Efficient P,N,N-type ligands for Ru(II)-catalyzed asymmetric cyclopropanations was written by Dai, Huicong;Hu, Xiangping;Chen, Huilin;Bai, Changmin;Zheng, Zhuo. And the article was included in Journal of Molecular Catalysis A: Chemical in 2004.Formula: C26H28FeNP This article mentions the following:
Novel chiral P,N,N-type ligands I (R = Me, R1 = H, Me; R = Et, Ph, R1 = H) derived from (R)-(S)-PPFNH2-R and 2-pyridinecarboxaldehydes were employed in Ru(II)-catalyzed asym. cyclopropanation of styrene with Et diazoacetate. Up to 99% yield with 95% e.e. for cis-isomer and 90% e.e. for trans-isomer was obtained on Ru(II)/I (R = Me, R1 = H). In the experiment, the researchers used many compounds, for example, (R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (cas: 55700-44-2Formula: C26H28FeNP).
(R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (cas: 55700-44-2) belongs to chiral phosphine ligands. Although many reactions require more nucleophilic trialkylphosphines as catalysts, only a few chiral trialkylphosphines are available. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Formula: C26H28FeNP
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis