine-ruthenium catalyst to set the hydroxyl function in a stereo controlled manner were used in key-step towards the total synthesis of both enantiomers of secondary alcs. with excellent enantioselectivity (>99% ee) and high yields. In the experiment, the researchers used many compounds, for example, (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1Application of 133545-16-1).

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. Many phosphine-catalyzed reactions have been developed for the syntheses of various biologically important acyclic and cyclic molecules. Asymmetric variants of these reactions have evolved relatively slowly. Effective chiral catalysts for nucleophilic phosphine catalysis are scarce, seriously limiting the development of asymmetric variants. Application of 133545-16-1

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Kocovsky, Pavel et al. published their research in Journal of the American Chemical Society in 1999 | CAS: 134484-36-9

(S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9) belongs to chiral phosphine ligands. Many phosphine-catalyzed reactions have been developed for the syntheses of various biologically important acyclic and cyclic molecules. Asymmetric variants of these reactions have evolved relatively slowly. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Formula: C33H25OP

Palladium(II) Complexes of 2-Dimethylamino-2′-diphenylphosphino-1,1′-binaphthyl (MAP) with Unique P,Cσ-Coordination and Their Catalytic Activity in Allylic Substitution, Hartwig-Buchwald Amination, and Suzuki Coupling was written by Kocovsky, Pavel;Vyskocil, Stepan;Cisarova, Ivana;Sejbal, Jan;Tislerova, Iva;Smrcina, Martin;Lloyd-Jones, Guy C.;Stephen, Susanna C.;Butts, Craig P.;Murray, Martin;Langer, Vratislav. And the article was included in Journal of the American Chemical Society in 1999.Formula: C33H25OP This article mentions the following:

Reaction of 2-dimethylamino-2′-diphenylphosphino-1,1′-binaphthyl with (PhCN)2PdCl2 gave an unusual Cσ-Pd bonding mode complex I. The catalytic activity in allylic substitution, Hartwig-Buchwald Amination, and Suzuki coupling of I is described. The crystal structure of I and two related complexes were described. In the experiment, the researchers used many compounds, for example, (S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9Formula: C33H25OP).

(S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9) belongs to chiral phosphine ligands. Many phosphine-catalyzed reactions have been developed for the syntheses of various biologically important acyclic and cyclic molecules. Asymmetric variants of these reactions have evolved relatively slowly. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Formula: C33H25OP

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Han, Xinxin et al. published their research in Analytical and Bioanalytical Chemistry in 2007 | CAS: 37002-48-5

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Generally, the efficiency of nucleophilic phosphine catalysis often depends on the nature of the tertiary phosphine. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Category: chiral-phosphine-ligands

Preparation and evaluation of a new synthetic polymeric chiral stationary phase for HPLC based on the trans-9,10-dihydro-9,10-ethanoanthracene-(11S,12S)-11,12-dicarboxylic acid bis-4-vinylphenylamide monomer was written by Han, Xinxin;Wang, Chunlei;He, Lingfeng;Beesley, Thomas E.;Armstrong, Daniel W.. And the article was included in Analytical and Bioanalytical Chemistry in 2007.Category: chiral-phosphine-ligands This article mentions the following:

A new synthetic polymeric chiral stationary phase for liquid chromatog. was prepared via free-radical-initiated polymerization of trans-9,10-dihydro-9,10-ethanoanthracene-(11S,12S)-11,12-dicarboxylic acid bis-4-vinylphenylamide. The new polymeric chiral stationary phase (CSP) showed enantioselectivity for many chiral compounds in multiple mobile phases. High stability and sample capacities were observed on this polymeric chiral stationary phase. Mobile phase components and additives affected chiral separation greatly. This new synthetic chiral stationary phase is complementary to two other related com. available CSPs: the P-CAP and P-CAP-DP columns. Interactions between the chiral stationary phase and analytes that lead to retention and chiral recognition include hydrogen bonding, dipolar, and π-π interactions. Repulsive (steric) interactions also contribute to chiral recognition. In the experiment, the researchers used many compounds, for example, (((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5Category: chiral-phosphine-ligands).

(((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine) (cas: 37002-48-5) belongs to chiral phosphine ligands. Generally, the efficiency of nucleophilic phosphine catalysis often depends on the nature of the tertiary phosphine. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Category: chiral-phosphine-ligands

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Wang, Qing et al. published their research in ACS Catalysis in 2022 | CAS: 134484-36-9

(S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Electric Literature of C33H25OP

Enantioselective Nickel-Catalyzed Si-C(sp2) Bond Activation and Migratory Insertion to Aldehydes: Reaction Scope and Mechanism was written by Wang, Qing;Zhong, Kang-Bao;Xu, Hao;Li, Shi-Nan;Zhu, Wei-Ke;Ye, Fei;Xu, Zheng;Lan, Yu;Xu, Li-Wen. And the article was included in ACS Catalysis in 2022.Electric Literature of C33H25OP This article mentions the following:

Transition-metal-catalyzed Si-C bond activation is one of the most important processes in both organosilicon chem. and homogeneous catalysis that is still rarely reported in the past decades, and the enantioselective versions based on transition-metal-catalyzed Si-C bond activation remain an ongoing challenge in asym. catalysis. Herein, the authors report a convenient and enantioselective Si-C bond cleavage-initiated [4 + 2] annulation of benzosilacyclobutenes with aldehydes, which provides an access to the direct synthesis of chiral six-membered oxasilacycles and their derivatives with high yields and enantioselectivities (up to 97% ee). The catalytic asym. reaction proceeds smoothly with the aid of a chiral TADDOL-derived phosphoramidite ligand and its chiral Ni complex with a suitable cavity. By switching the work-up of the reaction involved, the present strategy may be extended to subsequent downstream transformations of silyl ether-containing oxasilacycles to give chiral o-tolyl arylmethanols with high ees and quant. conversions. Exptl. results support that the strategy of Si-mediated organic synthesis controlled by Ni catalysis demonstrates a powerful potential for the facile synthesis of chiral alcs. and its drug-like derivatives Finally, mechanistic and computational studies of the Ni-catalyzed Si-C bond activation offer insights into the origin of the observed stereoselective outcome, and the d. functional theory calculation shows that the Ni-controlled Si-C(sp2) bond activation enables the controllable migratory insertion of benzaldehyde into the Ni-Si bond, which is recognized as the enantioselectivity-determining step. In the experiment, the researchers used many compounds, for example, (S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9Electric Literature of C33H25OP).

(S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Electric Literature of C33H25OP

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Zhou, Lujia et al. published their research in Chinese Journal of Chemistry in 2020 | CAS: 1595319-95-1

(R)-N-((S)-(2-(diphenylphosphaneyl)phenyl)(naphthalen-1-yl)methyl)-2-methylpropane-2-sulfinamide (cas: 1595319-95-1) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Trivalent phosphorus compounds called phosphines have a tetrahedral electron-group geometry which makes them structurally analogous to amines.Product Details of 1595319-95-1

Ming-Phos/Gold(I)-Catalyzed Stereodivergent Synthesis of Highly Substituted Furo[3,4-d][1,2]oxazines was written by Zhou, Lujia;Xu, Bing;Ji, Danting;Zhang, Zhan-Ming;Zhang, Junliang. And the article was included in Chinese Journal of Chemistry in 2020.Product Details of 1595319-95-1 This article mentions the following:

A gold(I)-catalyzed asym. intermol. tandem [3+3]-cyclization reaction of 2-(1-alkynyl)-2- alken-1-ones R1CCC(=CHR3)(C(O)R2) (R1 = Bu, Ph, 1-naphthyl, etc.; R2 = Me, Ph; R3 = Ph, 4-methylphenyl, 4-methoxyphenyl, 4-chlorophenyl, 4-bromophenyl) with nitrones R4N(=O)=CHR5 (R4 = Ph, 4-methylphenyl, 4-methoxyphenyl, 3-chlorophenyl; R5 = Ph, styryl, furan-2-yl, etc.) has been developed by using Ming-Phos as a chiral ligand. This method enables access to the stereodivergent synthesis of highly substituted furo[3,4-d][1,2]oxazines I and II in excellent efficiency and stereoselectivity (up to 99% yield, 99% ee, >20 : 1 dr). In the experiment, the researchers used many compounds, for example, (R)-N-((S)-(2-(diphenylphosphaneyl)phenyl)(naphthalen-1-yl)methyl)-2-methylpropane-2-sulfinamide (cas: 1595319-95-1Product Details of 1595319-95-1).

(R)-N-((S)-(2-(diphenylphosphaneyl)phenyl)(naphthalen-1-yl)methyl)-2-methylpropane-2-sulfinamide (cas: 1595319-95-1) belongs to chiral phosphine ligands. During the past two decades, tertiary phosphine catalysts have been applied extensively in a wide range of carbon–carbon and carbon–heteroatom bond-forming transformations. Trivalent phosphorus compounds called phosphines have a tetrahedral electron-group geometry which makes them structurally analogous to amines.Product Details of 1595319-95-1

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Baratta, Walter et al. published their research in Organometallics in 2005 | CAS: 77876-39-2

(2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) (cas: 77876-39-2) belongs to chiral phosphine ligands. Many phosphine-catalyzed reactions have been developed for the syntheses of various biologically important acyclic and cyclic molecules. Asymmetric variants of these reactions have evolved relatively slowly. Most of these phosphines are acyclic, usually possess low nucleophilic activity, and generally display poor enantioselectivities for phosphine organocatalysis. Formula: C29H30P2

2-(Aminomethyl)pyridine-Phosphine Ruthenium(II) Complexes: Novel Highly Active Transfer Hydrogenation Catalysts was written by Baratta, Walter;Herdtweck, Eberhardt;Siega, Katia;Toniutti, Micaela;Rigo, Pierluigi. And the article was included in Organometallics in 2005.Formula: C29H30P2 This article mentions the following:

Trans,cis-RuCl2(PPh3)2(ampy) (1) and trans-RuCl2[Ph2P(CH2)4PPh2](ampy) (2) were prepared in high yield by reaction of RuCl2(PPh3)3 and RuCl2(PPh3)[Ph2P(CH2)4PPh2] with 2-(aminomethyl)pyridine (ampy) at room temperature by PPh3 displacement. Heating compound 1 in refluxing toluene leads to the isomer cis,cis-RuCl2(PPh3)2(ampy) (3), which was proven to be a good precursor for the preparation of cis-RuCl2(PP)(ampy) [PP = (S,S)-Chiraphos, 4; Ph2P(CH2)3PPh2, 5; (S,S)-Skewphos, 6; Ph2P(CH2)4PPh2, 7; (R,R)-Diop, 8] by displacement of two PPh3 with the appropriate diphosphine. Cis-RuCl2(PP)(ampy) [PP = (R,S)-Josiphos, 9; (R,S)-tBu-Josiphos, 10] were synthesized from RuCl2(PPh3)3 and PP followed by addition of ampy. The chiral complexes 4, 6, 8, 9, and 10 are formed stereoselectively, as inferred by NMR data in solution For the derivatives 7 and 9 the mol. structures were determined by x-ray measurements. The monohydride complex trans,cis-RuHCl(PPh3)2(ampy) (11) was prepared from RuHCl(PPh3)3 and ampy in heptane by PPh3 substitution. Compound 11 reacts with Na isopropoxide in toluene, affording the dihydride derivative cis,trans-Ru(H)2(PPh3)2(ampy) (12) via the alkoxide route. The intermediate species cis,cis-Ru(H)2(PPh3)2(ampy) (A) was also characterized by NMR in solution All these complexes are highly efficient transfer hydrogenation catalysts. With cis-RuCl2(PP)(ampy) a large number of ketones (dialkyl, diaryl, and alkyl-aryl) can be quant. reduced to alcs. in iso-PrOH and in the presence of NaOH (ketone/Ru/NaOH = 2000/1/40) with remarkably high TOF values (up to 400,000 h-1 at 50% conversion). The derivatives containing chiral diphosphines afforded rapid (TOF > 105 h-1) and enantioselective (ee up to 94%) reduction of Me-aryl ketones using low loading of catalysts (0.05-0.01 mol %). In the absence of base the dihydride compound 12 catalyzes the transfer hydrogenation of acetophenone. In the experiment, the researchers used many compounds, for example, (2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) (cas: 77876-39-2Formula: C29H30P2).

(2S,4S)-Pentane-2,4-diylbis(diphenylphosphine) (cas: 77876-39-2) belongs to chiral phosphine ligands. Many phosphine-catalyzed reactions have been developed for the syntheses of various biologically important acyclic and cyclic molecules. Asymmetric variants of these reactions have evolved relatively slowly. Most of these phosphines are acyclic, usually possess low nucleophilic activity, and generally display poor enantioselectivities for phosphine organocatalysis. Formula: C29H30P2

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Bantreil, Xavier et al. published their research in Synlett in 2009 | CAS: 133545-16-1

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Over the last decade, however, and especially since 2005, considerable progress has been made in asymmetric phosphine catalysis.Recommanded Product: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)

Enantioselective γ-lactam synthesis via palladium-catalyzed intramolecular asymmetric allylic alkylation was written by Bantreil, Xavier;Prestat, Guillaume;Madec, David;Fristrup, Peter;Poli, Giovanni. And the article was included in Synlett in 2009.Recommanded Product: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) This article mentions the following:

A Pd(0)-catalyzed intramol. allylic alkylation in the presence of chiral atropisomeric bidentate ligands, e.g., (R)-3,5-t-Bu-MeOBIPHEP, takes place in up to 92:8 er in agreement with DFT calculations and provides easy access to enantioenriched disubstituted γ-lactams. E.g., 2.5 mol% [Pd(η3-C3H5)Cl]2 in CH2Cl2 was added to 7.5 mol% (R)-BINAP at room temperature to which 1 equivalent of MeO2CCH2C(O)B(Bn)CH2CH:CHCH2OAc in CH2Cl2, BSA and KOAc were successively added to give N-benzyl-3-carbomethoxy-4-vinyl-γ-lactam in 88% yield. In the experiment, the researchers used many compounds, for example, (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1Recommanded Product: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)).

(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Over the last decade, however, and especially since 2005, considerable progress has been made in asymmetric phosphine catalysis.Recommanded Product: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis

Praz, Jezabel et al. published their research in Advanced Synthesis & Catalysis in 2012 | CAS: 134484-36-9

(S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Electric Literature of C33H25OP

Evaluation of the Chiral DIANANE Backbone as Ligand for Organolithium Reagents was written by Praz, Jezabel;Guenee, Laure;Aziz, Sarwar;Berkessel, Albrecht;Alexakis, Alexandre. And the article was included in Advanced Synthesis & Catalysis in 2012.Electric Literature of C33H25OP This article mentions the following:

Novel endo,endo-2,5-diaminonorbonane-derived tertiary C2-sym. diamines were synthesized via the one-pot reductive amination of enantiomerically pure norbornane-2,5-dione. These ligands were applied to various catalytic reactions such as asym. deprotonation, asym. bromine-lithium exchange, and enantioselective addition of aryl- and alkylithium reagents to aromatic aldimines. In the experiment, the researchers used many compounds, for example, (S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9Electric Literature of C33H25OP).

(S)-(2′-Methoxy-[1,1′-binaphthalen]-2-yl)diphenylphosphine (cas: 134484-36-9) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.Electric Literature of C33H25OP

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis