Li, Kangying et al. published their research in Heteroatom Chemistry in 2003 | CAS: 252288-04-3

(11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Safety of (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine

Synthesis of chiral phosphorus reagents and their catalytic activity in asymmetric borane reduction of N-phenylimine of acetophenone was written by Li, Kangying;Zhou, Zhenghong;Zhao, Guofeng;Tang, Chuchi. And the article was included in Heteroatom Chemistry in 2003.Safety of (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine This article mentions the following:

Eleven chiral trivalent or quadrivalent phosphorus reagents were synthesized starting from L-proline, D-camphor, (+)- or (-)-1,1′-binaphthalene-2,2′-diol, (-)-α-phenylethylamine, etc. and their application as catalysts in asym. borane reduction of PhMeC:NPh was investigated. PhMeCHNHPh was obtained in good yield with low to moderate enantioselectivity. In the experiment, the researchers used many compounds, for example, (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3Safety of (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine).

(11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine (cas: 252288-04-3) belongs to chiral phosphine ligands. Thousands of arylphosphines have been used as chiral ligands for metal-catalyzed asymmetric reactions. Chiral phosphine catalysts: Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates.Safety of (11bS)-N,N-Diethyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine

Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis