Palladium-catalyzed DYKAT of butadiene mono-epoxide: enantioselective total synthesis of (+)-DMDP, (-)-bulgecinine, and (+)-broussonetine G was written by Trost, Barry M.;Horne, Daniel B.;Woltering, Michael J.. And the article was included in Chemistry – A European Journal in 2006.SDS of cas: 174810-09-4 This article mentions the following:
Palladium catalyzed DYKAT (dynamic kinetic asym. transformation) allylic alkylation reaction of an amine with two equivalent of butadiene monoxide allows for the expedient synthesis of trans- and cis-2,5-dihydropyrroles. The versatility of these chiral synthons towards the synthesis of a wide variety of imino-sugar natural products was demonstrated with the short and high yielding asym. syntheses of (+)-DMDP, and (-)-bulgecinine. In addition, the first total synthesis of (+)-broussonetine G, a potent glycosidase inhibitor, is described along with the assignment of its relative and absolute stereochem. configuration. In the experiment, the researchers used many compounds, for example, N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide) (cas: 174810-09-4SDS of cas: 174810-09-4).
N,N’-((1R,2R)-Cyclohexane-1,2-diyl)bis(2-(diphenylphosphino)-1-naphthamide) (cas: 174810-09-4) belongs to chiral phosphine ligands. Phosphine-catalyzed asymmetric reactions are now powerful and versatile tools for the construction of C–C, C–N, C–O, and C–S bonds and for the syntheses of functionalized carbocycles and heterocycles. Over the last decade, however, and especially since 2005, considerable progress has been made in asymmetric phosphine catalysis.SDS of cas: 174810-09-4
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis