Sun, Meng published the artcileCatalytic Asymmetric (4+3) Cyclizations of In Situ Generated ortho-Quinone Methides with 2-Indolylmethanols, Formula: C50H65O4P, the publication is Angewandte Chemie, International Edition (2019), 58(26), 8703-8708, database is CAplus and MEDLINE.
The first catalytic asym. (4+3) cyclization of in situ generated ortho-quinone methides with 2-indolylmethanols has been established, which constructed seven-membered heterocycles in high yields (up to 95 %) and excellent enantioselectivity (up to 98 %). This approach not only represents the first catalytic asym. (4+3) cyclization of o-hydroxybenzyl alcs., but also enabled an unprecedented catalytic asym. (4+3) cyclization of 2-indolylmethanols. In addition, a scarcely reported catalytic asym. (4+3) cyclization of para-quinone methide derivatives was accomplished.
Angewandte Chemie, International Edition published new progress about 929294-27-9. 929294-27-9 belongs to chiral-phosphine-ligands, auxiliary class Chiral Phosphoric Acids, name is R-3,3′-Bis(2,4,6-triisopropylphenyl)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate, and the molecular formula is C11H17BO3S, Formula: C50H65O4P.
Referemce:
https://en.wikipedia.org/wiki/Phosphine_ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate