In 2022,Yang, Ninglei; Dong, Ming; Tong, Xiaofeng published an article in Organic Letters. The title of the article was 《Pd(0)-Catalyzed Intramolecular Reductive Heck Reaction of Vinyl Iodide and Oxime Ether: Enantioselective Synthesis of Cyclic Allylic N-Alkoxy Amine》.Product Details of 210169-54-3 The author mentioned the following in the article:
Reported the Pd(0)-catalyzed intramol. reductive Heck reaction of vinyl iodide and oxime ether with the use of formic acid as the reductant. It was found that the TsOH additive plays a crucial role in the reaction efficiency and the (S)-SEGPhos ligand enables cyclic allylic N-alkoxy amine products with high enantioselectivity. After reading the article, we found that the author used (S)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole(cas: 210169-54-3Product Details of 210169-54-3)
(S)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole(cas: 210169-54-3) is a chelating ligand used to prepare coordination complex catalysts, such as its use in Pd catalysts for the enantioselective synthesis of spiro- or benzofused hetereocycles with exocyclic olefins via enantioselective intramolecular dearomative Heck reaction of indoles, benzofurans, pyrroles and furans.Product Details of 210169-54-3
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis