Asymmetric 1,4-addition of organoboron reagents to quinone monoketals catalyzed by a chiral diene/rhodium complex: a new synthetic route to enantioenriched 2-aryltetralones was written by Tokunaga, Norihito;Hayashi, Tamio. And the article was included in Advanced Synthesis & Catalysis in 2007.Application In Synthesis of (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine This article mentions the following:
A novel synthetic approach to 2-aryltetralones with high ee has been developed through asym. 1,4-addition of arylboronic acids to naphthoquinone monoketals catalyzed by a rhodium complex with the (R,R)-Ph-bod* ligand. The asym. addition proceeded in high yields with excellent enantioselectivity. In the experiment, the researchers used many compounds, for example, (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3Application In Synthesis of (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine).
(11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Asymmetric catalytic performance is determined not only by the metal center but also by the chiral ligand selected.Application In Synthesis of (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis