Hayashi, Tamio; Kawai, Masahiro; Tokunaga, Norihito published the artcile< Asymmetric synthesis of diarylmethyl amines by rhodium-catalyzed asymmetric addition of aryl titanium reagents to imines>, Name: (S)-(-)-2,2′-Bis(diphenylphosphino)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl, the main research area is arylsulfonyl arylimine aryltitanium asym addition rhodium; arylamine arylsulfonyl stereoselective preparation desulfonylation; amine diarylmethyl stereoselective preparation.
Rhodium/chiral phosphine-catalyzed asym. addition of aryltitanium triisopropoxides to N-arylidene sulfonamides (Ar1CH=NSO2Ar2) yielded diarylmethyl arylsulfonamides, e.g., I, enantioselectively. A rational tuning of the arene sulfonamide moiety (by introducing iso-Pr groups onto the Ph ring) brought about high enantioselectivity in the reaction. Desulfonylation of the diarylmethyl arylsulfonamides yielded chiral diarylmethyl amines, e.g., II.
Angewandte Chemie, International Edition published new progress about Addition reaction catalysts, stereoselective. 139139-93-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Name: (S)-(-)-2,2′-Bis(diphenylphosphino)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate