Enantioselective C-C Bond Cleavage Creating Chiral Quaternary Carbon Centers was written by Matsuda, Takanori;Shigeno, Masanori;Makino, Masaomi;Murakami, Masahiro. And the article was included in Organic Letters in 2006.Name: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) This article mentions the following:
A chiral all-carbon benzylic quaternary carbon center was created by the asym. intramol. addition/ring-opening reaction of a boryl-substituted cyclobutanone, which involved enantioselective β-carbon elimination from a sym. rhodium cyclobutanolate. The asym. reaction was successfully applied to a synthesis of sesquiterpene, (-)-α-herbertenol (I). In the experiment, the researchers used many compounds, for example, (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1Name: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)).
(R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine) (cas: 133545-16-1) belongs to chiral phosphine ligands. The synthesis of novel trialkylphosphines can be quite difficult, thereby limiting the scope of their chiral variants. Most of these phosphines are acyclic, usually possess low nucleophilic activity, and generally display poor enantioselectivities for phosphine organocatalysis. Name: (R)-(6,6′-Dimethoxy-[1,1′-biphenyl]-2,2′-diyl)bis(diphenylphosphine)
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis