Enantioselective vinylation of aldehydes with chiral β-silylphosphorus ylides was written by Iio, Hideo;Fujii, Akio;Ishii, Masahiro;Tokoroyama, Takashi. And the article was included in Journal of the Chemical Society, Chemical Communications in 1991.Name: (R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine This article mentions the following:
Both enantiomers of diastereoisomeric [1-(dimethylaminoethyl)ferrocenyl]diphenyl(2-diphenylmethylsilylethylidene)phosphorane are prepared; their reaction with benzaldehyde and aliphatic aldehydes is found to give vinylation products with variable enantiomeric excess (up to 92%). In the experiment, the researchers used many compounds, for example, (R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (cas: 55700-44-2Name: (R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine).
(R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (cas: 55700-44-2) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Effective chiral catalysts for nucleophilic phosphine catalysis are scarce, seriously limiting the development of asymmetric variants. Name: (R)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis