Synthesis of novel chiral phosphine-olefin complexes and their evaluation as ligands in the rhodium-catalyzed asymmetric 1,4-addition was written by Stemmler, Rene T.;Bolm, Carsten. And the article was included in Synlett in 2007.COA of Formula: C26H28FeNP This article mentions the following:
Novel chiral phosphine-olefin complexes containing ferrocene and cyrhetrene backbones were synthesized and evaluated as ligands in the Rh-catalyzed 1,4-addition of phenylboronic acid to cyclohexenone. The highest efficiency in this series was observed with planar-chiral ligands (Sp)-1-(diphenylphosphino)-2-vinylferrocene and (Sp)-tricarbonyl[η5-1-(diphenylphosphino)-2-ethenylcyclopentadienyl]rhenium, which furnished the corresponding product with up to 71% ee. In the experiment, the researchers used many compounds, for example, (R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (cas: 55700-44-2COA of Formula: C26H28FeNP).
(R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (cas: 55700-44-2) belongs to chiral phosphine ligands. Phosphine-catalyzed asymmetric reactions are now powerful and versatile tools for the construction of C–C, C–N, C–O, and C–S bonds and for the syntheses of functionalized carbocycles and heterocycles. Chiral ligands coordinate to metal centers to create an asymmetric environment around the reaction centers, which eventually affects enantioselectivity and reaction rate.COA of Formula: C26H28FeNP
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis