Convergent Asymmetric Disproportionation Reactions: Metal/Bronsted Acid Relay Catalysis for Enantioselective Reduction of Quinoxalines was written by Chen, Qing-An;Wang, Duo-Sheng;Zhou, Yong-Gui;Duan, Ying;Fan, Hong-Jun;Yang, Yan;Zhang, Zhang. And the article was included in Journal of the American Chemical Society in 2011.Recommanded Product: 1043567-32-3 This article mentions the following:
A convergent asym. disproportionation of dihydroquinoxalines for the synthesis of chiral tetrahydroquinoxalines using a metal/Bronsted acid relay catalysis system has been developed. The use of hydrogen gas as the reductant makes the convergent disproportionation an ideal atom-economical process. A dramatic reversal of enantioselectivity was observed in the reduction of quinoxalines because of the different steric demands in the 1,2- and 1,4-hydride transfer pathways. In the experiment, the researchers used many compounds, for example, (11bS)-4-Hydroxy-2,6-di(phenanthren-9-yl)dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine 4-oxide (cas: 1043567-32-3Recommanded Product: 1043567-32-3).
(11bS)-4-Hydroxy-2,6-di(phenanthren-9-yl)dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine 4-oxide (cas: 1043567-32-3) belongs to chiral phosphine ligands. Although many reactions require more nucleophilic trialkylphosphines as catalysts, only a few chiral trialkylphosphines are available. Over the last decade, however, and especially since 2005, considerable progress has been made in asymmetric phosphine catalysis.Recommanded Product: 1043567-32-3
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis