Yoshizaki, Soichi’s team published research in Organic Letters in 2016-02-05 | 139139-93-8

Organic Letters published new progress about [2+2+2] Cycloaddition reaction. 139139-93-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Reference of 139139-93-8.

Yoshizaki, Soichi; Nakamura, Yu; Masutomi, Koji; Yoshida, Tomoka; Noguchi, Keiichi; Shibata, Yu; Tanaka, Ken published the artcile< Rhodium-Catalyzed Asymmetric [2 + 2 + 2] Cycloaddition of 1,6-Enynes with Cyclopropylideneacetamides>, Reference of 139139-93-8, the main research area is asym cycloaddition enyne cyclopropylideneacetamide rhodium catalyst.

It has been established that a cationic rhodium(I)/(S)-H8-BINAP complex catalyzes the asym. [2+2+2] cycloaddition of 1,6-enynes with cyclopropylideneacetamides to produce spirocyclohexenes in excellent enantioselectivity with retaining cyclopropane rings. E.g., in presence of [Rh(cod)2]BF4 and (S)-H8-BINAP, [2+2+2] cycloaddition of MeCCCH2NTsCH2CMe:CH2 and N-methyl-N-phenylcyclopropylideneacetamide gave 69% I (>99%ee).

Organic Letters published new progress about [2+2+2] Cycloaddition reaction. 139139-93-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Reference of 139139-93-8.

Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate