Tanaka, Ken; Otake, Yousuke; Sagac, Hiromi; Noguchi, Keiichi; Hirano, Masao published the artcile< Highly regio-, diastereo-, and enantioselective [2 + 2 + 2] cycloaddition of 1,6-enynes with electron-deficient ketones catalyzed by a cationic RhI/H8-binap complex>, Computed Properties of 139139-86-9, the main research area is enyne stereoselective cyclocondensation keto ester amide diketone; rhodium BINAP regioselective diastereoselective enantioselective cycloaddition ortho functionalization; pyran dihydro heterocycle fused regioselective stereoselective preparation; ketone aryl ortho functionalization enyne rhodium catalyst.
A cationic RhI/H8-binap complex catalyzed regio-, diastereo-, and enantioselective [2 + 2 + 2] cycloaddition of 1,6-enynes with electron-deficient ketones to form fused dihydropyrans containing two quaternary carbon centers, e.g., I, is reported. Electron-rich aryl ketones react with 1,6-enynes in the presence of the same catalyst to give ortho-functionalized aryl ketones with excellent regio- and enantioselectivity.
Angewandte Chemie, International Edition published new progress about Alkenynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (1,6-). 139139-86-9 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Computed Properties of 139139-86-9.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate