Platinum(II) Catalyzed Enantioselective Cycloisomerizations of 3-Hydroxylated 1,5-Enynes was written by Zhang, Yang;Jullien, Helene;Brissy, Delphine;Retailleau, Pascal;Voituriez, Arnaud;Marinetti, Angela. And the article was included in ChemCatChem in 2013.Computed Properties of C24H22NO2P This article mentions the following:
The enantioselective cycloisomerization of 3-hydroxylated 1,5-enynes into bicyclo[3.1.0]hexanones was investigated by using cyclometalated NHC-platinum phosphoramidite complexes as precatalysts. Several new complexes were prepared They generate cationic, electrophilic PtII species that efficiently promote the cycloisomerization process. Enantiomeric excesses up to 81% were obtained in the reactions of enynes with aryl-substituted alkyne functions (8 examples, 70-81% ee). In the experiment, the researchers used many compounds, for example, (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3Computed Properties of C24H22NO2P).
(11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3) belongs to chiral phosphine ligands. Although many reactions require more nucleophilic trialkylphosphines as catalysts, only a few chiral trialkylphosphines are available. Indeed, very little research on chiral tertiary phosphine-catalyzed asymmetric reactions occurred prior to the year 2000.Computed Properties of C24H22NO2P
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis